Skip to main content
Log in

Sequence and phylogenetic analysis of H7N3 avian influenza viruses isolated from poultry in China in 2011

  • Annotated Sequence Record
  • Published:
Archives of Virology Aims and scope Submit manuscript

Abstract

Four H7N3 avian influenza viruses (AIVs) were isolated from domestic ducks in live-poultry markets in Zhejiang Province, Eastern China, in 2011. All viruses were characterized by whole-genome sequencing with subsequent phylogenetic analysis and genetic comparison. Phylogenetic analysis of all eight viral genes showed that the viruses clustered in the Eurasian lineage of influenza viruses. The hemagglutinin cleavage site of all viruses indicated that the four strains were low-pathogenic avian influenza viruses.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Webster RG, Bean WJ, Gorman OT, Chambers TM, Kawaoka Y (1992) Evolution and ecology of influenza A viruses. Microbiol Rev 56:152–179

    PubMed  CAS  Google Scholar 

  2. Alexander DJ (2000) A review of avian influenza in different bird species. Vet Microbiol 74(1–2):3–13

    Article  PubMed  CAS  Google Scholar 

  3. Mannelli A, Busani L, Toson M, Bertolini S, Marangon S (2007) Transmission parameters of highly pathogenic avian influenza (H7N1) among industrial poultry farms in northern Italy in 1999–2000. Prev Vet Med 81(4):318–322

    Article  PubMed  CAS  Google Scholar 

  4. Di Trani L, Bedini B, Cordioli P, Muscillo M, Vignolo E, Moreno A, Tollis M (2004) Molecular characterization of low pathogenicity H7N3 avian influenza viruses isolated in Italy. Avian Dis 48(2):376–383

    Article  PubMed  Google Scholar 

  5. Spackman E, Senne DA, Davison S, Suarez DL (2003) Sequence analysis of recent H7 avian influenza viruses associated with three different outbreaks in commercial poultry in the United States. J Virol 77(24):13399–13402

    Article  PubMed  CAS  Google Scholar 

  6. van Kolfschooten F (2003) Dutch veterinarian becomes first victim of avian influenza. Lancet 361(9367):1444

    Article  PubMed  Google Scholar 

  7. Koopmans M, Wilbrink B, Conyn M, Natrop G, van der Nat H, Vennema H, Meijer A, van Steenbergen J, Fouchier R, Osterhaus A, Bosman A (2004) Transmission of H7N7 avian influenza A virus to human beings during a large outbreak in commercial poultry farms in the Netherlands. Lancet 363(9409):587–593

    Article  PubMed  Google Scholar 

  8. Skowronski DM, Tweed SA, Petric M, Booth T, Li Y, Tam T (2006) Human illness and isolation of low-pathogenicity avian influenza virus of the H7N3 subtype in British Columbia. Canada. J Infect Dis 193(6):899–900

    Article  Google Scholar 

  9. Li Y, Li C, Liu L, Wang H, Wang C, Tian G, Webster RG, Yu K, Chen H (2006) Characterization of an avian influenza virus of subtype H7N2 isolated from chickens in northern China. Virus Genes 33(1):117–122

    Article  PubMed  CAS  Google Scholar 

  10. Wu HB, Guo CT, Lu RF, Xu LH, Wo EK, You JB, Wang YT, Wang QG, Wu NP (2012) Genetic characterization of subtype H1 avian influenza viruses isolated from live poultry markets in Zhejiang Province, China, in 2011. Virus Genes 44(3):441–449

    Article  PubMed  CAS  Google Scholar 

  11. Horimoto T, Ito T, Alexander DJ, Kawaoka Y (1995) Cleavability of hemagglutinin from an extremely virulent strain of avian influenza virus containing a unique cleavage site sequence. J Vet Med Sci 57(5):927–930

    Article  PubMed  CAS  Google Scholar 

  12. Lee CW, Lee YJ, Senne DA, Suarez DL (2006) Pathogenic potential of North American H7N2 avian influenza virus: a mutagenesis study using reverse genetics. Virology 353(2):388–395

    Article  PubMed  CAS  Google Scholar 

  13. Yang H, Chen LM, Carney PJ, Donis RO, Stevens J (2010) Structures of receptor complexes of a North American H7N2 influenza hemagglutinin with a loop deletion in the receptor binding site. PLoS Pathog 6(9):e1001081

    Article  PubMed  Google Scholar 

  14. Gambaryan AS, Matrosovich TY, Philipp J, Munster VJ, Fouchier RA, Cattoli G, Capua I, Krauss SL, Webster RG, Banks J, Bovin NV, Klenk HD, Matrosovich MN (2012) Receptor-binding profiles of h7 subtype influenza viruses in different host species. J Virol 86(8):4370–4379

    Article  PubMed  CAS  Google Scholar 

  15. Liu J, Stevens DJ, Haire LF, Walker PA, Coombs PJ, Russell RJ, Gamblin SJ (1957) Skehel JJ (2009) Structures of receptor complexes formed by hemagglutinins from the Asian Influenza pandemic of. Proc Natl Acad Sci USA 106(40):17175–17180

    Article  Google Scholar 

  16. Helenius A, Aebi M (2004) Roles of N-linked glycans in the endoplasmic reticulum. Annu Rev Biochem 73:1019–1049

    Article  PubMed  CAS  Google Scholar 

  17. Aoki FY, Boivin G, Roberts N (2007) Influenza virus susceptibility and resistance to oseltamivir. Antivir Ther 12:603–616

    PubMed  CAS  Google Scholar 

  18. Deyde VM, Xu X, Bright RA, Shaw M, Smith CB, Zhang Y, Shu Y, Gubareva LV, Cox NJ, Klimov AI (2007) Surveillance of resistance to adamantanes among influenza A (H3N2) and A (H1N1) viruses isolated worldwide. J Infect Dis 196(2):249–257

    Article  PubMed  CAS  Google Scholar 

  19. Hirst M, Astell CR, Griffith M, Coughlin SM, Moksa M, Zeng T, Smailus DE, Holt RA, Jones S, Marra MA, Petric M, Krajden M, Lawrence D, Mak A, Chow R, Skowronski DM, Tweed SA, Goh S, Brunham RC, Robinson J, Bowes V, Sojonky K, Byrne SK, Li Y, Kobasa D, Booth T, Paetzel M (2004) Novel avian influenza H7N3 strain outbreak, British Columbia. Emerg Infect Dis 10(12):2192–2195

    Article  PubMed  CAS  Google Scholar 

  20. Pasick J, Handel K, Robinson J, Copps J, Ridd D, Hills K, Kehler H, Cottam-Birt C, Neufeld J, Berhane Y, Czub S (2005) Intersegmental recombination between the haemagglutinin and matrix genes was responsible for the emergence of a highly pathogenic H7N3 avian influenza virus in British Columbia. J Gen Virol 86(Pt 3):727–731

    Article  PubMed  CAS  Google Scholar 

Download references

Acknowledgments

This study was supported by grants from the National Science Foundation of the People’s Republic of China (30872163), National Key Technologies R&D Programme for the 12th Five-Year Plan of China (2012ZX1000-004-005) and the State Key Laboratory of Independent Task. This study was sponsored by Zhejiang Provincial Program for the Cultivation of High-Level Innovative Health Talents.

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Wu Nan-ping or Guo Chao-tan.

Additional information

Wu Hai-bo and Lu Ru-feng contributed equally to the work.

Electronic supplementary material

Below is the link to the electronic supplementary material.

Supplementary material 1 (RAR 322 kb)

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hai-bo, W., Ru-feng, L., En-kang, W. et al. Sequence and phylogenetic analysis of H7N3 avian influenza viruses isolated from poultry in China in 2011. Arch Virol 157, 2017–2021 (2012). https://doi.org/10.1007/s00705-012-1370-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00705-012-1370-3

Keywords

Navigation