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Stereotactic radiosurgery as a primary treatment for metastatic skull base alveolar soft part sarcoma: a case report

  • Case Report - Brain Tumors
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Abstract

Alveolar soft part sarcoma (ASPS) is a rare malignancy that typically arises in the trunk or extremities and preferentially metastasises to the brain. Radical resection is generally recommended for cranial metastatic ASPS, but stereotactic radiosurgery (SRS) is a recognised alternative for tumours in surgically challenging locations. Here, we present the case of a 22-year-old female, who underwent SRS and systemic therapy with pazopanib for a metastatic ASPS in the left temporal bone. The tumour was successfully controlled without further intervention over 23 months following SRS, which should be considered for metastatic ASPS when surgical resection is not appropriate.

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Abbreviations

ASPS:

Alveolar soft part sarcoma

SRS:

Stereotactic radiosurgery

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Authors and Affiliations

  1. Department of Neurosurgery, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan

    Yuki Shinya, Hirotaka Hasegawa, Mariko Kawashima, Masahiro Shin & Nobuhito Saito

  2. Department of Neurologic Surgery, Mayo Clinic, Rochester, MN, USA

    Hirotaka Hasegawa

  3. Department of Radiology, The University of Tokyo Hospital, Tokyo, Japan

    Wataru Takahashi

  4. Department of Orthopedic Surgery, The University of Tokyo Hospital, Tokyo, Japan

    Hiroshi Kobayashi

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  1. Yuki Shinya
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  2. Hirotaka Hasegawa
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  3. Mariko Kawashima
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  4. Masahiro Shin
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  5. Wataru Takahashi
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Correspondence to Yuki Shinya.

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Shinya, Y., Hasegawa, H., Kawashima, M. et al. Stereotactic radiosurgery as a primary treatment for metastatic skull base alveolar soft part sarcoma: a case report. Acta Neurochir 163, 351–355 (2021). https://doi.org/10.1007/s00701-020-04496-2

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  • DOI: https://doi.org/10.1007/s00701-020-04496-2

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