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Photoelectrochemical aptasensing of oxytetracycline based on a BiVO4-carboxylated graphene-WO3 Z-scheme heterojunction

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Abstract

A new BiVO4-carboxylated graphene (cG)-WO3 Z-scheme heterojunction was constructed on a fluorine-doped tin oxide (FTO) substrate electrode by ultrasonic mixing and cast-coating for determination of oxytetracycline (OTC). Since cG can absorb visible light and well match with the energy levels of WO3 and BiVO4 to promote the charge separation and transfer, the photocurrent on the BiVO4-cG-WO3/FTO photoelectrode is 4.4 times that on the control BiVO4-WO3/FTO photoelectrode. An amino-functionalized OTC aptamer was fixed on the BiVO4-cG-WO3/FTO photoelectrode by the 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide/N-hydroxysuccinimide mediated amide reaction, and then hexaammonium ruthenium(III) (Ru(NH3)63+) was attached to the OTC aptamer to increase the photocurrent response to the OTC binding. Under the optimized conditions, the photocurrent on the BiVO4-cG-WO3/FTO photoelectrode at 0 V vs SCE was linear with the common logarithm of OTC concentration from 0.01 nM to 500 nM, with a limit of detection of 3.1 pM (S/N = 3). Satisfactory recovery results were obtained in the analysis of real water samples.

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Acknowledgements

This work was supported by the National Natural Science Foundation of China (22074039, 21675050).

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Authors and Affiliations

  1. Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research (Ministry of Education of China), College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha, 410081, China

    Yuru Shen, Chenglong Sun, Mingjian Chen, Yun Du, Jun Cheng, Yunlong Li & Qingji Xie

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Contributions

Yuru Shen: Conceptualization, Writing-original draft. Chenglong Sun: Investigation. Mingjian Chen: Investigation. Yun Du: Investigation. Jun Cheng: Investigation. Yunlong Li: Investigation, Funding acquisition, Writing—review & editing, Qingji Xie: Conceptualization, Funding acquisition, Writing—review & editing.

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Correspondence to Yunlong Li or Qingji Xie.

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Shen, Y., Sun, C., Chen, M. et al. Photoelectrochemical aptasensing of oxytetracycline based on a BiVO4-carboxylated graphene-WO3 Z-scheme heterojunction. Microchim Acta 190, 193 (2023). https://doi.org/10.1007/s00604-023-05742-x

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