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A mesoporous silver-doped TiO2-SnO2 nanocomposite on g-C3N4 nanosheets and decorated with a hierarchical core−shell metal-organic framework for simultaneous voltammetric determination of ascorbic acid, dopamine and uric acid

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Abstract

An electrochemical sensor is described for the simultaneous voltammetric determination of ascorbic acid (AA), dopamine (DA), and uric acid (UA). An indium-tin oxide (ITO) electrode was modified with a hierarchical core−shell metal-organic framework and Ag-doped mesoporous metal-oxide based hybrid nanocomposites on g-C3N4 nanosheets. The morphology, structural and chemical composition of the hybrid nanocomposite was characterized using different analytical methods. The modified ITO showed superior electrocatalytic performance towards the oxidation of AA, DA and UA due to the enhanced surface area, synergistic effects and well-organized porous assembly. Figures of merit, include (a) linear responses from 0.1 to 200 μM, 2.5 to 100 μM and 2.5 to 625 μM; (b) detection limits (at S/N = 3) of 0.02, 0.01 and 0.06 μM, and (c) well separated oxidation peaks near −50, 186 and 390 mV (vs. Ag/AgCl) for simultaneous sensing AA, DA and UA, respectively. The sensor was evaluated by analysing spiked serum samples and gave data with precision, with recoveries of >98%.

Schematic Representation of a Mesoporous Silver-doped TiO2-SnO2 Nanocomposite (h-ATS) on g-C3N4 Nanosheets and Decorated with a Hierarchical Core−Shell Metal-Organic Framework (NC@GC) Based Electrochemical Sensor for Simultaneous Voltammetric Detection of Ascorbic acid, Dopamine and Uric acid

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Acknowledgements

The authors gratefully appreciate the support from the National Natural Science Foundation of China (21950410531), and Science & Technology Research Project of Henan province (182102410090). Also, we express thanks to Dr. Daibing Luo from the Analytical & Testing Center of Sichuan University for the valuable discussion and characterisation.

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Authors and Affiliations

  1. Henan Key Laboratory of Polyoxometalate Chemistry, Henan Joint International Research Laboratory of environmental pollution control materials, College of Chemistry and Chemical Engineering, Henan University, Kaifeng, 47504, People’s Republic of China

    Srinivasan Krishnan, Liangyu Tong, Shanhu Liu & Ruimin Xing

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  1. Srinivasan Krishnan
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  2. Liangyu Tong
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  3. Shanhu Liu
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Correspondence to Shanhu Liu.

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Krishnan, S., Tong, L., Liu, S. et al. A mesoporous silver-doped TiO2-SnO2 nanocomposite on g-C3N4 nanosheets and decorated with a hierarchical core−shell metal-organic framework for simultaneous voltammetric determination of ascorbic acid, dopamine and uric acid. Microchim Acta 187, 82 (2020). https://doi.org/10.1007/s00604-019-4045-x

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