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Imprinted voltammetric streptomycin sensor based on a glassy carbon electrode modified with electropolymerized poly(pyrrole-3-carboxy acid) and electrochemically reduced graphene oxide

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Abstract

The authors describe a voltammetric sensor for trace analysis of streptomycin (STR). It is based on the use of a glassy carbon electrode that was modified with a film of STR-imprinted poly(pyrrole-3-carboxy acid) (PPy3C) on electrochemically reduced graphene oxide (ERGO). ERGO was first deposited on the surface of GCE by electro-reduction, this followed by deposition of a film of STR-imprinted PPy3C. The morphologies and properties of the sensor were characterized by scanning electron microscopy, cyclic voltammetry, and differential pulse voltammetry. Under optimized conditions, the sensor for STR displays two linear ranges that cover the 2 to 80, and the 80 to 1000 nM concentration range. Other features include a 0.5 nM limit of detection, good molecular recognition, and reliable practicability. Results indicate that the method provides a promising biomimetic platform for the determination of STR in food such as porcine kidney and honey.

A voltammetric sensor for trace analysis of streptomycin (STR) is described. It is based on the use of a glassy carbon electrode (GCE) that was modified with a film of STR-imprinted poly(pyrrole-3-carboxy acid) (PPy3C) on electrochemically reduced graphene oxide (ERGO).

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Acknowledgements

This work was supported by the National Science Foundation of China (51662014 and 31660492), Postdoctoral Science Foundation of China (2015 M571987), Jiangxi Provincial Department of Education (GJJ150428, GJJ13259). Special Funds for Jiangxi Province Postdoctoral Research Funds (2015KY44), the authors also gratefully acknowledge the financial support of this work by Scientific Research Foundation for Doctor.

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Authors and Affiliations

  1. Key Laboratory of Applied Chemistry, College of Science, Jiangxi Agricultural University, Nanchang, 330045, People’s Republic of China

    Yangping Wen, Xiaoning Liao, Changxi Deng, Guangbin Liu, Qianwen Yan, Linjian Li & Xiaoqiang Wang

  2. Key Laboratory of Crop Physiology, Ecology and Genetic Breeding, Ministry of Education, Jiangxi Agricultural University, Nanchang, 330045, China

    Yangping Wen & Xiaoqiang Wang

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  1. Yangping Wen
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  2. Xiaoning Liao
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  3. Changxi Deng
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  4. Guangbin Liu
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  5. Qianwen Yan
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Correspondence to Xiaoqiang Wang.

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Wen, Y., Liao, X., Deng, C. et al. Imprinted voltammetric streptomycin sensor based on a glassy carbon electrode modified with electropolymerized poly(pyrrole-3-carboxy acid) and electrochemically reduced graphene oxide. Microchim Acta 184, 935–941 (2017). https://doi.org/10.1007/s00604-017-2089-3

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  • DOI: https://doi.org/10.1007/s00604-017-2089-3

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