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Nonenzymatic amperometric glucose sensor based on a composite prepared from CuO, reduced graphene oxide, and carbon nanotube

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Abstract

The authors demonstrate a non-enzymatic sensor for glucose that is making used of an electrode prepared from an ink composed of CuO, reduced graphene oxide and carbon nanotube (CuO/rGO/CNT) on various substrates via dipping and drying. The morphology of the CuO/rGO/CNT composite was characterized via scanning electron microscopy and its composition was confirmed via X-ray diffraction measurements. The stacking of individual rGO sheets is prevented in the rGO and CNT hybrid, and this creates large surface areas and allows for fast electron and mass transport. The composite was deposited on nickel foam and the resulting electrode is shown to be a viable amperometric sensor for glucose, with a sensitivity of 9278 μA⋅mM−1⋅cm−2 over the 10 to 1000 μM glucose concentration range. The sensor was applied to the determination of glucose in spiked human serum samples.

A non-enzymatic sensor for glucose that is making used of an electrode prepared from an ink composed of CuO, reduced graphene oxide and carbon nanotube on various substrates via facile dipping and drying.

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Acknowledgments

This study was supported by the Energy Efficiency & Resources of the Korea Institute of Energy Technology Evaluation and Planning (KETEP) grant funded by the Korea government Ministry of Knowledge Economy (No. 20142010102690) and by Ministry of Science, ICT and Futrue Planning of Korea (Grant no. 2016–228389).

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    Authors and Affiliations

    1. School of Chemical Engineering, Sungkyunkwan University, Suwon, 440-746, Republic of Korea

      Changmi Lee, Sang Ha Lee, Misuk Cho & Youngkwan Lee

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    1. Changmi Lee
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    2. Sang Ha Lee
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    3. Misuk Cho
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    4. Youngkwan Lee
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    Correspondence to Misuk Cho or Youngkwan Lee.

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    Misuk Cho and Youngkwan Lee contributed equally to this work.

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    Lee, C., Lee, S.H., Cho, M. et al. Nonenzymatic amperometric glucose sensor based on a composite prepared from CuO, reduced graphene oxide, and carbon nanotube. Microchim Acta 183, 3285–3292 (2016). https://doi.org/10.1007/s00604-016-1984-3

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