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Infected False Aneurysms of the Limbs Secondary to Chronic Intravenous Drug Abuse: Analysis of Perioperative Considerations and Operative Outcomes

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Abstract

Purpose

To discuss the perioperative considerations and operative outcomes of 26 intravenous (i.v.) drug abusers who presented with infected false aneurysms of the limbs.

Methods

The subjects were 20 men and 6 women with pseudoaneurysms (mean age 34 years, range 19–53 years). The femoral and brachial arteries were most commonly involved. All patients, except for those with active bleeding, underwent digital subtraction angiography or Doppler ultrasonography, or both. Treatment consisted of excision and ligation of the aneurysm and local debridement, followed by revascularization with a vein graft or vein patch angioplasty.

Results

The presenting symptoms and signs included a pulsatile mass (69%), ischemic pain (23%), active bleeding (38.5%), signs of inflammation (61.5%), and positive blood culture (31%). Bleeding complications developed in two patients, who underwent subsequent extra-anatomic bypass. One of these patients had hip disarticulation and eventually died. None of the remaining patients had claudication or required an amputation. The mean follow-up period was 24 months (range: 3–50 months). Only five (19.2%) patients received drug rehabilitation, whereas the remaining patients admitted to continued drug abuse after discharge from hospital.

Conclusions

Limb salvage with immediate revascularization is safe and achieves functionality; therefore, its use is justified. Recidivism and continued abuse is the usual consequence after discharge from hospital, making recovery difficult.

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References

  1. GW Geelhoed WL Joseph (1974) ArticleTitleSurgical sequelae of drug abuse Surg Gynecol Obstet 139 749–55 Occurrence Handle4479694 Occurrence Handle1:STN:280:DyaE2M%2FkvV2ntA%3D%3D

    PubMed  CAS  Google Scholar 

  2. PR Benitez MA Newell (1986) ArticleTitleVascular trauma in drug abuse: patterns of injury Ann Vasc Surg 1 175–81 Occurrence Handle3504327 Occurrence Handle1:STN:280:DyaL1M%2Fmt1aksA%3D%3D

    PubMed  CAS  Google Scholar 

  3. RA Yeager RW Hobson Suffix2nd FT Padberg TG Lynch M Chakravarty (1987) ArticleTitleVascular complications related to drug abuse J Trauma 27 305–8 Occurrence Handle3560273 Occurrence Handle1:STN:280:DyaL2s7mvFymtQ%3D%3D Occurrence Handle10.1097/00005373-198703000-00014

    Article  PubMed  CAS  Google Scholar 

  4. GH Welch DB Reid JG Pollock (1990) ArticleTitleInfected false femoral aneurysms in the groin of intravenous drug abusers Br J Surg 77 330–3 Occurrence Handle2322803 Occurrence Handle10.1002/bjs.1800770331 Occurrence Handle1:STN:280:DyaK3c3htlWntg%3D%3D

    Article  PubMed  CAS  Google Scholar 

  5. N Levi P Rørdam LP Jensen TV Schroeder (1997) ArticleTitleFemoral pseudoaneurysms in drug addicts Eur J Vasc Endovasc Surg 13 361–2 Occurrence Handle9133986 Occurrence Handle10.1016/S1078-5884(97)80076-7 Occurrence Handle1:STN:280:DyaK2s3nvFGmtg%3D%3D

    Article  PubMed  CAS  Google Scholar 

  6. JP Gan DP Leiberman JG Pollock (2000) ArticleTitleOutcome after ligation of infected false femoral aneurysms in intravenous drug abusers Eur J Vasc Endovasc Surg 19 158–61 Occurrence Handle10727364 Occurrence Handle10.1053/ejvs.1999.0976 Occurrence Handle1:STN:280:DC%2BD3c7ptl2quw%3D%3D

    Article  PubMed  CAS  Google Scholar 

  7. PA Coughlin AI Mavor (2006) ArticleTitleArterial consequences of recreational drug use Eur J Vasc Endovasc Surg 32 389–96 Occurrence Handle16682239 Occurrence Handle10.1016/j.ejvs.2006.03.003 Occurrence Handle1:STN:280:DC%2BD28rltlyhtg%3D%3D

    Article  PubMed  CAS  Google Scholar 

  8. KR Patel L Semel RH Clauss (1988) ArticleTitleRoutine revascularization with resection of infected femoral pseudoaneurysms from substance abuse J Vasc Surg 8 321–8 Occurrence Handle3047444 Occurrence Handle10.1067/mva.1988.avs0080321 Occurrence Handle1:STN:280:DyaL1czjtlanuw%3D%3D

    Article  PubMed  CAS  Google Scholar 

  9. DJ Reddy RF Smith JP Elliott SuffixJr GK Haddad EA Wanek (1986) ArticleTitleInfected femoral artery false aneurysms in drug addicts: evolution of selective vascular reconstruction J Vasc Surg 3 718–24 Occurrence Handle3517387 Occurrence Handle10.1067/mva.1986.avs0030718 Occurrence Handle1:STN:280:DyaL283gtVCrsg%3D%3D

    Article  PubMed  CAS  Google Scholar 

  10. HC Huebl RC Read (1966) ArticleTitleAneurysmal abscess Minn Med 49 11–16 Occurrence Handle5901185 Occurrence Handle1:STN:280:DyaF28%2FmsFSlug%3D%3D

    PubMed  CAS  Google Scholar 

  11. S Arora MA Weber CJ Fox R Neville A Lidor AN Sidawy (2001) ArticleTitleCommon femoral artery ligation and local debridement: A safe treatment for infected femoral artery pseudoaneurysms J Vasc Surg 33 990–3 Occurrence Handle11331839 Occurrence Handle10.1067/mva.2001.114212 Occurrence Handle1:STN:280:DC%2BD3Mzis1SrtQ%3D%3D

    Article  PubMed  CAS  Google Scholar 

  12. ACW Ting SWK Cheng (1997) ArticleTitleFemoral pseudoaneurysms in drug addicts World J Surg 21 783–7 Occurrence Handle9327666 Occurrence Handle10.1007/s002689900306 Occurrence Handle1:STN:280:DyaK2svmvVGkuw%3D%3D

    Article  PubMed  CAS  Google Scholar 

  13. F Padberg SuffixJr R Hobson Suffix2nd B Lee R Anderson J Manno G Breitbart et al. (1992) ArticleTitleFemoral pseudoaneurysm from drugs of abuse: ligation or reconstruction? J Vasc Surg 15 642–8 Occurrence Handle1560553 Occurrence Handle10.1067/mva.1992.33731

    Article  PubMed  Google Scholar 

  14. SWK Cheng M Fok J Wong (1992) ArticleTitleInfected femoral pseudoaneurysm in intravenous drug abusers Br J Surg 79 510–12 Occurrence Handle1611440 Occurrence Handle10.1002/bjs.1800790611 Occurrence Handle1:STN:280:DyaK38zgsFyhsg%3D%3D

    Article  PubMed  CAS  Google Scholar 

  15. JR Johnson AM Ledgerwood CE Lucas (1983) ArticleTitleMycotic aneurysm. New concepts in therapy Arch Surg 118 577–82 Occurrence Handle6687676 Occurrence Handle1:STN:280:DyaL3s7nslGjug%3D%3D

    PubMed  CAS  Google Scholar 

  16. AJ Feldman R Berguer (1983) ArticleTitleManagement of an infected aneurysm of the groin secondary to drug abuse Surg Gynecol Obstet 157 519–22 Occurrence Handle6689089 Occurrence Handle1:STN:280:DyaL2c%2FntlKnuw%3D%3D

    PubMed  CAS  Google Scholar 

  17. AE Yellin (1977) ArticleTitleRuptured mycotic aneurysm: a complication of parenteral drug abuse Arch Surg 112 981–6 Occurrence Handle577679 Occurrence Handle1:STN:280:DyaE2s3itVyqtw%3D%3D

    PubMed  CAS  Google Scholar 

  18. SH Fromm CE Lucas (1970) ArticleTitleObturator bypass for mycotic aneurysm in the drug addict Arch Surg 100 82–3 Occurrence Handle5466898 Occurrence Handle1:STN:280:DyaE3c%2Fmt12lsg%3D%3D

    PubMed  CAS  Google Scholar 

  19. JW Tsao SR Marder J Goldstone AI Bloom (2002) ArticleTitlePresentation, diagnosis, and management of arterial mycotic pseudoaneurysms in injection drug users Ann Vasc Surg 16 652–62 Occurrence Handle12203000 Occurrence Handle10.1007/s10016-001-0124-6

    Article  PubMed  Google Scholar 

  20. SP Hopkins A Kazmers (2000) ArticleTitleManagement of vascular infections in the groin Ann Vasc Surg 14 532–9 Occurrence Handle10990569 Occurrence Handle10.1007/s100169910101 Occurrence Handle1:STN:280:DC%2BD3cvksFKisQ%3D%3D

    Article  PubMed  CAS  Google Scholar 

  21. ME Benjamin EJ Cohn SuffixJr WA Purtill DJ Hanna MP Lilly WR Flinn (1999) ArticleTitleArterial reconstruction with deep leg veins for the treatment of mycotic aneurysms J Vasc Surg 30 1004–15 Occurrence Handle10587384 Occurrence Handle10.1016/S0741-5214(99)70038-8 Occurrence Handle1:STN:280:DC%2BD3c%2FlsVKmtQ%3D%3D

    Article  PubMed  CAS  Google Scholar 

  22. YD Patel DB Norowitz (1988) ArticleTitleRuptured mycotic aneurysms Cardiovasc Intervent Radiol 11 86–90 Occurrence Handle3134137 Occurrence Handle10.1007/BF02577066 Occurrence Handle1:STN:280:DyaL1c3ntVCktw%3D%3D

    Article  PubMed  CAS  Google Scholar 

  23. RL Rodriguez RC Batson MD Kerstein (1985) Vascular injury associated with drug abuse MD Kerstein (Eds) Management of vascular trauma University Park Press Baltimore 108–19

    Google Scholar 

  24. WT Siu KK Yau HY Cheung BK Law CN Tang GP Yang et al. (2005) ArticleTitleManagement of brachial artery pseudoaneurysms secondary to drug abuse Ann Vasc Surg 19 657–61 Occurrence Handle16096861 Occurrence Handle10.1007/s10016-005-6836-2

    Article  PubMed  Google Scholar 

  25. RA Yegane NA Salehi A Ghaseminegad F Bahrami M Bashashati M Ahmadi et al. (2006) ArticleTitleSurgical approach to vascular complications of intravenous drug abuse Eur J Vasc Endovasc Surg 32 397–401 Occurrence Handle16616530 Occurrence Handle10.1016/j.ejvs.2006.02.014

    Article  PubMed  Google Scholar 

  26. SA Naqi HM Khan S Akhtar TA Shah (2006) ArticleTitleFemoral pseudoaneurysm in drug addicts-excision without revascularization is a viable option Eur J Vasc Endovasc Surg 31 585–7 Occurrence Handle16466941 Occurrence Handle10.1016/j.ejvs.2005.12.011 Occurrence Handle1:STN:280:DC%2BD28zjtVGlsw%3D%3D

    Article  PubMed  CAS  Google Scholar 

  27. P Patra JB Ricco A Costargent Y Goueffic JC Pillet P Chaillou et al. (2001) ArticleTitleInfected aneurysms of neck and limb arteries: a retrospective multicenter study Ann Vasc Surg 15 197–205 Occurrence Handle11265084 Occurrence Handle10.1007/s100160010047 Occurrence Handle1:STN:280:DC%2BD3M3lsFSgsg%3D%3D

    Article  PubMed  CAS  Google Scholar 

  28. PJ Walker GH White JP Harris KM Alle J May (1992) ArticleTitleBilateral mycotic axillary artery false aneurysms in an intravenous drug user: unsuspected broken needle-tips pose a risk to the treating personnel Eur J Vasc Surg 6 434–7 Occurrence Handle1499749 Occurrence Handle10.1016/S0950-821X(05)80295-6 Occurrence Handle1:STN:280:DyaK38zmt12jtw%3D%3D

    Article  PubMed  CAS  Google Scholar 

  29. GS Georgiadis MK Lazarides A Polychronidis C Simopoulos (2005) ArticleTitleSurgical treatment of femoral artery infected false aneurysms in drug abusers ANZ J Surg 75 1005–10 Occurrence Handle16336398 Occurrence Handle10.1111/j.1445-2197.2005.03578.x

    Article  PubMed  Google Scholar 

  30. DJ Reddy (2001) Femoral artery pseudoaneurysm from trauma JL Cronenwett RB Rutherford (Eds) Decision making in vascular surgery EditionNumber1st ed Saunders Philadelphia 142–5

    Google Scholar 

  31. NH Kumins DS Landau J Montalvo J Zasadzinski J Wojciechowski BD Jovanovich et al. (1998) ArticleTitleExpanded indications for the treatment of postcatheterization pseudoaneurysms with ultrasound-guided compression Am J Surg 176 131–6 Occurrence Handle9737617 Occurrence Handle10.1016/S0002-9610(98)00159-7 Occurrence Handle1:STN:280:DyaK1cvgslKgtw%3D%3D

    Article  PubMed  CAS  Google Scholar 

  32. KV Lambert P Hayes M McCarthy (2005) ArticleTitleVacuum assisted closure: a review of development and current applications Eur J Vasc Endovasc Surg 29 219–26 Occurrence Handle15694791 Occurrence Handle10.1016/j.ejvs.2004.12.017 Occurrence Handle1:STN:280:DC%2BD2M%2Fms1SntA%3D%3D

    Article  PubMed  CAS  Google Scholar 

  33. YC Chan KG Burnand (2006) ArticleTitleManagement of septic groin complications and infected femoral false aneurysms in intravenous drug abusers Br J Surg 93 781–2 Occurrence Handle16775821 Occurrence Handle10.1002/bjs.5452 Occurrence Handle1:STN:280:DC%2BD28znsVKisA%3D%3D

    Article  PubMed  CAS  Google Scholar 

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Georgiadis, G., Bessias, N., Pavlidis, P. et al. Infected False Aneurysms of the Limbs Secondary to Chronic Intravenous Drug Abuse: Analysis of Perioperative Considerations and Operative Outcomes. Surg Today 37, 837–844 (2007). https://doi.org/10.1007/s00595-006-3495-z

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  • DOI: https://doi.org/10.1007/s00595-006-3495-z

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