Abstract
Background
Heterotopic ossification (HO) is a pathologic bone formation in extra skeletal tissue and articular space. This was an objection to nailing of femur fractures across the knee; however, this has not been the case in many thousands of cases. Nonetheless, we present a patient in who placement of a retrograde nail resulted in calcification in the knee requiring excision.
Case presentation
A 42-year-old male presented to the clinic complaining of pain, popping, clicking, and mocking in the right knee, especially in the patellar region. Nine months prior he suffered an ipsilateral femur fracture that was treated with a retrograde intramedullary nail. X-ray and CT scan were used to confirm the presentation of a heterotopic bone mass in the Hoffa area of the right knee. The patient underwent an arthrotomy for excision of the bone mass. The bone mass was excised, but bone in the ACL was not removed. The patient experienced pain relief and improved range of motion following excision.
Conclusion
Intraarticular heterotopic ossification is an infrequent event. We present a case of heterotopic ossification in the knee following retrograde nailing. The patient experienced improved symptoms and range of motion after excision of the intraarticular heterotopic bone mass.
Similar content being viewed by others
References
Kaplan FS, Glaser DL, Hebela N, Shore EM (2004) Heterotopic ossification. JAAOS—J Am Acad Orthop Surg 12(2):116–125
Stannard JP, Wilson TC, Sheils TM, McGwin G, Volgas DA, Alonso JE (2002) Heterotopic ossification associated with knee dislocation. Arthroscopy 18(8):835–839. https://doi.org/10.1053/jars.2002.32842
Nauth A, Giles E, Potter BK et al (2012) Heterotopic ossification in orthopaedic trauma. J Orthop Trauma 26(12):684. https://doi.org/10.1097/BOT.0b013e3182724624
Forsberg JA, Pepek JM, Wagner S et al (2009) Heterotopic ossification in high-energy wartime extremity injuries: prevalence and risk factors. JBJS 91(5):1084–1091. https://doi.org/10.2106/JBJS.H.00792
Cipriano CA, Pill SG, Keenan MA (2009) Heterotopic ossification following traumatic brain injury and spinal cord injury. J Am Acad Orthop Surg 17(11):689–697. https://doi.org/10.5435/00124635-200911000-00003
Garland DE (1988) Clinical observations on fractures and heterotopic ossification in the spinal cord and traumatic brain injured populations. Clin Orthop Relat Res 233:86–101
Green SA (1988) Distal intramedullary fixation of supracondylar fractures of the femur. Tech Orthop 3(3):71–76
Ostrum RF (2003) Retrograde femoral nailing: indications and techniques. Oper Tech Orthop 13(2):79–84. https://doi.org/10.1053/otor.2003.0167
Iannacone WM, Bennett FS, DeLong WG, Born CT, Dalsey RM (1994) Initial experience with the treatment of supracondylar femoral fractures using the supracondylar intramedullary nail: a preliminary report. J Orthop Trauma 8(4):322–327. https://doi.org/10.1097/00005131-199408000-00008
Gregory P, DiCicco J, Karpik K, DiPasquale T, Herscovici D, Sanders R (1996) Ipsilateral fractures of the femur and tibia: treatment with retrograde femoral nailing and unreamed tibial nailing. J Orthop Trauma 10(5):309–316. https://doi.org/10.1097/00005131-199607000-00004
Lucas SE, Seligson D, Henry SL (1993) Intramedullary supracondylar nailing of femoral fractures. a preliminary report of the GSH supracondylar nail. Clin Orthop Relat Res 296:200–206
Firoozbakhsh K, Behzadi K, DeCoster TA, Moneim MS, Naraghi FF (1995) Mechanics of retrograde nail versus plate fixation for supracondylar femur fractures. J Orthop Trauma 9(2):152–157. https://doi.org/10.1097/00005131-199504000-00011
Harris LJ (1980) Closed retrograde intramedullary nailing of peritrochanteric fractures of the femur with a new nail. J Bone Joint Surg Am 62(7):1185–1193
Sanders R, Koval KJ, DiPasquale T, Helfet DL, Frankle M (1993) Retrograde reamed femoral nailing. J Orthop Trauma 7(4):293–302. https://doi.org/10.1097/00005131-199308000-00001
Patterson BM, Routt ML, Benirschke SK, Hansen ST (1995) Retrograde nailing of femoral shaft fractures. J Trauma 38(1):38–43. https://doi.org/10.1097/00005373-199501000-00012
Horne LT, Blue BA (1999) Intraarticular heterotopic ossification in the knee following intramedullary nailing of the fractured femur using a retrograde method. J Orthop Trauma 13(5):385–388. https://doi.org/10.1097/00005131-199906000-00013
Tan L, Wang T, Li YH et al (2017) Patellar tendon ossification after retrograde intramedullary nailing for distal femoral shaft fracture. Medicine (Baltimore) 96(47):e8875. https://doi.org/10.1097/MD.0000000000008875
Takemoto RC, Epstein D, McLaurin TM (2011) Intra- and periarticular heterotopic ossification in the knee after a low-velocity gunshot wound treated with retrograde intramedullary nailing of the femur. J Orthop Trauma 25(7):e77-82. https://doi.org/10.1097/BOT.0b013e3181f981e1
Kent WT, Shelton TJ, Eastman J (2018) Heterotopic ossification around the knee after tibial nailing and ipsilateral antegrade and retrograde femoral nailing in the treatment of floating knee injuries. Int Orthop 42(6):1379–1385. https://doi.org/10.1007/s00264-018-3845-7
Simonsen LL, Sonne-Holm S, Krasheninnikoff M, Engberg AW (2007) Symptomatic heterotopic ossification after very severe traumatic brain injury in 114 patients: incidence and risk factors. Injury 38(10):1146–1150. https://doi.org/10.1016/j.injury.2007.03.019
Tornetta P, Tiburzi D (2000) Antegrade or retrograde reamed femoral nailing. A prospective, randomised trial. J Bone Joint Surg Br Vol 82(5):652–654. https://doi.org/10.1302/0301-620x.82b5.10038
Fuller DA, Mark A, Keenan MAE (2005) Excision of heterotopic ossification from the knee: a functional outcome study. Clin Orthop Relat Res 438:197–203. https://doi.org/10.1097/00003086-200509000-00033
Mitsionis GI, Lykissas MG, Kalos N et al (2009) Functional outcome after excision of heterotopic ossification about the knee in ICU patients. Int Orthop 33(6):1619–1625. https://doi.org/10.1007/s00264-008-0618-8
Funding
No funding was received to assist with the preparation of this manuscript. No funding was received for conducting this study. No funds, grants, or other support was received.
Author information
Authors and Affiliations
Contributions
Dr. Davd Seligson, MD is a consultant for Stryker Trauma. Mr. Nadar has no disclosures. The authors did not receive support from any organization for the submitted work.
Corresponding author
Ethics declarations
Conflict of interest
The authors declare that they have no competing interests.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
About this article
Cite this article
Nadar, A.C., Seligson, D. Heterotopic ossification in the knee following retrograde nailing of a femur fracture. Eur J Orthop Surg Traumatol 33, 3181–3184 (2023). https://doi.org/10.1007/s00590-023-03491-4
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00590-023-03491-4