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Membranous nephropathy associated with familial chronic ulcerative colitis in a 12-year-old girl

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Abstract

Glomerulonephritis is a rare complication in patients with inflammatory bowel disease. We report a case of membranous nephropathy (MN) in a 12.6-year-old girl with chronic ulcerative colitis. The girl was referred to the hospital with bloody diarrhea and arthralgia. Routine urinalysis showed 1 g/m2 protein excretion in 24 h. Serum ANCA titers were positive. The diagnoses were confirmed by coloscopy and kidney biopsy. The patient’s mother had also suffered from ulcerative colitis in adolescence. Proteinuria normalized under treatment with prednisone (60 mg/m2/day) and azathioprine, which was initiated to treat the colitis. Chronic ulcerative colitis can be associated with glomerulonephritis.

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Author notes

  1. Nader Gordjani

    Present address: Kinderklinik, Städtisches Klinikum Offenbach, Offenbach, Germany

Authors and Affiliations

  1. Children’s Hospital, University of Würzburg, Josef Schneider Str. 2, 97080, Würzburg, Germany

    Regina M. Ridder, Hans W. Kreth & Nader Gordjani

  2. Deutsches Krebsforschungszentrum, Heidelberg, Germany

    Eva Kiss & Hermann J. Gröne

Authors
  1. Regina M. Ridder
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  2. Hans W. Kreth
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  3. Eva Kiss
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  4. Hermann J. Gröne
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  5. Nader Gordjani
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Corresponding author

Correspondence to Nader Gordjani.

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Ridder, R.M., Kreth, H.W., Kiss, E. et al. Membranous nephropathy associated with familial chronic ulcerative colitis in a 12-year-old girl. Pediatr Nephrol 20, 1349–1351 (2005). https://doi.org/10.1007/s00467-005-1986-6

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  • DOI: https://doi.org/10.1007/s00467-005-1986-6

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