Abstract
Purpose
Although professional societies agreed that CT screening inconsistent with recommendation leads to radiation-related cancer and unexpected cost, many patients still undergo unnecessary Chest CT before treatment. The goal of this study was to assess the overuse of Chest CT in different type of patients.
Methods
Data on 1853 patients who underwent pulmonary resection from May 2019 to May 2020 were retrospectively analyzed. Data collected include age, sex, follow-up period, density and size of nodules and frequency of undergoing Chest CT. Pearson χ2 test and logistic regression were conducted to compare the receipt of CT screening.
Results
Among 1853 patients in the study, 689 (37.2%) overused Chest CT during follow-up of the pulmonary nodules. This rate was 16.2% among patients with solid nodules, 57.5% among patients with pure ground glass opacity (pGGO), and 41.4% among patients with mixed ground glass opacity (mGGO) (P < 0.001). 50.7% in the “age ≤ 40” group, 39.8% in the “41 ≤ age ≤ 50” group, 38.7% in the “51 ≤ age ≤ 60” group, 32.3% in the “61 ≤ age ≤ 70” group, 27.8% in the “ > 70” group underwent unnecessary CT (P < 0.001). Female got more unnecessary CT than male (40.6% vs 32.8%, P < 0.001). Factors associated with a greater likelihood of overusing Chest CT was the density of nodules [odds ratios (ORs) of 0.53 for mGGO; 0.15 for solid nodule, P < 0.0001, vs patients with pGGO].
Conclusion
Roughly 37% patients with pulmonary nodules received Chest CT too frequently despite national recommendations against the practice. Closer adherence to clinical guidelines is likely to result in more cost-effective care.
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Data availability
All data and material is applicable.
Code availability
We used SPSS to analyze our data, and the software is applicable.
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Acknowledgements
This work was supported by the National Natural Science Foundation of China (81930073), Shanghai Science and Technology Innovation Action Project (20JC1417200), Shanghai Municipal Science and Technology Major Project (2017SHZDZX01, VBH1323001/026), Shanghai Municipal Key Clinical Specialty Project (SHSLCZDZK02104), and Pilot Project of Fudan University (IDF159045).
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Guo, R., Zhang, Y., Ma, Z. et al. Overuse of follow-up chest computed tomography in patients with incidentally identified nodules suspicious for lung cancer. J Cancer Res Clin Oncol 148, 1147–1152 (2022). https://doi.org/10.1007/s00432-021-03692-6
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DOI: https://doi.org/10.1007/s00432-021-03692-6