Abstract
Purpose
The effect of acute exhaustive exercise session on skin microvascular reactivity was assessed in professional rowers and sedentary subjects. A potential involvement of altered hemodynamic parameters and/or oxidative stress level in the regulation of skin microvascular blood flow by acute exercise were determined.
Methods
Anthropometric, biochemical, and hemodynamic parameters were measured in 18 young healthy sedentary men and 20 professional rowers who underwent a single acute exercise session. Post-occlusive reactive hyperemia (PORH), endothelium-dependent acetylcholine (ACh), and endothelium-independent sodium nitroprusside (SNP) microvascular responses were assessed by laser Doppler flowmetry in skin microcirculation before and after acute exercise. Serum lipid peroxidation products and plasma antioxidant capacity were measured using spectrophotometry.
Results
At baseline, rowers had significantly lower diastolic blood pressure (DBP) and heart rate (HR), and higher stroke volume (SV), PORH, and endothelium-dependent vasodilation than sedentary. Acute exercise caused a significant increase in systolic blood pressure, DBP, HR, and SV and a decrease in total peripheral resistance in both groups. Acute exercise induced a significant impairment in PORH and ACh-induced response in rowers, but not in sedentary, whereas the SNP-induced vasodilation was not affected by acute exercise in any group. Antioxidant capacity significantly increased only in sedentary after acute exercise.
Conclusion
Single acute exercise session impaired microvascular reactivity and endothelial function in rowers but not in sedentary, possibly due to (1) more rowing grades and higher exercise intensity achieved by rowers; (2) a higher increase in arterial pressure in rowers than in sedentary men; and (3) a lower antioxidant capacity in rowers.
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Abbreviations
- ACh:
-
Acetylcholine
- AE:
-
Acute exercise
- ApoA:
-
Apolipoprotein A
- ApoB:
-
Apolipoprotein B
- AUC:
-
Area under the curve
- BMI:
-
Body mass index
- BP:
-
Blood pressure
- CO:
-
Cardiac output
- CV:
-
Cardiovascular
- DBP:
-
Diastolic blood pressure
- ECW%:
-
Extracellular water%
- FBC:
-
Full blood cell count
- FFM%:
-
Fat free mass%
- FM%:
-
Fat mass%
- FMD:
-
Flow-mediated dilation
- FRAP:
-
Ferric-reducing ability of plasma
- HDL:
-
High-density lipoprotein cholesterol
- HR:
-
Heart rate
- hsCRP:
-
High-sensitivity C-reactive protein
- ICG:
-
Impedance cardiography
- ICW%:
-
Intracellular water%
- LDF:
-
Laser Doppler flowmetry
- LDL:
-
Low-density lipoprotein cholesterol
- MAP:
-
Mean arterial pressure
- MDA:
-
Malondialdehyde
- NO:
-
Nitric oxide
- PORH:
-
Post-occlusive reactive hyperemia
- RE:
-
Regular exercise
- RPE:
-
Rating of perceived exertion
- SBP:
-
Systolic blood pressure
- SD:
-
Standard deviation
- SNP:
-
Sodium nitroprusside
- SV:
-
Stroke volume
- TBARS:
-
Thiobarbituric acid reactive substances
- TBW%:
-
Total body water%
- TPR:
-
Total peripheral resistance
- WHR:
-
Waist-to-hip ratio
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Acknowledgements
We thank to Rowing Club Iktus Osijek and Croatian Rowing Club Vukovar for engagement in this study.
Funding
This study was supported by earmarked funding grant of Faculty of Medicine Josip Juraj Strossmayer University of Osijek VIF2015-MEFOS-05 “Mechanisms involved in endothelial dysfunction development by acute high salt loading and acute exhausting exercise”; and Osijek-Baranja County project (2014–2016) “Influence of exercise on cardiovascular physiological parameters”.
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Communicated by Carsten Lundby.
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Stupin, M., Stupin, A., Rasic, L. et al. Acute exhaustive rowing exercise reduces skin microvascular dilator function in young adult rowing athletes. Eur J Appl Physiol 118, 461–474 (2018). https://doi.org/10.1007/s00421-017-3790-y
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DOI: https://doi.org/10.1007/s00421-017-3790-y