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Four-year to seven-year outcomes of advanced surface ablation with excimer laser for high myopia

  • Refractive Surgery
  • Published:
Graefe's Archive for Clinical and Experimental Ophthalmology Aims and scope Submit manuscript

Abstract

Purpose

We aimed to evaluate and compare outcomes after photorefractive keratectomy with cooling (cPRK) and laser-assisted subepithelial keratectomy (LASEK) for high myopia.

Methods

This was a retrospective, single-masked follow-up study of patients treated for myopia between 2007 and 2009 with cPRK or LASEK, using a high-frequency flying-spot excimer laser with eye-tracker (MEL80; Carl Zeiss, Jena, Germany). One eye of each patient was randomly chosen for analysis. Re-treated eyes were excluded.

Results

Forty-six cPRK patients and 35 LASEK patients were included. Spherical equivalent averaged −7.69 ± 1.47 diopters (D) in cPRK eyes and −7.98 ± 2.06 D in LASEK eyes (p = 0.31) before surgery. The average follow-up time was 4.6 years in cPRK patients and 6.0 years in LASEK patients (p < 0.05). At final follow-up, no cPRK eyes and one LASEK eye (p = 0.46) had lost two lines of corrected distance visual acuity (CDVA). No eyes had significant haze at final follow-up, although trace haze was found in four cPRK eyes and six LASEK eyes (p = 0.44). However, at 6 weeks after surgery, zero cPRK eyes and nine LASEK eyes (p < 0.05) had significant haze. At final follow-up, 63 % of cPRK eyes and 35 % of LASEK eyes (p = 0.17) were within ±1.0 D of intended refraction. Finally, 100 % of cPRK patients and 92 % of LASEK patients (p = 0.87) were satisfied or very satisfied with the surgery at final follow-up.

Conclusion

cPRK and LASEK seemed safe and with high patient satisfaction 4 to 7 years after surgery for high myopia. However, cPRK was more effective than LASEK in reducing initial significant corneal haze.

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Acknowledgments

This work was supported by Odense University Hospital Research Foundation, the Synoptik Foundation, Goldsmith A. L. & D. Rasmussen’s Foundation, and Ingemann O. Buck’s Foundation.

Conflict of interest

The authors have no financial or proprietary interest in the materials presented herein.

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Authors and Affiliations

  1. Department of Ophthalmology, Odense University Hospital, Sdr. Boulevard 29, 5000, Odense C, Denmark

    Rasmus Søgaard Hansen, Niels Lyhne, Jakob Grauslund, Keea Treu Grønbech & Anders Højslet Vestergaard

  2. Institute of Clinical Research, University of Southern Denmark, Odense, Denmark

    Rasmus Søgaard Hansen, Niels Lyhne, Jakob Grauslund, Keea Treu Grønbech & Anders Højslet Vestergaard

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  1. Rasmus Søgaard Hansen
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  2. Niels Lyhne
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Correspondence to Rasmus Søgaard Hansen.

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Hansen, R.S., Lyhne, N., Grauslund, J. et al. Four-year to seven-year outcomes of advanced surface ablation with excimer laser for high myopia. Graefes Arch Clin Exp Ophthalmol 253, 1027–1033 (2015). https://doi.org/10.1007/s00417-014-2920-z

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  • DOI: https://doi.org/10.1007/s00417-014-2920-z

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