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Detection of cholesteatoma: 2D BLADE turbo gradient- and spin-echo imaging versus readout-segmented echo-planar diffusion-weighted imaging

  • Rhinology
  • Published:
European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

Purpose

This study is to compare the accuracy of 2D BLADE turbo gradient- and spin-echo imaging (TGSE BLADE) diffusion-weighted imaging (DWI) with that of readout-segmented echo-planar (RESOLVE) DWI in the detection of primary and residual/recurrent temporal bone cholesteatoma.

Methods

The prospective study population consisted of 58 patients who were underwent magnetic resonance (MR) imaging for the evaluation of suspected temporal bone cholesteatoma. Two radiologists independently evaluated the two sequences. Kappa (k) statistics, the intra-class correlation coefficient (ICC), and a paired t test were used for statistical analysis.

Results

Of the 58 patients included, all had histo-pathologically confirmed cholesteatomas. In ≤ 3 mm group (n = 13), TGSE BLADE sequence correctly identified all cases except one that was recorded as equivocal on both sequences because of high signal intensity on T1WI; while on RESOLVE sequences, 6 were positive, 4 were equivocal, and 3 were false negative. For > 3 mm group (n = 45), detection performance was similar between the two sequences. The mean ADC of cholesteatoma on TGSE BLADE DWI was 0.923 × 10–3 mm2/s, and the mean ADC of cholesteatoma on RESOLVE DWI was 0.949 × 10–3 mm2/s, with no significant difference in the mean ADC values of cholesteatoma measured on the two sequences (p = 0.9216).

Conclusion

TGSE BLADE outperforms RESOLVE in the detection of small temporal bone cholesteatoma ≤ 3 mm.

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Availability of data and material

The authors declare that the data are available.

Code availability

The authors declare that the custom code can be available.

Abbreviations

TGSE BLADE:

2D BLADE turbo gradient- and spin-echo imaging

RESOLVE:

Readout-segmented echo-planar imaging

DWI:

Diffusion-weighted imaging

MRI:

Magnetic resonance imaging

Non-EPI:

Non-echo-planar imaging

SS-EPI:

Single-shot echo-planar imaging

SNR:

Signal-to-noise ratio

HRCT:

High-resolution computed tomography

T1WI:

T1-weighted imaging

T2WI-FS:

T2-weighted fat-suppression imaging

ADC:

Apparent diffusion coefficient

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Author notes

  1. Mengyan Lin and Naier Lin should be considered co-first authors.

Authors and Affiliations

  1. Shanghai Institute of Medical Imaging, Shanghai, 200032, China

    Mengyan Lin

  2. Department of Radiology, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, China

    Mengyan Lin, Naier Lin, Yaru Sheng & Yan Sha

  3. Scientific Marketing, Siemens Healthcare, Shanghai, 200336, China

    Zhongshuai Zhang & Kun Zhou

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  1. Mengyan Lin
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Corresponding author

Correspondence to Yan Sha.

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This study was approved by the institutional review board of our university hospital and written consent was obtained from each patient.

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Lin, M., Lin, N., Sheng, Y. et al. Detection of cholesteatoma: 2D BLADE turbo gradient- and spin-echo imaging versus readout-segmented echo-planar diffusion-weighted imaging. Eur Arch Otorhinolaryngol 279, 5223–5229 (2022). https://doi.org/10.1007/s00405-022-07370-2

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  • DOI: https://doi.org/10.1007/s00405-022-07370-2

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