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26 August 2019
In the original article publication, the authors given name and family name were interchanged.
References
Brunello J, Guerby P, Cartoux C, Yazigi A, Baujat M, Parant O et al (2019) Can early βhCG change and baseline progesterone level predict treatment outcome in patients receiving single dose Methotrexate protocol for tubal ectopic pregnancy? Arch Gynecol Obstet 299(3):741–745
Hajenius PJ, Engelsbel S, Mol BJW, Van der Veen F, Ankum WM, Bossuyt PMM et al (1997) Randomised trial of systemic methotrexate versus laparoscopic salpingostomy in tubal pregnancy. Lancet 350:774–779
Stovall TG, Ling FW (1993) Single-dose methotrexate: an expanded clinical trial. Am J Obstet Gynecol 168:1759–1765
Corsan GH, Karacan M, Qasim S, Bohrer MK, Ransom MX, Kemmann E (1995) Identification of hormonal parameters for successful systemic single-dose methotrexate therapy in ectopic pregnancy. Hum Reprod 10:2719–2722
Barnhart K, Coutifaris C, Esposito M (2001) The pharmacology of methotrexate. Expert Opin Pharmacother. 2(3):409–417
Committee on Practice Bulletin-Gynecology (2018) ACOG practice bulletin No. 191: tubal ectopic pregnancy. Obstet Gynecol 131(2):e65–e77
Marret H, Fauconnier A, Dubernard G, Misme H, Lagarce L, Lesavre M et al (2016) Overview and guidelines of off-label use of methotrexate in ectopic pregnancy: report by CNGOF. Eur J Obstet Gynecol Reprod Biol. 205:105–109
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Brunello, J., Guerby, P., Cartoux, C. et al. Safety considerations regarding Methotrexate off-label use in tubal ectopic pregnancy. Arch Gynecol Obstet 300, 1095–1096 (2019). https://doi.org/10.1007/s00404-019-05254-1
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DOI: https://doi.org/10.1007/s00404-019-05254-1