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Irritable bowel syndrome and interstitial cystitis/bladder pain syndrome are associated with pruritus bidirectionally in U.S. adults

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Data availability

Data may be made available upon reasonable request to the corresponding author.

Abbreviations

Irritable bowel syndrome:

(IBS)

Interstitial cystitis:

(IC)

The International Classification of Diseases:

(ICD)

Odds ratio:

(OR)

Confidence interval:

(CI)

References

  1. Ekiz Ö, Balta İ, Özuğuz P, Şen BB, Rifaioğlu EN, Ekiz F, Yüksel İ, Çoban Ş, Başar Ö (2014) Irritable bowel syndrome in patients with chronic pruritus of undetermined origin. J Eur Acad Dermatol Venereol 28(8):1034–1039. https://doi.org/10.1111/jdv.12251

    Article  CAS  PubMed  Google Scholar 

  2. Lee KN, Lee OY (2016) The role of mast cells in irritable bowel syndrome. Gastroenterol Res Pract 2016:2031480. https://doi.org/10.1155/2016/2031480

    Article  PubMed  PubMed Central  Google Scholar 

  3. Sant GR, Kempuraj D, Marchand JE, Theoharides TC (2007) The mast cell in interstitial cystitis: role in pathophysiology and pathogenesis. Urology 69(4):S34–S40. https://doi.org/10.1016/j.urology.2006.08.1109

    Article  Google Scholar 

  4. Wang X, Liu W, O’Donnell M, Lutgendorf S, Bradley C, Schrepf A, Liu L, Kreder K, Luo Y (2016) Evidence for the role of mast cells in cystitis-associated lower urinary tract dysfunction: a multidisciplinary approach to the study of chronic pelvic pain research network animal model study. PLoS ONE 11(12):e0168772-e. https://doi.org/10.1371/journal.pone.0168772

    Article  CAS  Google Scholar 

  5. Yosipovitch G, Bernhard JD (2013) Chronic pruritus. N Engl J Med 368(17):1625–1634. https://doi.org/10.1056/NEJMcp1208814

    Article  CAS  PubMed  Google Scholar 

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Acknowledgements

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Authors and Affiliations

Authors

Contributions

SAC: Investigation; Writing – Original Draft; Writing – Review & Editing. ADP: Formal Analysis; Investigation; Writing – Review & Editing; Resources. JCDR: Formal Analysis. BSK: Methodology; Writing – Review & Editing. BU: Conceptualization; Methodology; Writing – Review & Editing; Supervision.

Corresponding author

Correspondence to Benjamin Ungar.

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Conflict of interest

BU is an employee of Mount Sinai and has received research funds (grants paid to the institution) from Incyte, Rapt Therapeutics, and Pfizer. He is also a consultant for Arcutis Biotherapeutics, Castle Biosciences, Fresenius Kabi, Pfizer, and Sanofi. BSK is an employee of Mount Sinai. He also has received personal fees from AbbVie, Argenx, Abrax, Japan, Almirall, S.A., Amagma, Amgen, Bristol-Myers Squibb, Cara Therapeutics, Eli Lilly and Company, Evommune, Escient Pharmaceuticals, Galderma S.A., GlaxoSmithKline, Genzyme, Granular Therapeutics, Guidepoint Global, Incyte Corporation, Janssen Pharmaceuticals, Inc., LEO Pharma, Pfizer Inc., Novartis, Recens Medical, Regeneron, and Trevi Therapeutics. JCDR is an employee of Mount Sinai. The rest of the authors declare no relevant conflicts of interest.

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Caldas, S., Pagan, A.D., Correa da Rosa, J. et al. Irritable bowel syndrome and interstitial cystitis/bladder pain syndrome are associated with pruritus bidirectionally in U.S. adults. Arch Dermatol Res 315, 2745–2747 (2023). https://doi.org/10.1007/s00403-023-02684-5

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  • DOI: https://doi.org/10.1007/s00403-023-02684-5

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