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Primary anastomosis with diverting loop ileostomy versus Hartmann’s procedure for acute complicated diverticulitis: analysis of the National Inpatient Sample 2015–2019

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Abstract

Background

Up to 50% of patients with acute complicated diverticulitis require operative management on their index admission. There is ongoing debate as to whether primary anastomosis with diverting ileostomy versus a Hartmann’s procedure is the optimal surgical approach for these patients. This study aims to compare postoperative complications in patients undergoing either Hartmann’s procedure or primary anastomosis and diverting ileostomy for perforated diverticulitis using recent National Inpatient Sample data.

Methods

Patients who underwent either primary anastomosis with diverting ileostomy or Hartmann’s procedure for acute complicated diverticulitis from the 2015 to 2019 NIS database sample were included. Primary outcomes were postoperative in-hospital mortality and morbidity. Secondary outcomes were postoperative cause-specific complications, total admission cost, and length of stay (LOS). Univariate and multivariate regression were utilized to compare the two operative approaches.

Results

Overall, 642 patients underwent primary anastomosis with diverting ileostomy and 4,482 patients underwent Hartmann’s procedure. There was no difference in in-hospital mortality (OR 0.93, 95%CI 0.45–1.92, p = 0.84) or in-hospital morbidity (OR 1.10, 95%CI 0.90–1.35, p = 0.33). Adjusted analysis suggested shorter postoperative LOS for patients undergoing Hartmann’s procedure (MD 0.79 days, 95%CI 0.15–1.43 days, p = 0.013) and decreased total admission cost (MD $4,893.99, 95%CI $1,425.04-$8,362.94, p = 0.006).

Conclusions

The present study supports that primary anastomosis with diverting ileostomy is safe for properly selected patients presenting with complicated diverticulitis. Primary anastomosis with diverting ileostomy is associated with greater total hospitalization costs and LOS.

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Data availability

The data used in the current study is available upon request.

References

  1. Tursi A, Scarpignato C, Strate LL et al (2020) Colonic diverticular disease. Nat Rev Dis Primers 2020 6:1 6:1–23. https://doi.org/10.1038/s41572-020-0153-5

  2. Tursi A (2016) Diverticulosis today: unfashionable and still under-researched. Therap Adv Gastroenterol 9:213. https://doi.org/10.1177/1756283X15621228

    Article  PubMed  PubMed Central  Google Scholar 

  3. Bollom A, Austrie J, Hirsch W et al (2017) Emergency Department Burden of Diverticulitis in the United States, 2006 to 2013. Dig Dis Sci 62:2694. https://doi.org/10.1007/S10620-017-4525-Y

    Article  PubMed  PubMed Central  Google Scholar 

  4. Shahedi K, Fuller G, Bolus R et al (2013) Long-term Risk of Acute Diverticulitis Among Patients With Incidental Diverticulosis Found During Colonoscopy. Clin Gastroenterol Hepatol 11:1609. https://doi.org/10.1016/J.CGH.2013.06.020

    Article  PubMed  PubMed Central  Google Scholar 

  5. von Strauss Und Torney M, Moffa G, Kaech M et al (2020) Risk of Emergency Surgery or Death After Initial Nonoperative Management of Complicated Diverticulitis in Scotland and Switzerland. JAMA Surg 155:600–606. https://doi.org/10.1001/JAMASURG.2020.0757

    Article  PubMed  Google Scholar 

  6. Bharucha AE, Parthasarathy G, Ditah I et al (2015) Temporal Trends in the Incidence and Natural History of Diverticulitis: A Population-Based Study. Am J Gastroenterol 110:1589. https://doi.org/10.1038/AJG.2015.302

    Article  PubMed  PubMed Central  Google Scholar 

  7. Oberkofler CE, Rickenbacher A, Raptis DA et al (2012) A multicenter randomized clinical trial of primary anastomosis or Hartmann’s procedure for perforated left colonic diverticulitis with purulent or fecal peritonitis. Ann Surg 256:819–827. https://doi.org/10.1097/SLA.0B013E31827324BA

    Article  PubMed  Google Scholar 

  8. Nunes GC, Robnett AH, Kremer RM, Ahlquist RE (1979) The Hartmann Procedure for Complications of Diverticulitis. Arch Surg 114:425–429. https://doi.org/10.1001/ARCHSURG.1979.01370280079011

    Article  CAS  PubMed  Google Scholar 

  9. Hallam S, Mothe BS, Tirumulaju RMR (2018) Hartmann’s procedure, reversal and rate of stoma-free survival. Ann R Coll Surg Engl 100:301. https://doi.org/10.1308/RCSANN.2018.0006

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Bridoux V, Regimbeau JM, Ouaissi M et al (2017) Hartmann’s Procedure or Primary Anastomosis for Generalized Peritonitis due to Perforated Diverticulitis: A Prospective Multicenter Randomized Trial (DIVERTI). J Am Coll Surg 225:798–805. https://doi.org/10.1016/J.JAMCOLLSURG.2017.09.004

    Article  PubMed  Google Scholar 

  11. Lambrichts DPV, Vennix S, Musters GD et al (2019) Hartmann’s procedure versus sigmoidectomy with primary anastomosis for perforated diverticulitis with purulent or faecal peritonitis (LADIES): a multicentre, parallel-group, randomised, open-label, superiority trial. Lancet Gastroenterol Hepatol 4:599–610. https://doi.org/10.1016/S2468-1253(19)30174-8

    Article  PubMed  Google Scholar 

  12. Lee JM, Chang BP, J, el Hechi M et al (2019) Hartmann’s Procedure vs Primary Anastomosis with Diverting Loop Ileostomy for Acute Diverticulitis: Nationwide Analysis of 2,729 Emergency Surgery Patients. J Am Coll Surg 229:48–55. https://doi.org/10.1016/J.JAMCOLLSURG.2019.03.007

    Article  PubMed  Google Scholar 

  13. Goldstone RN, Cauley CE, Chang DC et al (2019) The Effect of Surgical Training and Operative Approach on Outcomes in Acute Diverticulitis: Should Guidelines Be Revised? Dis Colon Rectum 62:71–78. https://doi.org/10.1097/DCR.0000000000001240

    Article  PubMed  Google Scholar 

  14. Cauley CE, Patel R, Bordeianou L (2018) Use of primary anastomosis with diverting ileostomy in patients with acute diverticulitis requiring urgent operative intervention. Dis Colon Rectum 61:586–592. https://doi.org/10.1097/DCR.0000000000001080

    Article  PubMed  Google Scholar 

  15. Tadlock MD, Karamanos E, Skiada D et al (2013) Emergency surgery for acute diverticulitis: Which operation? A national surgical quality improvement program study. J Trauma Acute Care Surg 74:1385–1391. https://doi.org/10.1097/TA.0B013E3182924A82

    Article  PubMed  Google Scholar 

  16. HCUP-US NIS Overview. https://www.hcup-us.ahrq.gov/nisoverview.jsp. Accessed 28 Oct 2022

  17. Wei D, Johnston S, Goldstein L, Nagle D (2019) Minimally invasive colectomy is associated with reduced risk of anastomotic leak and other major perioperative complications and reduced hospital resource utilization as compared with open surgery: a retrospective population-based study of comparative effectiveness and trends of surgical approach. Surg Endosc 34(2):610–621. https://doi.org/10.1007/S00464-019-06805-Y

  18. Kang CY, Halabi WJ, Chaudhry OO et al (2013) Risk Factors for Anastomotic Leakage After Anterior Resection for Rectal Cancer. JAMA Surg 148:65–71. https://doi.org/10.1001/2013.JAMASURG.2

    Article  PubMed  Google Scholar 

  19. Gawlick U, Nirula R (2012) Resection and primary anastomosis with proximal diversion instead of Hartmann’s: evolving the management of diverticulitis using NSQIP data. J Trauma Acute Care Surg 72:807–814. https://doi.org/10.1097/TA.0B013E31824EF90B

    Article  PubMed  Google Scholar 

  20. Binda GA, Karas JR, Serventi A et al (2012) Primary anastomosis vs nonrestorative resection for perforated diverticulitis with peritonitis: a prematurely terminated randomized controlled trial. Colorectal Dis 14:1403–1410. https://doi.org/10.1111/J.1463-1318.2012.03117.X

    Article  CAS  PubMed  Google Scholar 

  21. Hall J, Hardiman K, Lee S et al (2020) The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Treatment of Left-Sided Colonic Diverticulitis. Dis Colon Rectum 63:728–747. https://doi.org/10.1097/DCR.0000000000001679

    Article  PubMed  Google Scholar 

  22. Sartelli M, Weber DG, Kluger Y et al (2020) 2020 update of the WSES guidelines for the management of acute colonic diverticulitis in the emergency setting. World J Emergency Surg 15:1–18. https://doi.org/10.1186/S13017-020-00313-4

  23. Epstein AM (1995) US Teaching Hospitals in the Evolving Health Care System. JAMA 273:1203–1207. https://doi.org/10.1001/JAMA.1995.03520390063034

    Article  CAS  PubMed  Google Scholar 

  24. Onald D, Aylor HT, Avid D et al (1999) Effects of Admission to a Teaching Hospital on the Cost and Quality of Care for Medicare Beneficiaries. 340:293–299. https://doi.org/10.1056/NEJM199901283400408

  25. Khuri SF, Najjar SF, Daley J et al (2001) Comparison of surgical outcomes between teaching and nonteaching hospitals in the Department of Veterans Affairs. Ann Surg 234:370–383. https://doi.org/10.1097/00000658-200109000-00011

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  26. Sutton E, Miyagaki H, Bellini G et al (2017) Risk factors for superficial surgical site infection after elective rectal cancer resection: a multivariate analysis of 8880 patients from the American College of Surgeons National Surgical Quality Improvement Program database. J Surg Res 207:205–214. https://doi.org/10.1016/J.JSS.2016.08.082

    Article  PubMed  Google Scholar 

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Contributions

All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by Yung Lee and Tyler McKechnie. The first draft of the manuscript was written by Yung Lee, and Tyler McKechnie. Yasith Samarasinghe prepared Tables 1, 2, 3 and 4 and Appendix 1, and all authors edited and commented on previous versions of the manuscript. All authors read and approved the final manuscript.

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Correspondence to Dennis Hong.

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Lee, Y., McKechnie, T., Samarasinghe, Y. et al. Primary anastomosis with diverting loop ileostomy versus Hartmann’s procedure for acute complicated diverticulitis: analysis of the National Inpatient Sample 2015–2019. Int J Colorectal Dis 38, 156 (2023). https://doi.org/10.1007/s00384-023-04452-3

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