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The evaluation of GI-pill gastrointestinal electronic capsule for colonic transit test in patients with slow transit constipation

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International Journal of Colorectal Disease Aims and scope Submit manuscript

Abstract

Objective

The evaluation of GI-pill gastrointestinal electronic capsule for colonic transit test in patients with slow transit constipation (STC) was studied.

Materials and methods

STC patients (n = 162) were randomly divided into experimental group (n = 84, orally taken GI-pill gastrointestinal electronic capsule and X-ray granule capsule) and control group (n = 78, orally taken X-ray granule capsule). Comparison of the time in colonic transit test between the two groups was conducted. The data of GI-pill gastrointestinal electronic capsule in vivo time, time of capsule passing through the colon, the number of high amplitude propagating contractions (HAPCs), and physiological response ratio were analyzed.

Results

There were no significant differences in the whole colonic transit test time, right colonic transit time, left colonic transit time, and rectosigmoid colonic transit time between experimental group and control group (p > 0.05). All patients had no abdominal pain, nausea, vomiting, black stool, difficulty in electronic capsule excretion, or any other discomfort during the test.

Conclusion

GI-pill gastrointestinal electronic capsule can continuously evaluate the dynamic characteristics of digestive tract in STC patients and is consistent with X-ray granule capsule, which is meaningful to clinical application.

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Financial support

This study was supported by Key Disciplines ConstructionProject of Pudong Health Bureau of Shanghai (No. PWZxk2017–11) and Science and Technology Development Fund of Shanghai Pudong New Area (No. PKJ2018-Y10).

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Authors and Affiliations

  1. Department of General Surgery, Shanghai University of Medicine & Health Sciences Affiliated Pudong New District People’s Hospital, Shanghai, 201299, China

    Yong-bing Wang, Gang Li, Yun-feng Wang & Yu-jiang Ding

  2. Institute of Precise Engineering and Intelligent Microsystems, Shanghai Jiaotong University, Shanghai, 200240, China

    Guo-zheng Yan, Ding Han & Zhi-wu Wang

  3. Clinical Medical School, Shanghai University of Medicine & Health Sciences, 279 Zhouzhu Road, Shanghai, 201318, People’s Republic of China

    Xiao-hui Zhao

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  1. Yong-bing Wang
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  2. Gang Li
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  3. Yun-feng Wang
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  5. Guo-zheng Yan
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Correspondence to Xiao-hui Zhao.

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Wang, Yb., Li, G., Wang, Yf. et al. The evaluation of GI-pill gastrointestinal electronic capsule for colonic transit test in patients with slow transit constipation. Int J Colorectal Dis 35, 29–34 (2020). https://doi.org/10.1007/s00384-019-03422-y

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  • DOI: https://doi.org/10.1007/s00384-019-03422-y

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