Abstract
To evaluate the utility of imaging-guided fine-needle percutaneous biopsy of renal masses, we conducted a prospective analysis of our imaging-guided procedures from January 1999 to February 2003. We performed 54 percutaneous core biopsies in 46 patients. Fluoro-computed tomography and ultrasound guidance were respectively used in 48 and six cases. One to four specimens were obtained by using an 18-gauge automated coaxial biopsy system. We reviewed the patients medical records, pathology results, and imaging studies. Core biopsy results were compared with surgical pathology (n=27) or clinical follow-up (n=19). All biopsies provided sufficient material for analysis. The mean tumor size was 33 mm. Biopsy findings were positive for malignancy in 31 cases; histologic diagnoses included renal cell carcinoma (n=23), transitional cell carcinoma (n=5), and metastasis (n=3). Biopsy revealed 15 benign diagnoses: oncocytoma (n=6), hemorrhagic renal cyst (n=3), chronic nephritis (n=3), angiomyolipoma (n=2), and mycotic renal abscess (n=1). The average follow-up period for patients with benign diagnoses was 16 months. Biopsy results showed normal renal parenchyma in eight of 54 procedures, all of which had recuperated by subsequent biopsies. No immediate complications occurred after the procedures. Imaging-guided percutaneous core biopsy is a safe and accurate method for the evaluation of renal masses.
Similar content being viewed by others
References
Greenlee RT, Murray T, Bolden S, Wingo PA (2000) Cancer statistics, 2000. CA Cancer J Clin 50(1):7–33
Jayson M, Sanders H (1998) Increased incidence of serendipitously discovered renal cell carcinoma. Urology 51(2):203–205
Chow WH, Devesa SS, Warren JL, Fraumeni JF Jr (1999) Rising incidence of renal cell cancer in the United States. JAMA 281(17):1628–1631
Uzzo RG, Novick AC (2001) Nephron sparing surgery for renal tumors: indications, techniques and outcomes. J Urol 166(1):6–18
Fuhrman SA, Lasky LC, Limas C (1982) Prognostic significance of morphologic parameters in renal cell carcinoma. Am J Surg Pathol 6(7):655–663
Bretheau D, Lechevallier E, Fromont M de, et al (1995) Prognostic value of nuclear grade of renal cell carcinoma. Cancer 76(12):2543–2549
Russo P (2000) Evolving understanding and surgical management of renal cortical tumors. Mayo Clin Proc 75(12):1233–1235
Nativ O, Sabo E, Raviv G, et al (1997) The impact of tumor size on clinical outcome in patients with localized renal cell carcinoma treated by radical nephrectomy. J Urol 158(3 Pt 1):729–732
Wood BJ, Khan MA, McGovern F, et al (1999) Imaging guided biopsy of renal masses: indications, accuracy and impact on clinical management. J Urol 161(5):1470–1474
Tang S, Li JH, Lui SL, et al (2002) Free-hand, ultrasound-guided percutaneous renal biopsy: experience from a single operator. Eur J Radiol 41(1):65–69
Szekely JG, Villanyi K, Battyany I (1998) Technical aspects of percutaneous renal biopsy now. Nephron 79(1):106
Siegel CL (2001) Accuracy of diagnosis by guided biopsy of renal mass lesions classified indeterminate by imaging studies. J Urol 165(1):322–323
Richter F, Kasabian NG, Irwin RJ Jr, Watson RA, Lang EK (2000) Accuracy of diagnosis by guided biopsy of renal mass lesions classified indeterminate by imaging studies. Urology 55(3):348–352
Mignon F, Mesurolle B, Ariche-Cohen M, Vanel D (2001) Value of CT guided renal biopsies: retrospective review of 67 cases. J Radiol 82(8):907–911
Lechevallier E, Andre M, Barriol D et al (2000) Fine-needle percutaneous biopsy of renal masses with helical CT guidance. Radiology 216(2):506–510
Caoili EM, Bude RO, Higgins EJ, Hoff DL, Nghiem HV (2002) Evaluation of sonographically guided percutaneous core biopsy of renal masses. Am J Roentgenol 179(2):373–378
Herts BR, Coll DM, Novick AC, et al (2002) Enhancement characteristics of papillary renal neoplasms revealed on triphasic helical CT of the kidneys. Am J Roentgenol 178(2):367–372
Korbet SM (2002) Percutaneous renal biopsy. Semin Nephrol 22(3):254–267
Herts BR, Baker ME (1995) The current role of percutaneous biopsy in the evaluation of renal masses. Semin Urol Oncol 13(4):254–261
Danis D, Pauer M, Slugen I, et al (1996) Diagnosis of renal tumors with percutaneous biopsy. Bratisl Lek L 97(1):43–45
Khajehdehi P, Junaid SM, Salinas-Madrigal L, Schmitz PG, Bastani B (1999) Percutaneous renal biopsy in the 1990s: safety, value, and implications for early hospital discharge. Am J Kidney Dis 34(1):92–97
Dechet CB, Zincke H, Sebo TJ, et al (2003) Prospective analysis of computerized tomography and needle biopsy with permanent sectioning to determine the nature of solid renal masses in adults. J Urol 169(1):71–74
Prakash J, Singh M, Tripathi K, Rai US (1994) Complications of percutaneous renal biopsy. J Indian Med Assoc 92(12):395–396
Aimino M, Francisco M, Garnieri G, et al (2001) Percutaneous renal biopsy with a semi-automate device. Minerva Urol Nefrol 53(2):65–67
Goethuys H, Van Poppel H, Oyen R, Baert L (1996) The case against fine-needle aspiration cytology for small solid kidney tumors. Eur Urol 29(3):284–287
Preda A, Van Dijk LC, Van Oostaijen J, et al (2003) Complication rate and diagnostic yield of 515 consecutive ultrasound-guided biopsies of renal allografts and native kidneys using a 14-gauge Biopty gun. Eur Radiol 13(3):527–530
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Jaff, A., Molinié, V., Mellot, F. et al. Evaluation of imaging-guided fine-needle percutaneous biopsy of renal masses. Eur Radiol 15, 1721–1726 (2005). https://doi.org/10.1007/s00330-004-2577-9
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00330-004-2577-9