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Magnetic resonance imaging of pituitary adenomas

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Abstract

Today, MR is the only method needed for the morphological investigation of endocrine-active pituitary adenomas. In acromegaly and Cushing’s syndrome, the therapeutic attitude is directly dictated by MR data. We present the MR aspect of pituitary adenomas according to size, sex, age, endocrine activity and a few particular conditions such as hemorrhagic pituitary adenomas, pituitary adenomas during pregnancy, cavernous sinus invasion and postsurgical changes. When an intrasellar mass extending out of the sella turcica is detected, the goal of the MR examination is to indicate precisely the origin of the tumor, its extension in relation to the various surrounding structures, its structure and its enhancement in order to help in the differential diagnosis. Demonstration of very small pituitary adenomas remains a challenge. When SE T1- and Turbo SE T2-weighted sequences are non-diagnostic, enhanced imaging becomes mandatory; half-dose gadolinium injection, delayed sequence, dynamic imaging can be of some help.

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References

  1. Ahmadi J, North CM, Segall HD, Zee CS, Weiss MH (1986) Cavernous sinus invasion by pituitary adenomas. Am J Roentgenol 146:257–262

    CAS  Google Scholar 

  2. Bonneville JF, Cattin F, Gorczyca W, Hardy J (1993) Pituitary microadenomas: early enhancement with dynamic CT-implications of arterial blood supply and potential importance. Radiology 187:857–861

    CAS  PubMed  Google Scholar 

  3. Brismon MH (1996) Symptoms of pituitary apoplexy rapidly reversed with bromocriptine. Case report. J Neurosurg 85:1153–1155

    PubMed  Google Scholar 

  4. Colombo N, Loli P, Vignati F, Scialfa G (1994) MR of corticotropin-secreting pituitary microadenomas. Am J Neuroradiol 15:1591–1595

    CAS  PubMed  Google Scholar 

  5. Davis PC, Hoffman JC Jr, Spencer T et al (1987) MR Imaging of pituitary adenoma: CT, clinical and surgical correlation. Am J Roentgenol 148:797–802

    CAS  Google Scholar 

  6. Davis PC, Hoffman JC Jr, Malko JA et al (1987) Gadolinium-DTPA and MR imaging of pituitary adenoma: a preliminary report. Am J Neuroradiol 8:817–823

    CAS  PubMed  Google Scholar 

  7. Davis PC, Gokhale KA, Josep GJ (1991) Pituitary adenoma: correlation of half dose gadolinium enhanced MRI with surgical findings in 26 patients. Radiology 180:779–784

    CAS  PubMed  Google Scholar 

  8. Davis PC, Hoffman JC Jr, Spencer T, Tindall GT, Braun IF (1987) MR Imaging of pituitary adenoma: CT, clinical, and surgical correlation. Am J Roentgenol 148:797–802

    CAS  Google Scholar 

  9. Dietemann JL, Portha C, Cattin F, Mollet E, Bonneville JF (1983) CT Follow-up of microprolactinomas during bromocriptine-induced pregnancy. Neuroradiology 25:133–138

    Article  CAS  PubMed  Google Scholar 

  10. Doppman JL, Frank JA, Dwyer AJ et al (1988) Gadolinium DTPA enhanced MR imaging of ACTH-secreting microadenomas of the pituitary gland. J Comput Assist Tomogr 12:728–735

    CAS  PubMed  Google Scholar 

  11. El Gammal T, Brooks BS (1989) MR imaging of the ectopic bright signal of posterior pituitary regeneration. Am J Neuroradiol 10:323–328

    CAS  PubMed  Google Scholar 

  12. Elster AD (1993) Modern imaging of pituitary. Radiology 187:1–14

    Google Scholar 

  13. Knosp E, Kitz K, Steiner E, Matula CH (1991) Pituitary adenomas with parasellar invasion. Acta Neurochir 53:65–71

    CAS  Google Scholar 

  14. Kucharczyk W, Davis DO, Kelly WM, Sze G, Norman D, Newton TH (1986) Pituitary adenomas: high-resolution MR imaging at 1.5 T. Radiology 161:761–765

    CAS  PubMed  Google Scholar 

  15. Kucharczyk W, Bishop JE, Plewes DB, Keller MA, George S (1994) Detection of pituitary microadenomas: comparison of dynamic keyhole fast spin-echo, unenhanced, and conventional contrast-enhanced MR imaging. Am J Neuroradiol 15:671–679

    Google Scholar 

  16. Lundin P, Bergström K, Nyman R, Lundberg PO, Muhr C (1992) Macroprolactinomas: serial MR imaging in long term bromocriptine therapy. Am J Neuroradiol 13:1279–1291

    CAS  PubMed  Google Scholar 

  17. Lundin P (1997) Long-term octreotide therapy in growth hormone-secreting pituitary adenomas: evaluation with serial MR. Am J Neuroradiol 18:765–772

    CAS  PubMed  Google Scholar 

  18. Scotti G, Yu CY, Dillon WP et al (1988) MR imaging of cavernous sinus involvement by pituitary adenomas. Am J Neuroradiol 9:657–664

    Google Scholar 

  19. Steiner E, Knosp E, Herold CJ et al (1992) Pituitary adenomas: findings of postoperative MR imaging. Radiology 185:521–527

    CAS  PubMed  Google Scholar 

  20. Teng MM, Huang C, Chang T (1988) The pituitary mass after transsphenoidal hypophysectomy. Am J Neuroradiol 9:23–26

    Google Scholar 

  21. Youssem DM, Arrington JA, Zinreich SJ, Kumar AJ, Bryan RN (1989) Pituitary adenomas: possible role of bromocriptine in intratumoral hemorrhage. Radiology 170:239–243

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Neuroradiology, University Hospital, CHU Jean Minjoz, 3 Bd A. Fleming, 25030, Besançon Cedex, France

    Jean-François Bonneville, Fabrice Bonneville & Françoise Cattin

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  1. Jean-François Bonneville
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  2. Fabrice Bonneville
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  3. Françoise Cattin
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Correspondence to Jean-François Bonneville.

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Bonneville, JF., Bonneville, F. & Cattin, F. Magnetic resonance imaging of pituitary adenomas. Eur Radiol 15, 543–548 (2005). https://doi.org/10.1007/s00330-004-2531-x

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  • DOI: https://doi.org/10.1007/s00330-004-2531-x

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