Skip to main content

Advertisement

Log in

Pseudo-Behçet’s disease associated with tuberculosis: a case report and review of the literature

  • Short Communication
  • Published:
Rheumatology International Aims and scope Submit manuscript

Abstract

Orogenital ulcer is one of the clinical manifestations of Behçet’s disease (BD). However, orogenital ulcer may be observed in various conditions, such as complex aphthous dermatitis and herpes simplex virus infections. Therefore, orogenital ulcer along with skin lesions, including acne or erythema nodosum, may be misdiagnosed as BD, but is actually pseudo-BD instead. We report here a case of pseudo-BD due to Mycobacterium tuberculosis infection in which anti-tuberculous treatment resulted in complete resolution. Furthermore, we review the literature regarding the association of BD and M. tuberculosis infection.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

References

  1. Rueda JC, Crepy MF, Mantilla RD (2013) Clinical features of Poncet’s disease. From the description of 198 cases found in the literature. Clin Rheumatol 32:929–935

    Article  PubMed  Google Scholar 

  2. Barbagallo J, Tager P, Ingleton R, Hirsch RJ, Weinberg JM (2002) Cutaneous tuberculosis: diagnosis and treatment. Am J Clin Dermatol 3:319–328

    Article  PubMed  Google Scholar 

  3. Mendes D, Correia M, Barbedo M, Vaio T, Mota M, Gonçalves O, Valente J (2009) Behçet’s disease-a contemporary review. J Autoimmunol 32:178–188

    Article  CAS  Google Scholar 

  4. Rogers RS 3rd (2003) Pseudo-Behçet’s disease. Dermatol Clin 21:49–61

    Article  PubMed  Google Scholar 

  5. Ambrose NL, Haskard DO (2013) Differential diagnosis and management of Behçet syndrome. Nat Rev Rheumatol 9:79–89

    Article  PubMed  CAS  Google Scholar 

  6. Sharma A, Dogra S, Pinto B, Sharma K, Singh R, Dhir V, Sharma SK, Kakkar N, Radotra B, Singh S (2013) Poncet’s disease presenting as pseudo-Behçet’s disease. Int J Rheum Dis 16:483–485

    Article  PubMed  Google Scholar 

  7. Hamill M, Remedios D, Kapembwa M (2006) Orogenital ulceration with overlapping tuberculosis: epiphenomenon or expanding spectrum of Behçet disease? J Low Genit Tract Dis 10:219–222

    Article  PubMed  Google Scholar 

  8. Efthimiou J, Hay PE, Spiro SG, Lane DJ (1988) Pulmonary tuberculosis in Behçet’s syndrome. Br J Dis Chest 82:300–304

    Article  PubMed  CAS  Google Scholar 

  9. Coelho PC, da Silva JA, Romeu JC, da Costa JC, de Queiroz MV (1994) Simultaneous appearance of Behçet’s disease and pulmonary tuberculosis. Clin Exp Rheumatol 12:692

    PubMed  CAS  Google Scholar 

  10. Cho S, Lee KJ, Lee JD, Bang D, Cho SB (2011) Detection of tuberculous lymphadenopathy by positron emission tomography/computed tomography in a patient with Behçet’s disease. Acta Derm Venereol 91:470–471

    Article  PubMed  Google Scholar 

  11. Kroot EJA, Hazes JMW, Colin EM, Dolhain JEM (2007) Poncet’s disease: reactive arthritis accompanying tuberculosis. Two case reports and a review of the literature. Rheumatology 46:484–489

    Article  PubMed  CAS  Google Scholar 

  12. Direskeneli H (2013) Innate and adaptive responses to heat shock proteins in Behcet’s disease. Genet Res Int. doi:10.1155/2013/249157

    PubMed  PubMed Central  Google Scholar 

Download references

Conflict of interest

There is no financial support or other benefits from commercial sources for the work reported on in the manuscript, or no other financial interests that any of the authors may have, which could create a potential conflict of interest or the appearance of a conflict of interest with regard to the work.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Hirofumi Taki.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Shinoda, K., Hayashi, R., Taki, H. et al. Pseudo-Behçet’s disease associated with tuberculosis: a case report and review of the literature. Rheumatol Int 34, 1471–1474 (2014). https://doi.org/10.1007/s00296-014-2998-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00296-014-2998-y

Keywords

Navigation