Abstract
Complex regional pain syndrome type I (CRPS I) or reflex sympathetic dystrophy (RSD) is a painful and disabling neuropathic pain syndrome. We report a case of a patient who has experienced CRPS I four times with an unidentified cause for all recurrences. The patient responded well to a combination of physiotherapy and intravenous regional sympathetic block in the first two attacks, but not in the fourth one. Gabapentin was effective in the last two attacks. Gabapentin was gradually discontinued 12 months after the last attack and no other recurrence was observed for a follow-up period of 9 months. This case suggests that gabapentin might be considered in the treatment and prevention of CRPS I.
References
Kasdan ML, Johnson AL (1998) Reflex sympathetic dystrophy. Occup Med 13:521–531
Mellick GA, Mellick LB (1997) Reflex sympathetic dystrophy treated with gabapentin. Arch Phys Med Rehabil 78:98–105
Tong HC, Nelson VS (2001) Recurrent and migratory reflex sympathetic dystrophy in children. Pediatr Rehabil 4(2):87–89
Marx C, Wiedersheim P, Michel BA, Stucki G (2001) Preventing recurrence of reflex sympathetic dystrophy in patients requiring an operative intervention at the site of dystrophy after surgery. Clin Rheumatol 20:114–118
Munn JS, Baker WH (1987) Recurrent sympathetic dystrophy: successful treatment by contralateral sympathectomy. Surgery 102(1):102–105
Merskey H, Bogduk N (1994) Classification of chronic pain: descriptions of chronic pain syndromes and definitions of pain terms, 2nd edn. IASP Press, Seattle
Zollinger PE, Tuinebreijer WE, Kreis RW, Breederveld RS (1999) Effect of vitamin C on frequency of reflex sympathetic dystrophy in wrist fractures: a randomized trial. Lancet 354(9195):2025–2028
Viel E, Ripart J, Pelissier J, Eledjam JJ (1999) Management of reflex sympathetic dystrophy. Ann Med Interne (Paris) 150(3):205–210
Foot M, Wallace J (1991) Gabapentin. Epilepsy Res Suppl 3:109–114
Forouzanfar T, Köke AJA, van Kleef M, Weber WEJ (2002) Treatment of complex regional pain syndrome type I. Eur J Pain 6(2):105–122
Berger JJ (2004) Amenorrhea in a patient after treatment with gabapentin for complex regional pain syndrome type II. Clin J Pain 20(3):192–194
Kumbhat S, Meyer N, Schur MJ (2004) Complex regional pain syndrome as a complication of chemical burn to the foot. J Burn Care Rehabil 25(2):189–191
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Akkus, S., Yorgancigil, H. & Yener, M. A case of recurrent and migratory complex regional pain syndrome type I: prevention by gabapentin. Rheumatol Int 26, 852–854 (2006). https://doi.org/10.1007/s00296-005-0090-3
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DOI: https://doi.org/10.1007/s00296-005-0090-3