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Morphologische Variabilität des synovialen Sarkoms im Kindesalter

Morphological variability of synovial sarcoma in childhood

  • Schwerpunkt: Weichgewebstumoren
  • Published:
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Zusammenfassung

Vorgestellt werden die histologischen Befunde eines rezidivierenden plantaren Weichgewebesarkoms eines 7-jährigen Jungen. Der Primärtumor konnte aufgrund seiner ungewöhnlichen Morphologie initial nicht exakt klassifiziert werden. Die Diagnosestellung eines synovialen Sarkoms gelang erst am morphologisch deutlich differenten Tumorrezidiv in der Synopsis der histomorphologischen, ultrastrukturellen, immunhistochemischen und molekularbiologischen Befunde. Der Fall verdeutlicht das histomorphologische Spektrum synovialer Sarkome und den Stellenwert moderner Diagnostik für die Tumorklassifikation.

Abstract

We report on an unusual locally recurrent plantar soft tissue sarcoma in a 7-years-old boy. Due to an unusual morphology a clear diagnosis was initially not possible. The histologically different recurrent tumor was classified as synovial sarcoma by means of immunohistochemistry, ultrastructural and molecular analysis. This case demonstrates the variable morphological appearence of synovial sarcoma and the value of modern diagnostic procedures in such circumstances.

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Authors and Affiliations

  1. Institut für Pathologie der Martin-Luther-Universität Halle-Wittenberg

    C. Taege, H.-J. Holzhausen & S. Hauptmann

  2. Institut für Paidopathologie der Christian-Albrechts-Universität Kiel

    D. Harms

  3. Institut für Pathologie der Friedrich-Schiller-Universität Jena

    D. Katenkamp

  4. Klinik für Kinderchirurgie des St. Barbara Krankenhauses Halle

    G. Guenther

  5. Institut für Pathologie der Martin-Luther-Universität Halle-Wittenberg, Magdeburger Str. 14, 06097, Halle/Saale

    C. Taege

Authors
  1. C. Taege
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  2. H.-J. Holzhausen
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  3. D. Harms
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  4. D. Katenkamp
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  5. G. Guenther
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  6. S. Hauptmann
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Correspondence to C. Taege.

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Taege, C., Holzhausen, HJ., Harms, D. et al. Morphologische Variabilität des synovialen Sarkoms im Kindesalter. Pathologe 26, 159–162 (2005). https://doi.org/10.1007/s00292-004-0746-x

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  • DOI: https://doi.org/10.1007/s00292-004-0746-x

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