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3D heterometallic complex: photocatalytic property and preventive effect on osteoporosis by activating wnt signaling pathway

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Abstract

A new 3D structural compound, namely {[Cd2Sr(pdc)3(H2O)3]}n·n(DMF) (1, H2pdc = 1,4-benzenedicarboxylic acid, DMF = N,N′-dimethylformamide), has been produced with the raw materials of Cd(NO3)2·4H2O, Sr(NO3)2 and H2pdc under solvothermal conditions. Under an irradiation of UV light, 1a displayed outstanding photocatalytic effect for the organic dyes degradation of methylene orange (MO), Rhodamine B (RhB) and methylene blue (MB). In the biological section, the preventive effect and mechanism of new compound on osteoporosis was evaluated and explored. The activation of the FoxO/Wnt pathway in the primary osteoblast was firstly measured with real-time RT-PCR. The accumulation of ROS in the primary osteoblast was also determined with Reactive Oxygen Species Assay Kit.

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Data availability

Selected bond lengths (Å) and angles (°) for 1 (Table S1), the coordination modes of pdc2− ligand in 1 (a) (κ1κ1)-(κ2κ2)-μ5 (b) (κ2κ1)-(κ2κ1)-μ4 (Fig. S1), the information could be found in the supporting information file.

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Correspondence to Tao Li.

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Zhao, R., Li, T. 3D heterometallic complex: photocatalytic property and preventive effect on osteoporosis by activating wnt signaling pathway. Polym. Bull. 80, 11225–11234 (2023). https://doi.org/10.1007/s00289-022-04605-4

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