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Successful use of thrombopoietin analogs in thrombocytopenia associated with MYH-9 mutation

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References

  1. Kim B (2022) Diagnostic workup of inherited platelet disorders. Blood Res 57(S1):11–19

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Nurden P, Stritt S, Favier R, Nurden AT (2021) Inherited platelet diseases with normal platelet count: phenotypes, genotypes and diagnostic strategy. Haematologica 106(2):337–350

    Article  CAS  PubMed  Google Scholar 

  3. Pecci A, Ma X, Savoia A, Adelstein RS (2018) MYH9: structure, functions and role of non-muscle myosin IIA in human disease. Gene 664:152–167

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Paciullo F, Bury L, Gresele P (2020) Eltrombopag to allow chemotherapy in a patient with MYH9-related inherited thrombocytopenia and pancreatic cancer. Int J Hematol 112(5):725–727

    Article  PubMed  Google Scholar 

  5. Lassandro G, Carriero F, Noviello D, Palladino V, Del Vecchio GC, Faienza MF et al (2022) Successful eltrombopag therapy in a child with MYH9-related inherited thrombocytopenia. Children 9(12):1839

    Article  PubMed  PubMed Central  Google Scholar 

  6. Favier R, Feriel J, Favier M, Denoyelle F, Martignetti JA (2013) First successful use of eltrombopag before surgery in a child with MYH9-related thrombocytopenia. Pediatrics 132:e793–e795

    Article  PubMed  Google Scholar 

  7. Pecci A, Gresele P, Klersy C, Savoia A, Noris P, Fierro T et al (2010) Eltrombopag for the treatment of the inherited thrombocytopenia deriving from MYH9 mutations. Blood 116(26):5832–5837

    Article  CAS  PubMed  Google Scholar 

  8. Pecci A, Canobbio I, Balduini A, Stefanini L, Cisterna B, Marseglia C et al (2005) Pathogenetic mechanisms of hematological abnormalities of patients with MYH9 mutations. Hum Mol Genet 14:3169–3178

    Article  CAS  PubMed  Google Scholar 

  9. Bury L, Megy K, Stephens JC, Grassi L, Greene D, Gleadall N et al (2020) Next-generation sequencing for the diagnosis of MYH9-RD: predicting pathogenic variants. Human Mutat 41:277–290

    Article  CAS  Google Scholar 

  10. Pecci A, Panza E, Pujol-Moix N, Klersy C, Di Bari F, Bozzi V et al (2008) Position of nonmuscle myosin heavy chain IIA (NMMHC-IIA) mutations predicts the natural history of MYH9-related disease. Hum Mutat 29:409–417

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Hematology Department, Hospital Universitario Virgen del Rocio, Instituto de Biomedicina de Sevilla, Seville, Spain

    María Louzao, María Teresa Vargas, Emma Meseguer, Begoña Pedrote Amador, Jose Antonio Perez Simón & María Eva Mingot-Castellano

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  1. María Louzao
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  2. María Teresa Vargas
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  3. Emma Meseguer
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  4. Begoña Pedrote Amador
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  5. Jose Antonio Perez Simón
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  6. María Eva Mingot-Castellano
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Contributions

ML, MTV, and MEMC have designed and written the short report. The rest of authors have contributed to patient diagnosis and treatment. All authors have reviewed and validated the document.

Corresponding author

Correspondence to María Eva Mingot-Castellano.

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This article does not contain any studies with human participants performed by any of the authors.

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Informed consent was obtained from patient to publish information related with his clinical data.

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The authors declare no competing interests.

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Louzao, M., Vargas, M.T., Meseguer, E. et al. Successful use of thrombopoietin analogs in thrombocytopenia associated with MYH-9 mutation. Ann Hematol 102, 3283–3284 (2023). https://doi.org/10.1007/s00277-023-05386-0

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  • DOI: https://doi.org/10.1007/s00277-023-05386-0

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