Skip to main content
Log in

Oral beclomethasone dipropionate as an initial treatment for stages 1–2 gastrointestinal tract acute graft-versus-host disease following unrelated cord blood transplantation

  • Letter to the Editor
  • Published:
Annals of Hematology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. McDonald GB (2007) Oral beclomethasone dipropionate: a topically active corticosteroid for the treatment of gastrointestinal graft-versus-host disease following allogeneic hematopoietic cell transplantation. Expert Opin Investig Drugs 16(10):1709–1724

    Article  CAS  PubMed  Google Scholar 

  2. Ibrahim RB, Abidi MH, Cronin SM, Lum LG, Al-Kadhimi Z, Ratanatharathorn V, Uberti JP (2009) Nonabsorbable corticosteroids use in the treatment of gastrointestinal graft-versus-host disease. Biol Blood Marrow Transplant 15(4):395–405

    Article  CAS  PubMed  Google Scholar 

  3. McDonald GB, Bouvier M, Hockenbery DM, Stern JM, Gooley T, Farrand A, Murakami C, Levine DS (1998) Oral beclomethasone dipropionate for treatment of intestinal graft-versus-host disease: a randomized, controlled trial. Gastroenterology 115(1):28–35

    Article  CAS  PubMed  Google Scholar 

  4. Hockenbery DM, Cruickshank S, Rodell TC, Gooley T, Schuening F, Rowley S, David D, Brunvand M, Berryman B, Abhyankar S, Bouvier M, McDonald GB (2007) A randomized, placebo-controlled trial of oral beclomethasone dipropionate as a prednisone-sparing therapy for gastrointestinal graft-versus-host disease. Blood 109(10):4557–4563

    Article  CAS  PubMed  Google Scholar 

  5. Castilla C, Perez-Simon JA, Sanchez-Guijo FM, Diez-Campelo M, Ocio E, Perez-Persona E, Lopez-Villar O, Vazquez L, Caballero D, San Miguel JF (2006) Oral beclomethasone dipropionate for the treatment of gastrointestinal acute graft-versus-host disease (GVHD). Biol Blood Marrow Transplant 12(9):936–941

    Article  CAS  PubMed  Google Scholar 

  6. Miura Y, Narimatsu H, Kami M, Kusumi E, Matsumura T, Yuji K, Wake A, Miyakoshi S, Taniguchi S (2006) Oral beclomethasone dipropionate as an initial treatment of gastrointestinal acute graft-versus-host disease after reduced-intensity cord blood transplantation. Bone Marrow Transplant 38(8):577–579

    Article  CAS  PubMed  Google Scholar 

  7. Weisdorf D, Haake R, Blazar B, Miller W, McGlave P, Ramsay N, Kersey J, Filipovich A (1990) Treatment of moderate/severe acute graft-versus-host disease after allogeneic bone marrow transplantation: an analysis of clinical risk features and outcome. Blood 75(4):1024–1030

    CAS  PubMed  Google Scholar 

  8. MacMillan ML, Weisdorf DJ, Wagner JE, DeFor TE, Burns LJ, Ramsay NK, Davies SM, Blazar BR (2002) Response of 443 patients to steroids as primary therapy for acute graft-versus-host disease: comparison of grading systems. Biol Blood Marrow Transplant 8(7):387–394

    Article  CAS  PubMed  Google Scholar 

  9. Martin PJ, Schoch G, Fisher L, Byers V, Anasetti C, Appelbaum FR, Beatty PG, Doney K, McDonald GB, Sanders JE et al (1990) A retrospective analysis of therapy for acute graft-versus-host disease: initial treatment. Blood 76(8):1464–1472

    CAS  PubMed  Google Scholar 

Download references

Acknowledgments

The authors would like to thank data coordinators Kaori Kobayashi, Madoka Narita, Rumiko Tsuchihashi, and Naomi Yamada for their invaluable assistance. The authors would also like to thank the physicians, nurses, pharmacists, and support personnel for their care of patients in this study.

Conflict of interest

The authors declare that they have no conflict of interest.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Naoyuki Uchida.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Yamamoto, H., Uchida, N., Uchida, Y. et al. Oral beclomethasone dipropionate as an initial treatment for stages 1–2 gastrointestinal tract acute graft-versus-host disease following unrelated cord blood transplantation. Ann Hematol 94, 2073–2075 (2015). https://doi.org/10.1007/s00277-015-2483-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00277-015-2483-z

Keywords

Navigation