References
McDonald GB (2007) Oral beclomethasone dipropionate: a topically active corticosteroid for the treatment of gastrointestinal graft-versus-host disease following allogeneic hematopoietic cell transplantation. Expert Opin Investig Drugs 16(10):1709–1724
Ibrahim RB, Abidi MH, Cronin SM, Lum LG, Al-Kadhimi Z, Ratanatharathorn V, Uberti JP (2009) Nonabsorbable corticosteroids use in the treatment of gastrointestinal graft-versus-host disease. Biol Blood Marrow Transplant 15(4):395–405
McDonald GB, Bouvier M, Hockenbery DM, Stern JM, Gooley T, Farrand A, Murakami C, Levine DS (1998) Oral beclomethasone dipropionate for treatment of intestinal graft-versus-host disease: a randomized, controlled trial. Gastroenterology 115(1):28–35
Hockenbery DM, Cruickshank S, Rodell TC, Gooley T, Schuening F, Rowley S, David D, Brunvand M, Berryman B, Abhyankar S, Bouvier M, McDonald GB (2007) A randomized, placebo-controlled trial of oral beclomethasone dipropionate as a prednisone-sparing therapy for gastrointestinal graft-versus-host disease. Blood 109(10):4557–4563
Castilla C, Perez-Simon JA, Sanchez-Guijo FM, Diez-Campelo M, Ocio E, Perez-Persona E, Lopez-Villar O, Vazquez L, Caballero D, San Miguel JF (2006) Oral beclomethasone dipropionate for the treatment of gastrointestinal acute graft-versus-host disease (GVHD). Biol Blood Marrow Transplant 12(9):936–941
Miura Y, Narimatsu H, Kami M, Kusumi E, Matsumura T, Yuji K, Wake A, Miyakoshi S, Taniguchi S (2006) Oral beclomethasone dipropionate as an initial treatment of gastrointestinal acute graft-versus-host disease after reduced-intensity cord blood transplantation. Bone Marrow Transplant 38(8):577–579
Weisdorf D, Haake R, Blazar B, Miller W, McGlave P, Ramsay N, Kersey J, Filipovich A (1990) Treatment of moderate/severe acute graft-versus-host disease after allogeneic bone marrow transplantation: an analysis of clinical risk features and outcome. Blood 75(4):1024–1030
MacMillan ML, Weisdorf DJ, Wagner JE, DeFor TE, Burns LJ, Ramsay NK, Davies SM, Blazar BR (2002) Response of 443 patients to steroids as primary therapy for acute graft-versus-host disease: comparison of grading systems. Biol Blood Marrow Transplant 8(7):387–394
Martin PJ, Schoch G, Fisher L, Byers V, Anasetti C, Appelbaum FR, Beatty PG, Doney K, McDonald GB, Sanders JE et al (1990) A retrospective analysis of therapy for acute graft-versus-host disease: initial treatment. Blood 76(8):1464–1472
Acknowledgments
The authors would like to thank data coordinators Kaori Kobayashi, Madoka Narita, Rumiko Tsuchihashi, and Naomi Yamada for their invaluable assistance. The authors would also like to thank the physicians, nurses, pharmacists, and support personnel for their care of patients in this study.
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The authors declare that they have no conflict of interest.
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Yamamoto, H., Uchida, N., Uchida, Y. et al. Oral beclomethasone dipropionate as an initial treatment for stages 1–2 gastrointestinal tract acute graft-versus-host disease following unrelated cord blood transplantation. Ann Hematol 94, 2073–2075 (2015). https://doi.org/10.1007/s00277-015-2483-z
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DOI: https://doi.org/10.1007/s00277-015-2483-z