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Comparison of Bronchial Artery Embolisation Versus Conservative Treatment for Bronchiectasis-Related Nonmassive Haemoptysis: A Single-Centre Retrospective Study

  • Clinical Investigation
  • Embolisation (arterial)
  • Published:
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Abstract

Objective

To compare the safety and effectiveness between bronchial artery embolisation (BAE) and conservative treatment for bronchiectasis-related nonmassive haemoptysis patients.

Materials and Methods

From January 2015 to December 2020, consecutive bronchiectasis-related nonmassive haemoptysis patients who underwent either BAE (n = 98) or conservative treatment (n = 118) were included. Treatment-related complications, length of hospital stays, clinical success rate, patient satisfaction, and recurrence-free survival rates were compared between groups. Prognostic factors related to recurrence were also analysed.

Results

During a median follow-up time of 44.8 months (range, 2.4–83.6 months), 34 and 66 patients in the BAE and conservative treatment groups suffered relapse. The 1-year, 2-year, 3-year and 5-year haemoptysis-free survival rates in the BAE and conservative treatment groups were 79.2%, 68.1%, 62.8%, and 57.6% and 64.0%, 52.8%, 44.1%, and 37.0%, respectively (P = 0.007). The minor complication rate after BAE was higher than that after conservative treatment (23/98 vs. 12/118, P = 0.008). BAE was associated with shorter hospital stays (5.0 vs. 7.0 days, P = 0.042) and higher patient satisfaction (88.8% vs. 74.6%, P = 0.008) than those for conservative treatment and with comparable clinical success rates (95.9% vs. 91.5%, P = 0.192). Treatment type, haemoptysis duration, and bronchiectasis severity were independently significant predictors of recurrence for these patients.

Conclusions

BAE could be another option for bronchiectasis-related nonmassive haemoptysis patients. In the patients with longer duration and more severe bronchiectasis, BAE still appeared to have better long-term haemoptysis control than conservative therapy.

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Funding

This study was funded by Jiangsu Province’s Key Talents Program (QNRC2016559 to Qing-Quan Zu) and Construction Program of Jiangsu Province Clinical Research Center Support System (BL2014084 to Qing-Quan Zu).

Author information

Author notes

  1. Hai-Tao Yan and Guang-Dong Lu have contributed equally as first author to this study.

Authors and Affiliations

  1. Department of Interventional Radiology, The First Affiliated Hospital With Nanjing Medical University, Nanjing, 210029, China

    Hai-Tao Yan, Guang-Dong Lu, Jin-Xing Zhang, Chun-Gao Zhou, Sheng Liu, Hai-Bin Shi & Qing-Quan Zu

  2. Department of Clinical Medicine Research Institution, The First Affiliated Hospital With Nanjing Medical University, No. 300 Guangzhou Road, Nanjing, 210029, China

    Jin Liu

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  1. Hai-Tao Yan
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Correspondence to Qing-Quan Zu.

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Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional (Ethical review no. 2018-SR-097) and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. For this retrospective study, formal consent was not required.

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Yan, HT., Lu, GD., Zhang, JX. et al. Comparison of Bronchial Artery Embolisation Versus Conservative Treatment for Bronchiectasis-Related Nonmassive Haemoptysis: A Single-Centre Retrospective Study. Cardiovasc Intervent Radiol 46, 369–376 (2023). https://doi.org/10.1007/s00270-023-03361-w

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  • DOI: https://doi.org/10.1007/s00270-023-03361-w

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