Skip to main content

Advertisement

Log in

Porcine Dermal Collagen (Permacol) for Facial Contour Augmentation: Preliminary Report

  • Published:
Aesthetic Plastic Surgery Aims and scope Submit manuscript

Abstract

Soft tissue loss or damage can occur for various reasons, including trauma, surgery, and disease. Reconstruction of normal contours can be achieved by using either alloplastic implants or autogenous tissues. Permacol, a dermal replacement material derived from fibrous acellular porcine dermal collagen, has been used for restoration of soft-tissue contours in the face. Eight patients were treated with porcine collagen in an attempt to achieve a smooth contour and a natural feel. Clinically visible soft tissue defects were successfully covered and aesthetic results were satisfying. Transient swelling that subsided within a week was noted in all patients. Meticulous and aseptic technique is mandatory for Permacol use. With this limited experience, Permacol was successfully used as a filler implant in reconstruction of post-traumatic soft-tissue defects, correcting post-parotidectomy hallowing and secondary nasal surgery to cover osseocartilaginous irregularities. However, there is a potential risk of inflammation and skin contractures in thin-skinned patients when implants are placed superficially.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
Figure 6
Figure 7

Similar content being viewed by others

References

  1. BM Achauer VM VanderKam B Celiköz DG Jacobson (1998) ArticleTitleAugmentation of facial soft-tissue defects with Alloderm dermal graft. Ann Plast Surg 41 503 Occurrence Handle1:STN:280:DyaK1M%2FktlKmtw%3D%3D Occurrence Handle9827953

    CAS  PubMed  Google Scholar 

  2. OA Adedeji CA Bailey JS Varma (2002) ArticleTitlePorcine dermal collagen graft in abdominal-wall reconstruction. Br J Plast Surg 55 85 Occurrence Handle10.1054/bjps.2001.3711 Occurrence Handle1:STN:280:DC%2BD38%2FlvVGqsg%3D%3D Occurrence Handle11783979

    Article  CAS  PubMed  Google Scholar 

  3. TS Alster TB West (2000) ArticleTitleHuman-derived and new synthetic injectable materials for soft-tissue augmentation: Current status and role in cosmetic surgery. Plast Reconstr Surg 105 2515

    Google Scholar 

  4. JW Barrington G Edwards (.) ArticleTitleMinimal access sling using PelvicolTM. Int J Urogynaecol J 11 IssueIDSuppl 1 V8 S122

    Google Scholar 

  5. HJCR Belcher R Zic (2001) ArticleTitleAdverse effect of porcine collagen interposition after trapezoidectomy. A comparative study. J Hand Surg (Br) 26B 159 Occurrence Handle10.1054/jhsb.2001.0554 Occurrence Handle12365051

    Article  PubMed  Google Scholar 

  6. E Billings Jr JW May Jr (1989) ArticleTitleHistorical review and present status of free fat graft autotransplantation in plastic and reconstructive surgery. Plast Reconstr Surg 83 368 Occurrence Handle2643129

    PubMed  Google Scholar 

  7. SA Castor WC To FA Papay (1999) ArticleTitleLip augmentation with Alloderm acellular dermal graft and fat autograft: A comparison with autologous fat injection. Aesth Plast Surg 23 218 Occurrence Handle10.1007/s002669900271

    Article  Google Scholar 

  8. DTW Chiu BW Edgerton (1990) Repair and grafting of dermis, fat, and fascia. JG McCarthy (Eds) Plastic Surgery. WB Saunders Philadelphia 508–526

    Google Scholar 

  9. WP Coleman N Lawrence RN Sherman RJ Reed KS Pinski (1993) ArticleTitleAutologous collagen. Lipocytic dermal augmentation: A histopathologic study. J Dermatol Surg Oncol 19 1032 Occurrence Handle8245302

    PubMed  Google Scholar 

  10. OO Erol (2000) ArticleTitleFacial autologous soft-tissue contouring by adjunction of tissue cocktail injection (Micrograft and minigraft mixture of dermis, fascia, and fat). Plast Reconstr Surg 106 1375

    Google Scholar 

  11. RW Griffiths PG Shakespeare (1982) ArticleTitleHuman dermal collagen allografts: A three year histopathological study. Br J Plast Surg 35 519 Occurrence Handle1:STN:280:BiyD2cbntFE%3D Occurrence Handle7139181

    CAS  PubMed  Google Scholar 

  12. C Harper (2001) ArticleTitlePermacol™: clinical experience with a new biomaterial. Hosp Med 62 90 Occurrence Handle1:STN:280:DC%2BD3M7otleluw%3D%3D Occurrence Handle11236624

    CAS  PubMed  Google Scholar 

  13. RTJ Holl-Allen (1984) ArticleTitlePorcine dermal collagen implants in man. J R Coll Surg Edinb 29 151 Occurrence Handle1:STN:280:BiuB28jlsl0%3D Occurrence Handle6747918

    CAS  PubMed  Google Scholar 

  14. IT Jackson R Yavuzer (2000) ArticleTitleHydroxyapatite cement: An alternative for craniofacial skeletal contour refinements. Br J Plast Surg 53 24 Occurrence Handle1:STN:280:DC%2BD3c3gvFSgtw%3D%3D Occurrence Handle10657445

    CAS  PubMed  Google Scholar 

  15. TC Kononas LP Bucky C Hurley JW May Jr (1993) ArticleTitleThe fate of suctioned and surgically removed fat after implantation for soft-tissue augmentation: A volumetric and histologic study in the rabbit. Plast Reconstr Surg 91 763

    Google Scholar 

  16. JW Little (2002) ArticleTitleApplications of the classic dermal fat graft in primary and secondary facial rejuvenation. Plast Reconstr Surg 109 788

    Google Scholar 

  17. AM Nacul AP Nacul AG de Born (1998) ArticleTitleBioplastique as a complement in conventional plastic surgery. Aesth Plast Surg 22 444 Occurrence Handle10.1007/s002669900232 Occurrence Handle1:STN:280:DyaK1M%2FmvV2isQ%3D%3D

    Article  CAS  Google Scholar 

  18. FV Nicolle BA Matti T Scamp (1992) ArticleTitleDermal and fascial autografts in facial aesthetic surgery. Aesth Plast Surg 16 219 Occurrence Handle1:STN:280:By2A38jpt1M%3D

    CAS  Google Scholar 

  19. BA Ruparelia K GunasheelaSundar (2000) ArticleTitleAnterior and posterior vaginal collapse repairs with porcine skin collagen (Permacol™) implant. Int Urogynaecol J 11 IssueIDSuppl FDP33 S45

    Google Scholar 

  20. K Sevin I Askar A Saray E Yormuk (2000) ArticleTitleExposure of high-density porous polyethylene (Medpor) used for contour restoration and treatment. Br J Oral Maxillofac Surg 38 44 Occurrence Handle1:STN:280:DC%2BD3c3kvVyltA%3D%3D Occurrence Handle10783447

    CAS  PubMed  Google Scholar 

  21. AP Sclafani T Romo III (2000) ArticleTitleBiology and chemistry of facial implants. Facial Plast Surg 16 3 Occurrence Handle1:STN:280:DC%2BD38%2FnsFCquw%3D%3D Occurrence Handle11802344

    CAS  PubMed  Google Scholar 

  22. AP Sclafani T Romo III A Parker SA McCormick R Cocker A Jacono (2002) ArticleTitleHomologous collagen dispersion (Dermalogen) as a dermal filler: Persistence and histology compared with bovine collagen. Ann Plast Surg 49 181 Occurrence Handle10.1097/00000637-200208000-00011 Occurrence Handle12187346

    Article  PubMed  Google Scholar 

  23. BB Ward SE Feinberg CD Friedman (2002) ArticleTitleTissue matrices for soft tissue and mucosal augmentation and replacement. Facial Plast Surg 18 3 Occurrence Handle10.1055/s-2002-19822 Occurrence Handle11823928

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Aydin Saray.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Saray, A. Porcine Dermal Collagen (Permacol) for Facial Contour Augmentation: Preliminary Report . Aesth. Plast. Surg. 27, 368–375 (2003). https://doi.org/10.1007/s00266-003-3012-3

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00266-003-3012-3

Keywords

Navigation