Skip to main content

Advertisement

SpringerLink
Log in

Hip score and disease activity correlation in patients with rheumatoid arthritis after total hip arthroplasty

  • Original Paper
  • Published:
International Orthopaedics Aims and scope Submit manuscript

    We’re sorry, something doesn't seem to be working properly.

    Please try refreshing the page. If that doesn't work, please contact support so we can address the problem.

Abstract

Purpose

The disease activity score including 28 joints (DAS28), the simplified disease activity index and the clinical disease activity index (CDAI) were developed in order to provide a quantifiable measure of rheumatoid arthritis (RA) activity. Although inflamed hip joints greatly impact activities of daily living (ADL) and walking ability, the hip joint was not included in the DAS28, SDAI or CDAI assessments. Although excellent clinical results have been reported for total hip arthroplasty (THA) in RA patients, correlations between disease activity and hip function in RA patients after THA remain unknown.

Methods

We analysed the effect of RA disease activity on a hip function score in an observational cohort of RA patients after THA. Twenty-five registered RA patients who had undergone THA (33 joints) were included. Hip function was recorded and RA disease activity was measured on the same day. The mean age of the patients was 65.17 years. They were followed up for a mean of 5.24 years after surgery. The mean duration of disease following RA diagnosis for this patient group was 19.47 years. The Japanese Orthopaedic Association (JOA) hip score was used as a clinical outcome measure for hip dysfunction. RA disease activity and health-related quality of life were measured using the DAS28, SDAI, CDAI and the modified health assessment questionnaire (MHAQ).

Results

The mean JOA score for hip function was 80.48 at the final follow-up. The mean DAS28-ESR, DAS28-CRP, SDAI, CDAI and MHAQ measuring RA disease activity levels were 3.38, 2.65, 9.59, 8.63 and 0.44, respectively, at the final follow-up. There was a significant negative correlation between the JOA hip score and all disease activity assessments observed after THA (DAS-ESR [P = 0.0067], DAS-CRP [P = 0.0008]), SDAI [P = 0.0034], CDAI [P = 0.0003]) and MHAQ [P = 0.0002]).

Conclusion

We found significant negative correlations between JOA hip scores and all disease activity assessments in RA patients treated with THA.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Similar content being viewed by others

References

  1. Van Zeben D, Hazes JM, Zwinderman AH, Vandenbroucke JP, Breedveld FC (1993) Factors predicting outcome of rheumatoid arthritis: results of a followup study. J Rheumatol 20:1288–1296

    PubMed  Google Scholar 

  2. Anderson RJ (1996) The orthopedic management of rheumatoid arthritis. Arthritis Care Res 9:223–228

    Article  PubMed  CAS  Google Scholar 

  3. Prevoo ML, van’t Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL (1995) Modified disease activity scores that include twenty–eight–joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum 48:3844–3848

    Google Scholar 

  4. Smolen JS, Breedveld FC, Schiff MH, Kalden JR, Emery P, Eberl G, van Riel PL, Tugwell P (2003) A simplified disease activity index for rheumatoid arthritis for use in clinical practice. Rheumatology (Oxford) 42:244–257

    Article  CAS  Google Scholar 

  5. Aletaha D, Nell VP, Stamm T, Uffmann M, Pflugbeil S, Machold K, Smolen JS (2005) Acute phase reactants add little to disease activity indices for rheumatoid arthritis- validation of a clinical activity score. Arthritis Res Ther 7:796–806

    Article  Google Scholar 

  6. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, Healey LA, Kaplan SR, Liang MH, Luthra HS et al (1988) The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 31:315–324

    Article  PubMed  CAS  Google Scholar 

  7. Kuribayashi M, Takahashi KA, Fujioka M, Ueshima K, Inoue S, Kubo T (2010) Reliability and validity of the Japanese Orthopaedic Association hip score. J Orthop Sci 15:452–458

    Article  PubMed  Google Scholar 

  8. Pincus T, Summey JA, Soraci SA, Wallston KA, Hummon NP (1983) Assessment of patient satisfaction in activities of daily living using a modified Stanford health assessment questionnaire. Arthritis Rheum 26:1346–1353

    Article  PubMed  CAS  Google Scholar 

  9. Wolfe F, Zwillich SH (1998) The long-term outcomes of rheumatoid arthritis: a 23-year prospective, longitudinal study of total joint replacement and its predictors in 1,600 patients with rheumatoid arthritis. Arthritis Rheum 41:1072–1082

    Article  PubMed  CAS  Google Scholar 

  10. Lee YH, Woo JH, Rho YH, Choi SJ, Ji JD, Song GG (2008) Meta-analysis of the combination of TNF inhibitors plus MTX compared to MTX monotherapy, and the adjusted indirect comparison of TNF inhibitors in patients suffering from active rheumatoid arthritis. Rheumatol Int 28:553–559

    Article  PubMed  CAS  Google Scholar 

  11. Koike T, Harigai M, Inokuma S, Ishiguro N, Ryu J, Takeuchi T, Tanaka Y, Yamanaka H, Fujii K, Yoshinaga T, Freundlich B, Suzukawa M (2012) Safety and effectiveness responses to etanercept for rheumatoid arthritis in Japan: a sub-analysis of a post-marketing surveillance study focusing on the duration of rheumatoid arthritis. Rheumatol Int 32:1511–1519

    Article  PubMed  CAS  Google Scholar 

  12. Wiens A, Correr CJ, Venson R, Otuki MF, Pontarolo R (2010) A systematic review and meta-analysis of the efficacy and safety of adalimumab for treating rheumatoid arthritis. Rheumatol Int 30:1063–1070

    Article  PubMed  CAS  Google Scholar 

  13. Takeuchi T, Miyasaka N, Inoue K, Abe T, Koike T, RISING study (2009) Impact of trough serum level on radiographic and clinical response to infliximab plus methotrexate in patients with rheumatoid arthritis: results from the RISING study. Mod Rheumatol 19:478–487

    Article  PubMed  CAS  Google Scholar 

  14. van der Heijde D, Klareskog L, Landewé R, Bruyn GA, Cantagrel A, Durez P, Herrero-Beaumont G, Molad Y, Codreanu C, Valentini G, Zahora R, Pedersen R, MacPeek D, Wajdula J, Fatenejad S (2007) Disease remission and sustained halting of radiographic progression with combination etanercept and methotrexate in patients with rheumatoid arthritis. Arthritis Rheum 56:3928–3939

    Article  PubMed  Google Scholar 

  15. Louie GH, Ward MM (2010) Changes in the rates of joint surgery among patients with rheumatoid arthritis in California, 1983–2007. Ann Rheum Dis 69:868–871

    Article  PubMed  Google Scholar 

  16. Momohara S, Inoue E, Ikari K, Kawamura K, Tsukahara S, Iwamoto T, Hara M, Taniguchi A, Yamanaka H (2010) Decrease in orthopaedic operations, including total joint replacements, in patients with rheumatoid arthritis between 2001 and 2007: data from Japanese outpatients in a single institute-based large observational cohort (IORRA). Ann Rheum Dis 69:312–313

    Article  PubMed  CAS  Google Scholar 

  17. Rud-Sørensen C, Pedersen AB, Johnsen SP, Riis AH, Overgaard S (2010) Survival of primary total hip arthroplasty in rheumatoid arthritis patients. Acta Orthop 81:60–65

    Article  PubMed  Google Scholar 

  18. Zwartele R, Peters A, Brouwers J, Olsthoorn P, Brand R, Doets C (2008) Long-term results of cementless primary total hip arthroplasty with a threaded cup and a tapered, rectangular titanium stem in rheumatoid arthritis and osteoarthritis. Int Orthop 32:581–587

    Article  PubMed  Google Scholar 

  19. Momohara S, Inoue E, Ikari K, Yano K, Tokita A, Suzuki T, Sakuma Y, Hiroshima R, Kawakami K, Masuda I, Iwamoto T, Taniguchi A, Yamanaka H (2011) Efficacy of total joint arthroplasty in patients with established rheumatoid arthritis: improved longitudinal effects on disease activity but not on health-related quality of life. Mod Rheumatol 21:476–481

    Article  PubMed  Google Scholar 

Download references

Acknowledgments

No benefits or funds were received in support of the study.

Conflict of interest

The authors have declared no conflicts of interest.

Author information

Authors and Affiliations

  1. Department of Orthopaedic Surgery, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan

    Hiroki Wakabayashi, Masahiro Hasegawa, Kakunoshin Yoshida & Akihiro Sudo

  2. Institute of Medical Science, Tokyo Medical University, Tokyo, Japan

    Kusuki Nishioka

Authors
  1. Hiroki Wakabayashi
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Masahiro Hasegawa
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Kakunoshin Yoshida
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Kusuki Nishioka
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Akihiro Sudo
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Hiroki Wakabayashi.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Wakabayashi, H., Hasegawa, M., Yoshida, K. et al. Hip score and disease activity correlation in patients with rheumatoid arthritis after total hip arthroplasty. International Orthopaedics (SICOT) 37, 1245–1250 (2013). https://doi.org/10.1007/s00264-013-1900-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00264-013-1900-y

Keywords

Search

Navigation