Abstract
We designed to investigate the feasibility of multi-detector row computerized tomography (CT) as a “one-stop” examination for the simultaneous preoperative evaluation of the morphology and function of living renal donors. 21 living renal donors were examined by 64-slice spiral CT with a three-phase enhancement CT scan and two inserted dynamic scans. The maximum intensity projection (MIP), multi-planar reformation (MPR), and volume reconstruction (VR) procedures were performed to compare the renal parenchyma, renal vessels, and collecting system with operational findings. The known Patlak equation was used to calculate the glomerular filtration rate (GFR); exact GFR information was acquired by single photon emission computed tomography (SPECT). Our results as following, there were 3 cases of artery variation and 3 cases of vein variation. CT findings all corresponded with the operation, and the sensitivity, positive predictive value, specialty, and negative predictive value of CT were all 100%. The r of the GFR values estimated from CT is 0.894 (left) (P < 0.001) and 0.881 (right) (P < 0.001). In conclusions, our findings demonstrate that 64-slice spiral CT may offer a “one-stop” examination to replace SPECT in the preoperative evaluation of living renal donors to simultaneously provide information regarding both anatomy and the GFR of living renal donors.
Similar content being viewed by others
References
Kim JK, Park SY, Kim HJ, et al. (2003) Living donor kidneys: usefulness of multi-detector row CT for comprehensive evaluation. Radiology 229:869–876
Janoff DM, Davol P, Hazzard J, et al. (2004) Computerized tomography with 3-dimensional reconstruction for the evaluation of renal size and arterial anatomy in the living kidney donor. J Urol 171:27–30
Lewis GR, Mulcahy K, Brook NR, Veitch PS, Nicholson ML (2004) A prospective study of the predictive power of spiral computed tomographic angiography for defining renal vascular anatomy before live-donor nephrectomy. BJU Int 94:1077–1081
O’Reilly PH, Brooman PJ, Martin PJ, et al. (1986) Accuracy and reproducibility of a new contrast clearance method for the determination of glomerular filtration rate. Br Med J (Clin Res Ed) 293:234–236
Patlak CS, Blasberg RG, Fenstermacher JD (1983) Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. J Cereb Blood Flow Metab 3:1–7
Hackstein N, Wiegand C, Rau WS, Langheinrich AC (2004) Glomerular filtration rate measured by using triphasic helical CT with a two-point Patlak plot technique. Radiology 230:221–226
Dawson P, Peters M (1993) Dynamic contrast bolus computed tomography for the assessment of renal function. Invest Radiol 28:1039–1042
Tsushima Y, Blomley MJ, Kusano S, Endo K (1999) Use of contrast-enhanced computed tomography to measure clearance per unit renal volume: a novel measurement of renal function and fractional vascular volume. Am J Kidney Dis 33:754–760
Competing interests.
The authors declare that they have no competing interests.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Su, C., Yan, C., Guo, Y. et al. Multi-detector row CT as a “one-stop” examination in the preoperative evaluation of the morphology and function of living renal donors: preliminary study. Abdom Imaging 36, 86–90 (2011). https://doi.org/10.1007/s00261-009-9595-7
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00261-009-9595-7