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Pre- and post-operative work-up in patients affected by early cervical cancer and eligible for fertility-sparing treatment: role of MRI with saline hydrocolpos

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Abstract

Nowadays young women affected by early invasive uterine cervical cancer (stage IA2-IB1) may be offered a fertility-sparing treatment: the radical trachelectomy with pelvic lymph node dissection. This procedure consists in surgical removal of cervix uteri, proximal parametrial tissue, and vaginal cuff. The morphology and the functions of corpus uteri are preserved. Women candidates for trachelectomy must be closely selected. Gynecologist oncologist needs an imaging modality that can accurately value the tumoral diameter and which can demonstrate proximal extension of tumor to ensure surgical clear resection margins (especially the cranial one). Magnetic resonance imaging (MRI) is a very useful examination in pre-operative study of women affected by early cervical cancer. The aim of this study is to evaluate the role of MRI with hydrocolpos about pre- and post-operative work-up in women eligible for fertility-sparing treatment.

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References

  1. International Agency for Research on Cancer (2005) Cervical cancer screening. In: IARC Handbooks of Cancer Prevention, Volume 10. Lyon: IARC Press, pp 1–299

  2. Ramirez PT, Levenback C. Radical trachelectomy: is it here to stay? Gynecol Oncol 2004; 94: 611-13.

    Article  PubMed  Google Scholar 

  3. Smith HO, Tiffany MF, Qualls CR, Key CR. The rising incidence of adenocarcinoma relative to squamous cell carcinoma of the uterine cervix in the United States – A 24-year population-based study. Gynecol Oncol 2000; 78: 97-105.

    Article  CAS  PubMed  Google Scholar 

  4. Marchiole P, Benchaib M, Buenerd A et al. Oncological safety of laparoscopic-assisted vaginal radical trachelectomy (LARVT or Dargent’s operation): a comparative study with laparoscopic-assisted radical hysterectomy (LARVH). Gynecol Oncol 2007; 106(1): 132-41.

    Article  PubMed  Google Scholar 

  5. Beiner ME, Covens A. Surgery insight: radical vaginal trachelectomy as a method of fertility preservation for cervical cancer. Nat Clin Pract Oncol 2007; 4: 353-61.

    Article  PubMed  Google Scholar 

  6. Burnett AF. Radical trachelectomy with laparoscopic lymphadenectomy: review of oncologic and obstetrical outcomes. Curr Opin Obstet Gynecol 2006; 18: 8-13.

    Article  PubMed  Google Scholar 

  7. Plante M, Renaud MC, François H, Roy M. Vaginal radical trachelectomy: an oncologically safe fertility-preserving surgery An update series of 72 cases and review of the literature. Gynecol Oncol 2004; 94: 614-23.

    Article  PubMed  Google Scholar 

  8. Plante M. Vaginal radical trachelectomy: An update. Gynecol Oncol 2008; 111: 105-10.

    Article  Google Scholar 

  9. Plante M, Lau S, Brydon L et al. Neoadjuvant chemotherapy followed by vaginal radical trachelectomy in bulky stage IB1 cervical cancer: Case report. Gynecol Oncol 2006; 101(2): 367-70.

    Article  PubMed  Google Scholar 

  10. Rob L, Pluta M, Strnad P et al. A less radical treatment option to the fertility sparing radical trachelectomy in patients with stage I cervical cancer. Gynecol Oncol 2008; 111: 116-20.

    Article  Google Scholar 

  11. Hertel H, Kohler C, Grund D et al. Radical vaginal trachelectomy (RVT) combined with laparoscopic pelvic lymphadenectomy: prospective multicenter study of 100 patients with early cervical cancer. Gynecol Oncol 2006; 103: 506-11.

    Article  PubMed  Google Scholar 

  12. Covens A. Preserving fertility in early cervical Ca with radical trachelectomy. Contemp Ob/Gyn 2003;2:46-66.

    Google Scholar 

  13. Shepherd JH, Spencer C, Herold J et al. Radical vaginal trachelectomy as a fertility sparing procedure in women with early-stage cervical cancer – cumulative pregnancy rate in a series of 123 women. BJOG 2006; 113: 719-24.

    Article  CAS  PubMed  Google Scholar 

  14. Sagili H. Regarding radical vaginal trachelectomy as a fertility sparing procedure in women with early-stage cervical cancer – cumulative pregnancy rate in a series of 123 women. BJOG 2007; 114: 115-6.

    CAS  PubMed  Google Scholar 

  15. Burnett AF, Roman LD, O’Meara AT et al. Radical vaginal trachelectomy and pelvic lymphadenectomy for preservation of fertility in early cervical cancer. Gynecol Oncol 2003; 88: 419-23.

    Article  PubMed  Google Scholar 

  16. Schlaerth JB, Spirtos NM, Schlaerth AC. Radical trachelectomy and pelvic lymphadenectomy with uterine preservation in the treatment of cervical cancer. Am J Obstet Gynecol 2003; 188: 29-34.

    Article  PubMed  Google Scholar 

  17. Sahdev A, Jones J, Shepherd JH, Reznek RH. MR imaging appearances of the female pelvis after trachelectomy. Radiographics 2005; 25(1): 41-52.

    Article  PubMed  Google Scholar 

  18. Peppercorn PD, Jeyarajah AR, Woolas R et al. Role of MR imaging in the selection of patients with early cervical carcinoma for fertility preserving surgery: initial experience. Radiology 1999; 212: 395-399.

    CAS  PubMed  Google Scholar 

  19. Reznek RH and Sahdev A. MR imaging in cervical cancer: seeing is believing. The British Journal of Radiology 2005; 78: 73-85.

    Article  Google Scholar 

  20. Ozsarlak O, Tjalma W, Schepens E et al. The correlation of preoperative CT, MR imaging and clinical staging (FIGO) with histopathology findings in primary cervical carcinoma. Eur Radiol 2003; 13(10): 2338-45.

    Article  CAS  PubMed  Google Scholar 

  21. Kobayashi Y, Akiyama F, Hasumi K. A case of successful pregnancy after treatment of invasive cervical cancer with systemic chemotherapy and conisation. Gynecol Oncol 2006; 100: 213-215.

    Article  PubMed  Google Scholar 

  22. Maneo A, Chiari S, Bonazzi C, Mangioni C. Neoadjuvant chemotherapy and conservative surgery for stage IB1 cervical cancer. Gynecol Oncol 2008; 111(3): 438-43.

    Article  PubMed  Google Scholar 

  23. Landoni F, Parma G, Peiretti M et al. Chemo-conisation in early cervical cancer. Gynecol Oncol 2007; 107: 125-6.

    Article  Google Scholar 

  24. Yang WT, Lam WWM, Yu MY et al. Comparison of dynamic helical CT and dynamic MR imaging in the evaluation of pelvic lymph nodes in cervical carcinoma. AJR Am J Roentgenol 2000; 175(3): 759-66.

    CAS  PubMed  Google Scholar 

  25. Dornhofer N and Hockel M. New developments in the surgical therapy of cervical carcinoma. Ann NY Acad Sci 2008; 1138: 233-252.

    Article  PubMed  Google Scholar 

  26. Bats A, Mathevet P, Querleu D et al. Assessment of sentinel biopsy value for early cervical cancer: Results of a multicenter study [Abstract]. Gynecol Oncol 2008; 108: 32-155.

    Article  Google Scholar 

  27. Strnad P, Robova H, Skapa P et al. A prospective study of sentinel lymph node status and parametrial involvement in patients with small tumour volume cervical cancer. Gynecol Oncol 2008; 109: 280-284.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Ginecology and Obstetrics, San Martino Hospital, University of Genova, Genova, Italy

    Pierangelo Marchiolè, Paolo Sala, Melita Moioli & Sergio Costantini

  2. Department of Radiology, San Martino Hospital, University of Genova, Genova, Italy

    Giuseppe Cittadini & Enrico Capaccio

  3. Department of Ginecology and Obstetrics, Hospital Femme-Mère-Enfant, Lyon-Bron, France

    Patrice Mathevet

Authors
  1. Pierangelo Marchiolè
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  2. Giuseppe Cittadini
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  3. Paolo Sala
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  4. Melita Moioli
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  5. Patrice Mathevet
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  6. Enrico Capaccio
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  7. Sergio Costantini
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Correspondence to Pierangelo Marchiolè.

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Marchiolè, P., Cittadini, G., Sala, P. et al. Pre- and post-operative work-up in patients affected by early cervical cancer and eligible for fertility-sparing treatment: role of MRI with saline hydrocolpos. Abdom Imaging 35, 271–279 (2010). https://doi.org/10.1007/s00261-009-9511-1

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  • DOI: https://doi.org/10.1007/s00261-009-9511-1

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