Skip to main content

Advertisement

SpringerLink
Log in

Biliary cystic intraductal papillary mucinous tumor and cystadenoma/cystadenocarcinoma: differentiation by CT

  • Published:
Abdominal Imaging Aims and scope Submit manuscript

Abstract

Purpose

To identify differential findings of biliary cystic intraductal papillary mucinous tumor (IPMT) and biliary cystadenoma/cystadenocarcinoma on CT images.

Materials and methods

Records of 7 patients with biliary cystic IPMT and 17 patients with biliary cystadenoma/cystadenocarcinoma were accessed. A pathologist reviewed gross morphologic and microscopic findings and confirmed the diagnosis. Two radiologists who were blind to the pathologic diagnosis reviewed CT images regarding size of cystic mass, mural nodule, septa, calcification, dilatation of the proximal, and distal bile ducts to the tumor, and the results were analyzed using multivariate analysis.

Results

Mural nodule and dilatation of the bile ducts distal to the cystic tumor were more commonly seen in patients with cystic IPMT than in patients with biliary cystadenoma/cystadenocarcinoma and these are statistically significant, the P values being 0.029 and 0.016, respectively. Size of the cystic tumor, presence of septa, calcification, and dilatation of the bile duct proximal to the cystic tumor were not statistically different.

Conclusion

Biliary cystic IPMT could be differentiated from biliary cystadenoma/cystadenocarcinoma on CT images based on the presence of mural nodules and dilatation of the bile ducts distal to the cystic tumor.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1.
Fig. 2.
Fig. 3.
Fig. 4.
Fig. 5.

Similar content being viewed by others

References

  1. Murphy BJ, Casillas J, Ros PR, et al. (1989) The CT appearance of cystic masses of the liver. RadioGraphics 9:307–322

    PubMed  CAS  Google Scholar 

  2. Buetow PC, Midkiff RB (1997) MR imaging of the liver. Primary malignant neoplasm in the adult. Magn Reson Imaging Clin N Am 5:289–318

    PubMed  CAS  Google Scholar 

  3. Korobkin M, Stephens DH, Lee JK, et al. (1989) Biliary cystadenoma and cystadenocarcinoma: CT and sonographic findings. AJR 153:507–511

    PubMed  CAS  Google Scholar 

  4. Buetow PC, Buck JL, Pantongrag-Brown L, et al. (1995) Biliary cystadenoma and cystadenocarcinoma: clinical-imaging-pathologic correlations with emphasis on the importance of ovarian stroma. Radiology 196:805–810

    PubMed  CAS  Google Scholar 

  5. Choi BI, Lim JH, Han MC, et al. (1989) Biliary cystadenoma and cystadenocarcinoma: CT and sonographic findings. Radiology 171:57–61

    PubMed  CAS  Google Scholar 

  6. Mortele KJ, Ros PR (2001) Cystic focal liver lesions in the adult: differential CT and MR imaging features. RadioGraphics 21:895–910

    PubMed  CAS  Google Scholar 

  7. Forrest ME, Cho KJ, Shields JJ, et al. (1980) Biliary cystadenomas: sonographic-angiographic-pathologic correlations. AJR 135:723–727

    PubMed  CAS  Google Scholar 

  8. Frick MP, Feinberg SB (1982) Biliary cystadenoma. AJR 139:393–395

    PubMed  CAS  Google Scholar 

  9. Nakanuma Y, Sasaki M, Ishikawa A, Tsui W, Chen TC, Huang SF (2002) Biliary papillary neoplasm of the liver. Histol Histopathol 27:851–861

    Google Scholar 

  10. Lim JH, Yoon KH, Kim SH, et al. (2004) Intraductal papillary mucinous tumor of the bile duct. RadioGraphics 24:53–66

    Article  PubMed  Google Scholar 

  11. Lee JW, Han JK, Kim TK, et al. (2000) CT features of intraductal intrahepatic cholangiocarcinoma. AJR 175:721–725

    PubMed  CAS  Google Scholar 

  12. Yoon KH, Han HK, Kim CG, et al. (2000) Malignant papillary neoplasms of the intrahepatic bile ducts: CT and histopathologic features. AJR 175:1135–1139

    PubMed  CAS  Google Scholar 

  13. Han JK, Lee JM (2004) Intrahepatic intraductal cholangiocarcinoma. Abdom Imaging 29:558–564

    Article  PubMed  CAS  Google Scholar 

  14. Terada T, Taniguchi M (2004) Intraductal oncocytic papillary neoplasm of the liver. Pathol Int 54:116–123

    Article  PubMed  Google Scholar 

  15. Aoki S, Okayama Y, Kitajima Y, et al. (2005) Intrahepatic biliary papilloma morphologically similar to biliary cystadenoma. J Gastroenterol Hepatol 20:321–324

    Article  PubMed  Google Scholar 

  16. Kosumahl M, Pauser U, Peters K, et al. (2004) Cystic neoplasms of the pancreas and tumor-like lesions with cystic features: a review of 418 cases and a classification proposal. Virchow Arch 445:168–178

    Google Scholar 

  17. Fukushima N, Mukai K (2000) Differential diagnosis between intraductal papillary-mucinous tumors and mucinous cystic tumors of the pancreas. Int J Surg Pathol 8:271–278

    Article  PubMed  Google Scholar 

  18. Procacci C, Graziani R, Bicego E, et al. (1996) Intraductal mucin-producing tumors of the pancreas: imaging findings. Radiology 198:249–257

    PubMed  CAS  Google Scholar 

  19. Kim HJ, Kim MH, Lee SK, et al. (2000) Mucin-hypersecreting bile duct tumor characterized by a striking homology with an intraductal papillary mucinous tumor (IPMT) of the pancreas. Endoscopy 32:389–393

    Article  PubMed  CAS  Google Scholar 

  20. Hubens G, Delvaux G, Willems G, et al. (1991) Papillomatosis of the intra- and extrahepatic bile ducts with involvement of the pancreatic duct. Hepatogastroenterology 38:413–418

    PubMed  CAS  Google Scholar 

  21. Joo YH, Kim MH, Lee SK, et al. (2000) A case of mucin-hypersecreting intrahepatic bile duct tumor associated with pancreatic intraductal papillary mucinous tumor. Gastrointest Endosc 52:409–412

    Article  PubMed  CAS  Google Scholar 

Download references

Acknowledgements

Authors wish to thank Dr. John Roberts for his editorial assistance and Young Joo Moon for her assistance in manuscript preparation.

Author information

Authors and Affiliations

  1. Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, Seoul, 135-710, South Korea

    Jae Hoon Lim, Hyunchul Rhim & Young Sun Kim

  2. Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, Seoul, 135-710, South Korea

    Kee-Taek Jang

  3. Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, Seoul, 135-710, South Korea

    Kyu Taek Lee

  4. Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, Seoul, 135-710, South Korea

    Sung Ho Choi

Authors
  1. Jae Hoon Lim
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Kee-Taek Jang
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Hyunchul Rhim
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Young Sun Kim
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Kyu Taek Lee
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Sung Ho Choi
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jae Hoon Lim.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lim, J.H., Jang, KT., Rhim, H. et al. Biliary cystic intraductal papillary mucinous tumor and cystadenoma/cystadenocarcinoma: differentiation by CT. Abdom Imaging 32, 644–651 (2007). https://doi.org/10.1007/s00261-006-9161-5

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00261-006-9161-5

Keywords

Search

Navigation