One of the most important goals that a scientist can dream of achieving is to publish a book with his/her name in the title. This is what happens in the Osborn’s Brain: Imaging, Pathology and Anatomy, now at its third edition, arriving 30 years after the pivotal book Diagnostic Neuroradiology, also known as the Red Book, one of the all-time bestselling neuroradiology texts.

If the aspiration to have a book personalized with your own surname is a dream for the vast majority of scientific authors, this is instead a reality for Anne G. Osborn, who deserves the honour and justification of her name in the title, thanks to its impressive curriculum, which even today continues to develop towards the future.

Anne G. Osborn, one of the most important and influential international personalities in neuroradiology, is currently a University Distinguished Professor and Professor of Radiology and Imaging Sciences at the University of Utah, in Salt Lake City. This edition, which saw the collaboration of many contributors, was edited together with Luke L. Linscott, Paediatric Neuroradiologist at the Primary Children’s Hospital, Salt Lake City, and Karen L. Salzman, Neuroradiologist, Professor of Radiology and Imaging Sciences at the University of Utah.

This edition arrives almost 5 years after the second and has substantial changes compared to the previous one, due to the entry into clinical practice, in late 2021, of the fifth edition of the WHO Classification of Tumours: Central Nervous System Tumours. This document has partially revolutionized the management and evaluation criteria of the brain neoplasms, actually mainly based on molecular pathology, determining a substantial revision and extension of chapters related to oncological issues. At the same time, the sections concerning non-oncology areas have been however updated, also including new images and information.

More precisely, the 1400-page book with approximately 4000 images and diagrams of high technical and educational quality, which represent all the most important pathological conditions, including the less frequent ones, and also containing an enhanced digital version, is organized into six sections which concern respectively: (1) trauma; (2) non-traumatic haemorrhage and vascular lesions; (3) infection, inflammation and demyelinating diseases; (4) neoplasms, cysts and tumour-like lesions; (5) toxic, metabolic, degenerative and CSF disorders; (6) congenital malformations and genetic tumour syndromes.

The great personality and experience of Dr. Osborn created the conditions that the text, substantially based on the previous editions, appears homogeneous in its structure and composition with chapters that are all in-depth and updated, written in a clear manner, yet easily understandable even by non-super-specialists. In fact, it is interesting to note how, although there are many authors, the overall vision is similar, defined by the teaching experience and multidisciplinary vision of Osborn, who considers the active correlation between neuropathology, neurosurgery and clinical neurosciences important within a neuroradiological information that must not only make a diagnosis, but also identify classification criteria and information related to prognosis and therapy.

The main target of the book is clearly neuroradiologists both in training and already active in clinical practice. The relevance and authoritativeness of the text also make it a book of interest to all those, radiologists, neurologists, neurosurgeons, oncologists, pathologists and all professionals interested in the brain, either as seasoned practitioner or resident or fellow.