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Microbial metabolism and biotechnological production of d-allose

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Abstract

d-Allose has attracted a great deal of attention in recent years due to its many pharmaceutical activities, which include anti-cancer, anti-tumor, anti-inflammatory, anti-oxidative, anti-hypertensive, cryoprotective, and immunosuppressant activities. d-Allose has been produced from d-psicose using d-allose-producing enzymes, including l-rhamnose isomerase, ribose-5-phosphate isomerase, and galactose-6-phosphate isomerase. In this article, the properties, applications, and metabolism of d-allose are described, and the biochemical properties of d-allose-producing enzymes and their d-allose production are reviewed and compared. Moreover, several methods for effective d-allose production are suggested herein.

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Acknowledgment

This study was supported by the Korea Science and Engineering Foundation (KOSEF) through the National Research Laboratory Program funded by the Ministry of Education, Science and Technology (R0A-2007-000-20015-0).

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  1. Department of Bioscience and Biotechnology, Konkuk University, 1 Hwayang-Dong Gwangjin-Gu, Seoul, 143-701, South Korea

    Yu-Ri Lim & Deok-Kun Oh

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  1. Yu-Ri Lim
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Correspondence to Deok-Kun Oh.

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Lim, YR., Oh, DK. Microbial metabolism and biotechnological production of d-allose. Appl Microbiol Biotechnol 91, 229–235 (2011). https://doi.org/10.1007/s00253-011-3370-8

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