Abstract
A new method for repackaging optical metamaterials formed from quartz spheres (fibers) of various diameters is proposed for ultraviolet C disinfection of infected liquids by pathogens (viruses and bacteria). The main idea of the new equipment is connected with the rotation of a contaminated fluid by screw channels within a metamaterial matrix prepared from UVC fibers/spherical optics, to improve the decontamination efficiency. In demonstration of the viability of this approach, dynamic and static inactivation of Baker's yeast via Ultraviolet C radiation regimes are used in this paper to show the efficacy of decontamination within the screw channels.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Data availability
The authors declare that the data in the paper are available.
References
Boraas ME, Seale DB, Boxhorn JE (1998) Phagotrophy by a flagellate selects for colonial prey: a possible origin of multicellularity. Evol Ecol 12:153–164. https://doi.org/10.1023/A:1006527528063
Born M, Oppenheimer R (1927) Zur Quantentheorie der Molekeln. Ann Phys 389:457–484
Buonanno M, Welch D, Shuryak I, Brenner DJ (2020) Far-UVC light (222 nm) efficiently and safely inactivates airborne human coronaviruses. Sci Rep 10:10285
Cadnum JL, Shaikh AA, Piedrahita CT, Jencson AL, Larkin EL, Ghannoum MA, Donskey CJ (2018) Relative resistance of the emerging fungal pathogen Candida auris and other Candida species to killing by ultraviolet light. Infect Control Hosp Epidemiol 39(1):94–96. https://doi.org/10.1017/ice.2017.239. (Epub 2017 Nov 21 PMID: 29157326)
Chin AWH, Chu JTS, Perera MRA, Hui KPY, Yen HL, Chan MCW, Peiris M, Poon LLM (2020) Stability of SARS-CoV-2 in different environmental conditions. Lancet Microbe 1(1):e10. https://doi.org/10.1016/S2666-5247(20)30003-3. (Epub 2020 Apr 2. PMID: 32835322; PMCID: PMC7214863)
Chirizzi D, Conte M, Feltracco M, Dinoi A, Gregoris E, Barbaro E, La Bella G, Ciccarese G, La Salandra G, Gambaro A, Contini D (2021) SARS-CoV-2 concentrations and virus-laden aerosol size distributions in outdoor air in north and south of Italy. Environ Int 146:106255. https://doi.org/10.1016/j.envint.2020.106255. (Epub 2020 Nov 12. PMID: 33221596; PMCID: PMC7659514)
Comber LO, Murchu E, Drummond L, Carty PG, Walsh KA, De Gascun CF, Connolly MA, Smith SM, Oneill M, Ryan M, Harrington P (2021) Airborne transmission of SARS-CoV-2 via aerosols. Rev Med Virol 31(3):e2184. https://doi.org/10.1002/rmv.2184. (Epub 2020 Oct 26. PMID: 33105071; PMCID: PMC7645866)
Comunian S, Dongo D, Milani C, Palestini P (2020) Air pollution and Covid-19: the role of particulate matter in the spread and increase of Covid-19’s morbidity and mortality. Int J Environ Res Public Health 17(12):4487. https://doi.org/10.3390/ijerph17124487. (PMID: 32580440; PMCID: PMC7345938)
Dai T, Tegos GP, Rolz-Cruz G, Cumbie WE, Hamblin MR (2008) Ultraviolet C inactivation of dermatophytes: implications for treatment of onychomycosis. Br J Dermatol 158(6):1239–1246. https://doi.org/10.1111/j.1365-2133.2008.08549.x. (Epub 2008 Apr 10. PMID: 18410410; PMCID: PMC2808700)
Dai T, Kharkwal GB, Zhao J, St Denis TG, Wu Q, Xia Y, Huang L, Sharma SK, d’Enfert C, Hamblin MR (2011) Ultraviolet-C light for treatment of Candida albicans burn infection in mice. Photochem Photobiol 87(2):342–349. https://doi.org/10.1111/j.1751-1097.2011.00886.x. (Epub 2011 Feb 10. PMID: 21208209; PMCID: PMC3048910)
Ehsanifar M (2021) Airborne aerosols particles and COVID-19 transition. Environ Res 200:111752. https://doi.org/10.1016/j.envres.2021.111752. (Epub 2021 Jul 22. PMID: 34302822; PMCID: PMC8295061)
Enaki NA, Profir A, Ciobanu N, Bazgan S, Nistreanu A, Turcan M, Starodub E, Paslari T, Ristoscu C, Badiceanu M, Mihailescu IN (2018) Optical metamaterials for decontamination of translucent liquids and gases. J Phys D 51:385101–385111
Enaki NA, Starodub E, Paslari T, Turcan M, Bazgan S (2021) Close packing of elements of transparent metamaterials in UVC diapason and its influence on the decontamination efficiency. J Immunol Infect Dis 8(1):103
Enaki NA, Paslari T, Bazgan S, Starodub E, Munteanu I, Turcan M, Eremeev V, Profir A, Mihailescu IN (2022a) UVC radiation intensity dependence of pathogen decontamination rate: semiclassical theory and experiment. Eur Phys J plus 137(9):1047. https://doi.org/10.1140/epjp/s13360-022-03252-y. (Epub 2022 Sep 15. PMID: 36123970; PMCID: PMC9476412)
Enaki N, Paslari TR, Bazgan S, Starodub E, Marin T, Ţurcan M (2022b) The efficiency of screw channels in metamaterials for pathogen decontamination under ultraviolet C radiation. Int J Med Sci Clin Invent 6(9):6153–6156. https://doi.org/10.18535/ijmsci/v9i06.05
Enaki NA, Munteanu I, Paslari T, Turcan M, Starodub E, Bazgan S, Podoleanu D, Ristoscu C, Anghel S, Badiceanu M et al (2023) Topological avenue for efficient decontamination of large volumes of fluids via UVC irradiation of packed metamaterials. Materials 16:4559. https://doi.org/10.3390/ma16134559
Heßling M, Hönes K, Vatter P, Lingenfelder C (2020) Ultraviolet irradiation doses for coronavirus inactivation—review and analysis of coronavirus photoinactivation studies. GMS Hyg Infect Control 15:Doc08. https://doi.org/10.3205/dgkh000343
Jakočiūnas T, Holm LR, Verhein-Hansen J, Trusina A, Thon G (2013) Two portable recombination enhancers direct donor choice in fission yeast heterochromatin. PLoS Genet 9(10):e1003762. https://doi.org/10.1371/journal.pgen.1003762. (Epub 2013 Oct 24. PMID: 24204285; PMCID: PMC3812072)
Koschwanez JH, Foster KR, Murray AW (2011) Sucrose utilization in budding yeast as a model for the origin of undifferentiated multicellularity. PLoS Biol 9(8):e1001122. https://doi.org/10.1371/journal.pbio.1001122. Epub 2011 Aug 9. Erratum in: PLoS Biol. 2011 Aug;9(8). https://doi.org/10.1371/annotation/0b9bab0d-1d20-46ad-b318-d2229cde0f6f. Koschwanez, John H [corrected to Koschwanez, J H]; Foster, Kevin R [corrected to Foster, K R]; Murray, Andrew W [corrected to Murray, A W]. PMID: 21857801; PMCID: PMC3153487
Kowalski W (2009) UVGI disinfection theory. In: Kowalski W (ed) Ultraviolet germicidal irradiation handbook. Springer, Berlin, pp 17–50
Legras JL, Merdinoglu D, Cornuet JM, Karst F (2007) Bread, beer and wine: Saccharomyces cerevisiae diversity reflects human history. Mol Ecol 16(10):2091–2102. https://doi.org/10.1111/j.1365-294X.2007.03266.x. (PMID: 17498234)
Maier I (2010) Certificate inactivation of bacteria, viruses, and other pathogens by UV-C irradiation in the Leica cryostat product family. ecoscope Labor für Mikrobiologie und Ökotoxikologie. https://www.leicabiosystems.com/sites/default/files/media_product-download/2022-05/Leica_CM_UVC_Certificate_Bacteria.pdf
Mariita RM, Davis JH, Lottridge MM, Randive RV (2022) Shining light on multi-drug resistant Candida auris: ultraviolet-C disinfection, wavelength sensitivity, and prevention of biofilm formation of an emerging yeast pathogen. Microbiol Open 11(1):e1261. https://doi.org/10.1002/mbo3.1261. (PMID: 35212481; PMCID: PMC8767514)
Munteanu I (2023) Action of UV-C radiation for biomolecules inactivation, with application in diagnostics. Biomed J Sci Technol Res 52(1):43282–43287. https://doi.org/10.26717/BJSTR.2023.52.008192
Munteanu I, Turcan M, Starodub E, Bazgan S, Nistreanu A, Paslari T, Enaki NA (2022) Ultraviolet C radiation for disinfection and protection using periodical optical structure for dental implant. In: IEEE Xplore, 2023. 2022 E-health and bioengineering conference (EHB), 17–18 November 2022, Iasi, Romania, pp 1–4. https://doi.org/10.1109/EHB55594.2022.9991449
Ozcelik B (2007) Fungi/bactericidal and static effects of ultraviolet light in 254 and 354 nm wavelengths. Res J Microbiol 2:42–49
Patterson R, Rogiewicz A, Kiarie EG, Slominski BA (2023) Yeast derivatives as a source of bioactive components in animal nutrition: a brief review. Front Vet Sci 9:1067383. https://doi.org/10.3389/fvets.2022.1067383. (PMID: 36686164; PMCID: PMC9853299)
Ratcliff WC, Denison RF, Borrello M, Travisano M (2012) Experimental evolution of multicellularity. Proc Natl Acad Sci USA 109(5):1595–1600. https://doi.org/10.1073/pnas.1115323109. (Epub 2012 Jan 17. PMID: 22307617; PMCID: PMC3277146)
Reed NG (2010) The history of ultraviolet germicidal irradiation for air disinfection. Public Health Rep 125(1):15–27. https://doi.org/10.1177/003335491012500105. (PMID: 20402193; PMCID: PMC2789813)
Rosa CA, Gbor P (2006) Biodiversity and ecophysiology of yeasts series: the yeast handbook. Springer, Berlin, p 580
Shadloo-Jahromi A, Bavi O, Hossein Heydari M, Kharati-Koopaee M, Avazzadeh Z (2020) Dynamics of respiratory droplets carrying SARS-CoV-2 virus in closed atmosphere. Results Phys 19:103482. https://doi.org/10.1016/j.rinp.2020.103482. (Epub 2020 Oct 17. PMID: 33101885; PMCID: PMC7567668)
Stern RA, Al-Hemoud A, Alahmad B, Koutrakis P (2021) Levels and particle size distribution of airborne SARS-CoV-2 at a healthcare facility in Kuwait. Sci Total Environ 782:146799. https://doi.org/10.1016/j.scitotenv.2021.146799. (Epub 2021 Mar 27. PMCID: PMC8003456)
Talbot NJ (1997) Growing into the air. Curr Biol 7(2):R78–R81. https://doi.org/10.1016/s0960-9822(06)00041-8. (PMID: 9081668)
van Doremalen N, Bushmaker T, Morris DH, Holbrook MG, Gamble A, Williamson BN, Tamin A, Harcourt JL, Thornburg NJ, Gerber SI, Lloyd-Smith JO, de Wit E, Munster VJ (2020) Aerosol and surface stability of SARS-CoV-2 as compared with SARS-CoV-1. N Engl J Med 382(16):1564–1567. https://doi.org/10.1056/NEJMc2004973. (Epub 2020 Mar 17. PMID: 32182409; PMCID: PMC7121658)
Wong HJ, Mohamad-Fauzi N, Rizman-Idid M, Convey P, Alias SA (2019) Protective mechanisms and responses of micro-fungi towards ultraviolet-induced cellular damage. Polar Sci 20(Part 1):19–34. https://doi.org/10.1016/j.polar.2018.10.001. (ISSN 1873-9652)
Zuo YY, Uspal WE, Wei T (2020) Airborne transmission of COVID-19: aerosol dispersion, lung deposition, and virus–receptor interactions. ACS Nano 14(12):16502–16524. https://doi.org/10.1021/acsnano.0c08484. (Epub 2020 Nov 25. PMID: 33236896; PMCID: PMC7724984)
Acknowledgements
Subprogram code 011206 of the State University of Moldova.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The authors don’t have the financial, commercial, legal, or professional relationship with other organizations, or with the people working with them, that could influence their research.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
About this article
Cite this article
Munteanu, I., Starodub, E., Bazgan, S. et al. Ultraviolet C intensity dependence of decontamination efficiency for pathogens as function of repacked metamaterials with screw channels. Eur Biophys J 53, 133–145 (2024). https://doi.org/10.1007/s00249-024-01702-2
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00249-024-01702-2