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Acute necrotizing encephalopathy secondary to diphtheria, tetanus toxoid and whole-cell pertussis vaccination: diffusion-weighted imaging and proton MR spectroscopy findings

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Abstract

We present a previously healthy 6-month-old boy who was admitted to our hospital with lethargy, hypotonia and focal clonic seizures 6 days following diptheria, tetanus toxoid and whole-cell pertussis vaccination. A diagnosis of acute necrotising encephalopathy was made with the aid of MRI, including diffusion-weighted imaging and proton MR spectroscopy.

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Authors and Affiliations

  1. Department of Radiology, Baskent University Hospital, Ziya Gokalp, Cad 10, sok No: 45 Bahcelievler, Ankara, 06610, Turkey

    Hale Aydin, Esra Ozgul & Ahmet Muhtesem Agildere

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  1. Hale Aydin
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  2. Esra Ozgul
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  3. Ahmet Muhtesem Agildere
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Correspondence to Hale Aydin.

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Aydin, H., Ozgul, E. & Agildere, A.M. Acute necrotizing encephalopathy secondary to diphtheria, tetanus toxoid and whole-cell pertussis vaccination: diffusion-weighted imaging and proton MR spectroscopy findings. Pediatr Radiol 40, 1281–1284 (2010). https://doi.org/10.1007/s00247-009-1498-9

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  • DOI: https://doi.org/10.1007/s00247-009-1498-9

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