Abstract
The purpose of this study was to assess the prevalence of abnormal blood pressure in a population of school children during a 3-year follow-up period and its relationship with obesity. Anthropometric and blood pressure data were collected from a population of Italian school children during three consecutive years. During each year blood pressure measurements were repeated three times, at intervals of 1 week. A total of 564 school-children [311 boys; mean (SD) age 8.8 ± 1.4 years] were recruited. During each year, systolic and diastolic blood pressure decreased from visit 1 to visit 3 (p < 0.001). This was associated with a decline in the percentage of prehypertension/hypertension from visit 1 to visit 3. An abnormal blood pressure value in at least one study visit was found in 8.8–17 % of children, whereas the prevalence of hypertension at all three study visits was between 5.2 and 7.8 %, and that of prehypertension at all three visits was between 2.8 and 3.8 %. High blood pressure was more frequent in obese children. In this population of school children the percentage of prehypertension/hypertension remarkably varied when based on one versus three annual assessments, thus emphasizing the importance of repeated measurement before making a diagnosis of abnormal blood pressure. Adiposity was confirmed to be a determinant of high blood pressure.
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Bovet P, Gervasoni JP, Ross AG, Mkamba M, Mtasiwa DM, Lengeler C, Burnier M, Paccaud F (2003) Assessing the prevalence of hypertension in populations: are we doing it right? J Hypertens 21:509–517
Cacciari E, Milani S, Balsamo A, Spada E, Bona G, Cavallo L, Cerutti F, Gargantini L, Greggio N, Tonini G, Cicognani A (2006) Italian cross-sectional growth charts for height, weight and BMI (2 to 20 yr). J Endocrinol Invest 29:581–593
Chen X, Wang Y (2008) Tracking of blood pressure from childhood to adulthood: a systematic review and meta-regression analysis. Circulation 117:3171–3180
Chiolero A, Paccaud F, Bovet P (2007) Pre-hypertension and hypertension among adolescents of Switzerland. J Pediatr 151:e24–e25
Chiolero A, Cachat F, Burnier M, Paccaud F, Bovet P (2007) Prevalence of hypertension in schoolchildren based on repeated measurements and association with overweight. J Hypertens 25:2209–2217
Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, Jones DW, Materson BJ, Oparil S, Wright JT Jr, Roccella EJ (2003) Seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure. Hypertension 42:1206–1252
Cote AT, Harris KC, Panagiotopoulos C, Sandor GG, Devlin AM (2013) Childhood obesity and cardiovascular dysfunction. J Am Coll Cardiol 62:1309–1319
Daniels SR, Loggie JM, Khoury P, Kimball TR (1998) Left ventricular geometry and severe left ventricular hypertrophy in children and adolescents with essential hypertension. Circulation 97:1907–1911
Din-Dzietham R, Liu Y, Bielo MV, Shamsa F (2007) High blood pressure trends in children and adolescents in national surveys, 1963 to 2002. Circulation 116:1488–1496
Falkner B, Gidding SS, Ramirez-Garnica G, Wiltrout SA, West D, Rappaport EB (2006) The relationship of body mass index and blood pressure in primary care pediatric patients. J Pediatr 148:195–200
Farajian P, Panagiotakos DB, Risvas G, Micha R, Tsioufis C, Zampelas A (2015) Dietary and lifestyle patterns in relation to high blood pressure in children: the GRECO study. J Hypertens 33:1174–1181
Friedemann C, Heneghan C, Mahtani K, Thompson M, Perera R, Ward AM (2012) Cardiovascular disease risk in healthy children and its association with body mass index: systematic review and meta-analysis. BMJ 345:e4759
Fuentes RM, Notkola IL, Shemeikka S, Tuomilehto J, Nissinen A (2002) Tracking of systolic blood pressure during childhood: a 15-year follow-up population-based family study in eastern Finland. J Hypertens 20:195–202
Hansen ML, Gunn PW, Kaelber DC (2007) Underdiagnosis of hypertension in children and adolescents. JAMA 298:874–879
He Q, Ding ZY, Fong DY, Karlberg J (2000) Blood pressure is associated with body mass index in both normal and obese children. Hypertension 36:165–170
Huang RC, Burrows S, Mori TA, Oddy WH, Beilin LJ (2015) Lifecourse adiposity and blood pressure between birth and 17 years old. Am J Hypertens 28(8):1056–1063
Laitinen TT, Pahkala K, Magnussen CG, Viikari JS, Oikonen M, Taittonen L, Mikkila V, Jokinen E, Hutri-Kahonen N, Laitinen T, Kahonen M, Lehtimaki T, Raitakari OT, Juonala M (2012) Ideal cardiovascular health in childhood and cardiometabolic outcomes in adulthood: the Cardiovascular Risk in Young Finns Study. Circulation 125:1971–1978
Litwin M, Niemirska A, Sladowska J, Antoniewicz J, Daszkowska J, Wierzbicka A, Wawer ZT, Grenda R (2006) Left ventricular hypertrophy and arterial wall thickening in children with essential hypertension. Pediatr Nephrol 21:811–819
Lurbe E, Torro I, Garcia-Vicent C, Alvarez J, Fernandez-Fornoso JA, Redon J (2012) Blood pressure and obesity exert independent influences on pulse wave velocity in youth. Hypertension 60:550–555
Marcovecchio ML, Patricelli L, Zito M, Capanna R, Ciampani M, Chiarelli F, Mohn A (2006) Ambulatory blood pressure monitoring in obese children: role of insulin resistance. J Hypertens 24:2431–2436
McNiece KL, Poffenbarger TS, Turner JL, Franco KD, Sorof JM, Portman RJ (2007) Prevalence of hypertension and pre-hypertension among adolescents. J Pediatr 150:640–644
National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents (2004) The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics 114:555–576
Redwine KM, Daniels SR (2012) Prehypertension in adolescents: risk and progression. J Clin Hypertens (Greenwich) 14:360–364
Sorof JM, Alexandrov AV, Cardwell G, Portman RJ (2003) Carotid artery intimal-medial thickness and left ventricular hypertrophy in children with elevated blood pressure. Pediatrics 111:61–66
Sorof JM, Alexandrov AV, Garami Z, Turner JL, Grafe RE, Lai D, Portman RJ (2003) Carotid ultrasonography for detection of vascular abnormalities in hypertensive children. Pediatr Nephrol 18:1020–1024
Toledo-Corral CM, Ventura EE, Hodis HN, Weigensberg MJ, Lane CJ, Li Y, Goran MI (2009) Persistence of the metabolic syndrome and its influence on carotid artery intima media thickness in overweight Latino children. Atherosclerosis 206:594–598
Urbina EM, Khoury PR, McCoy C, Daniels SR, Kimball TR, Dolan LM (2011) Cardiac and vascular consequences of pre-hypertension in youth. J Clin Hypertens (Greenwich) 13:332–342
Zhang YX, Wang SR (2015) Distribution of subcutaneous fat and the relationship with blood pressure in obese children and adolescents in Shandong, China. Paediatr Perin Epidem 29:156–161
Acknowledgments
We would like to thank all study participants, their families and the personnel of the schools participating to the study. M.L.M. is the recipient of the 2014 “L’Oréal Italia per le Donne e la Scienza” (For Women in Science) fellowship.
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Marcovecchio, M.L., Mohn, A., Diddi, G. et al. Longitudinal Assessment of Blood Pressure in School-Aged Children: A 3-Year Follow-Up Study. Pediatr Cardiol 37, 255–261 (2016). https://doi.org/10.1007/s00246-015-1271-9
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DOI: https://doi.org/10.1007/s00246-015-1271-9