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Epidemiology and composition of upper urinary tract lithiasis in Senegalese population: a multicenter retrospective study

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Abstract

Urolithiasis is a major public health issue due to its increasing prevalence. The objective of this study was to describe the spectrophotometric profile of upper urinary tract stones (UTS) in Senegal. We conducted a multicenter retrospective study of all patients treated for upper UTS whose chemical composition was analyzed from January 2014 to January 2020 in eight regions of Senegal. Socio-demographic, clinical, paraclinical, and prognosis data were collected and analyzed. Three hundred and thirty-four patients were included in this study with a mean age of 46.3 ± 18.4 years and a sex ratio of 1.38. About one-third of patients (31.1%) had a body mass index > 25 kg/m2 and 74.2% presented with lumbar pain was the main clinical symptom. Calcium oxalate and calcium phosphate stones were the predominant types found, respectively, in 37.7% and 24.5% of patients. Uric acid was the main stone constituent in 18.6% of patients and struvites represented 14.7% of cases. Stones were located in the renal calyces and pelvis in 71.2% of cases. Surgical lithotomy was performed in 62.7% of patients for UTS extraction. Upper UTS are frequent condition in Senegalese with predominance of males and young adults. Calcium and uric acid stones are the main types. Preventive dietary and lifestyle measures are needed to reduce their burden.

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Acknowledgements

The authors thank Centre d'Excellence Africain Environnement&Santé (CEA-AGIR), Laboratoire Bio24, IPD and SulunLab for their support.

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Authors and Affiliations

  1. Nephrology and Dialysis, Regional Hospital of Kedougou, Dakar, Senegal

    Ndongo Modou & Seck Sidy Mohamed

  2. Nephrology and Dialysis Department, Regional Hospital of Ndioum, Dakar, Senegal

    Dahaba Mohamed

  3. Nephrology and Dialysis Department, Military Hospital of Ouakam, Dakar, Senegal

    L. Motoula Latou

  4. Urology Department, Hopital Principal, Dakar, Senegal

    Kane Racine

  5. Urology Department, Idrissa Pouye General Hospital, Dakar, Senegal

    Niang Lamine

  6. Faculty of Health Sciences, IRL-3189/ESS/UGB/CNRS/UCAD/CNRST/USTB, University Gaston Berger, Saint-Louis, Senegal

    Doupa Dominique & Seck Sidy Mohamed

  7. CEA AGIR, Cheikh Anta DIOP University, Dakar, Senegal

    Seck Sidy Mohamed

  8. Nephrology Department, Faculty of Health Sciences, University Gaston Berger, Route de Ngalléle, Sanar, BP 234, Saint-Louis, Sénégal

    Seck Sidy Mohamed

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  1. Ndongo Modou
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  2. Dahaba Mohamed
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  3. L. Motoula Latou
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  4. Kane Racine
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  5. Niang Lamine
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  6. Doupa Dominique
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  7. Seck Sidy Mohamed
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Contributions

M.D., R.K, L.N and S.M.S contributed to data collection and analysis M.D, M.N, L.M.L, D.D, A.D.D and S.M.S wrote the first draft of the manuscript. All authors reviewed the manuscript.

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Correspondence to Seck Sidy Mohamed.

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Modou, N., Mohamed, D., Motoula Latou, L. et al. Epidemiology and composition of upper urinary tract lithiasis in Senegalese population: a multicenter retrospective study. Urolithiasis 52, 4 (2024). https://doi.org/10.1007/s00240-023-01498-4

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  • DOI: https://doi.org/10.1007/s00240-023-01498-4

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