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Silica gel impregnated with deep eutectic solvent-based matrix solid-phase dispersion followed by high-performance liquid chromatography for extraction and detection of triazine herbicides in brown sugar

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Abstract

A novel method was developed to determine six triazine herbicides from brown sugar samples using matrix solid-phase dispersion (MSPD) based on silica gel impregnated with deep eutectic solvent (DES) followed by high-performance liquid chromatography with photodiode array detector (HPLC/PDA). Several factors involved in the MSPD procedure such as DES type, DES content in impregnated silica gel, adsorbent-to-sample mass ratio, type and volume of washing solvent, type and volume of eluent, and grinding time were screened using single-factor experiments and then optimized using Box-Behnken design to accomplish the highest recoveries. The above method demonstrated a good linear range (20–1000 μg kg−1) with a determination coefficient exceeding 0.9962, low limits of determination (1.59–3.77 μg kg−1), acceptable limits of quantifications, and acceptable spiking recoveries (95.0–101.7%) for six triazines under optimized conditions. The proposed MSPD-HPLC/PDA method is a convenient, effective, and sensitive method for rapidly isolating and quantifying six triazines from brown sugar.

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Acknowledgements

The authors gratefully acknowledge the financial supports by Guangdong Academy of Sciences’ Project of Science and Technology Development under Grant numbers 2020GDASYL-20200103069.

Funding

This work was supported by Guangdong Academy of Sciences’ Project of Science and Technology Development (Grant number: 2020GDASYL-20200103069).

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Authors and Affiliations

  1. Institute of Bioengineering and Medical Engineering, Guangdong Academy of Sciences, Guangzhou, 510316, People’s Republic of China

    Peng Li, Dongting Huang, Jingjie Tang, Pingjun Zhang & Fei Meng

  2. Guangdong Engineering Research Center for Sugar Technology, Guangzhou, 510316, People’s Republic of China

    Peng Li, Dongting Huang, Jingjie Tang, Pingjun Zhang & Fei Meng

Authors
  1. Peng Li
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  2. Dongting Huang
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  3. Jingjie Tang
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  4. Pingjun Zhang
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  5. Fei Meng
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Contributions

Conceptualization: Peng Li; data curation: Peng Li; formal analysis: Peng Li, Jingjie Tang; investigation: Dongting Huang; methodology: Jingjie Tang; resources: Pingjun Zhang; supervision: Pingjun Zhang; validation: Jingjie Tang, Fei Meng; visualization: Peng Li, Dongting Huang; writing — original draft: Peng Li; writing — review and editing: Peng Li, Fei Meng.

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Correspondence to Fei Meng.

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Li, P., Huang, D., Tang, J. et al. Silica gel impregnated with deep eutectic solvent-based matrix solid-phase dispersion followed by high-performance liquid chromatography for extraction and detection of triazine herbicides in brown sugar. Anal Bioanal Chem 414, 3497–3505 (2022). https://doi.org/10.1007/s00216-022-03970-3

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  • DOI: https://doi.org/10.1007/s00216-022-03970-3

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