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Renovating the chromoionophores and detection modes in carrier-based ion-selective optical sensors

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Abstract

Ion-selective optical sensing is an important branch of analytical and bioanalytical chemistry. Conventional ion-selective optodes are based on H+ chromoionophores. These sensors are known to be pH dependent and usually operated in a passive mode. In view of the applications in complex real samples, the sensors must exhibit not only excellent chemical selectivity but also the ability to eliminate the optical background interference such as autofluorescence and light scattering. In this article, recent advances to renovate the chromoionophores and detection modes to overcome the pH cross-response and to eliminate the background optical interference are summarized. Topics include sensors based on solvatochromic dyes, alternative chromoionophores, photoswitchable sensors, upconverting nanoparticles, luminescence decay time, and others.

Ion-selective optical sensing is an important branch of analytical and bioanalytical chemistry. In view of the applications in complex real samples, this article highlighted recent advances to renovate the chromoionophores and detection modes to overcome the drawbacks from the pH cross-response and background optical interference

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Acknowledgments

The author thanks the Swiss National Science Foundation (SNSF) and the University of Geneva for financial support. The author thanks Professor Eric Bakker for providing the academic environment, and the reviewers for their comments and suggestions.

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  1. Department of Inorganic and Analytical Chemistry, University of Geneva, Quai Ernest Ansermet 30, 1211, Geneva 4, Switzerland

    Xiaojiang Xie

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Published in the topical collection featuring Young Investigators in Analytical and Bioanalytical Science with guest editors S. Daunert, A. Baeumner, S. Deo, J. Ruiz Encinar, and L. Zhang.

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Xie, X. Renovating the chromoionophores and detection modes in carrier-based ion-selective optical sensors. Anal Bioanal Chem 408, 2717–2725 (2016). https://doi.org/10.1007/s00216-016-9406-2

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