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Roles of bacterial membrane vesicles

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Abstract

Outer membrane vesicles (OMVs) are released from the outer membrane of Gram-negative bacteria. Moreover, Gram-positive bacteria also produce membrane-derived vesicles. As OMVs transport several bacterial components, especially from the cell envelope, their interaction with the host cell, with other bacteria or as immunogens, have been studied intensely. Several functions have been ascribed to OMVs, especially those related to the transport of virulence factors, antigenic protein composition, and development as acellular vaccines. In this work, we review some of the recent findings about OMVs produced by specific pathogenic bacterial species.

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Acknowledgments

This work was funded by CONACYT CB-2011-01 No. 169259, SIP-IPN 20131610, SIP-IPN 20144471, and Proyecto de investigacion en apoyo a la consolidacion de profesores del Instituto Politecnico Nacional, con nivel de candidato a investigador Nacional ICYT-DF/IPN. EDAC and MGAV were supported by CONACYT and PIFI-IPN scholarships. ACR, JCCD and EOLV were supported by fellowships from COFAA, SIP-EDI, and SNI-CONACYT. ACR was supported by semestre sabatico agosto-enero 2013-2014 ENCB-IPN.

Conflict of interest

The authors declare that they have no competing interests in relation to this work.

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Authors and Affiliations

  1. Departamento de Microbiología. Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Prol. Carpio y Plan de Ayala s/n, Col. Sto. Tomás, CP 11340, Mexico, D.F., Mexico

    Eric Daniel Avila-Calderón, Minerva Georgina Araiza-Villanueva, Juan Carlos Cancino-Diaz, Edgar Oliver López-Villegas & Araceli Contreras-Rodríguez

  2. Center for Molecular Medicine and Infectious Diseases, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, VA, 24061, USA

    Nammalwar Sriranganathan & Stephen M. Boyle

Authors
  1. Eric Daniel Avila-Calderón
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  2. Minerva Georgina Araiza-Villanueva
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  3. Juan Carlos Cancino-Diaz
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  4. Edgar Oliver López-Villegas
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  5. Nammalwar Sriranganathan
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  6. Stephen M. Boyle
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  7. Araceli Contreras-Rodríguez
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Corresponding author

Correspondence to Araceli Contreras-Rodríguez.

Additional information

Communicated by Erko Stackebrandt.

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Avila-Calderón, E.D., Araiza-Villanueva, M.G., Cancino-Diaz, J.C. et al. Roles of bacterial membrane vesicles. Arch Microbiol 197, 1–10 (2015). https://doi.org/10.1007/s00203-014-1042-7

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  • DOI: https://doi.org/10.1007/s00203-014-1042-7

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