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Der akute Thoraxschmerz

Acute chest pain

  • Schwerpunkt: Internistische Notfallmedizin
  • Published:
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Zusammenfasssung

Akuter Thoraxschmerz ist die Hauptursache stationärer Aufnahmen weltweit und verbraucht beträchtliche finanzielle und Krankenhaus-Ressourcen für Diagnose und Versorgung. Nach wie vor ist ein nicht diagnostizierter akuter Myokardinfarkt mit einem ungünstigen Verlauf verbunden und stellt einen der häufigsten Anlässe für einen Rechtsstreit in den Vereinigten Staaten dar. Der vorliegende Beitrag gibt eine Zusammenfassung der Kennzeichen des kardialen und nichtkardialen Thoraxschmerzes, bietet einen Überblick über diagnostische Algorithmen und erläutert die wichtigen Differenzialdiagnosen.

Abstract

Acute chest pain is the leading cause of hospital admissions worldwide and absorbs extensive financial and hospital resources for diagnosis and management. A missed diagnosis of acute myocardial infarction is still associated with a poor outcome and represents one of the most common reasons for lawsuits in the USA. The present article gives a summary on the features of cardiac and non-cardiac chest pain, provides an overview of diagnostic algorithms, and points out the important differential diagnoses.

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Literatur

  1. Anonymous (2002) Guidelines on diagnosis and management of acute pulmonary embolism. Task Force on Pulmonary Embolism, European Society of Cardiology. Eur Heart J 21: 1301–1336

    Google Scholar 

  2. Atallah FN, Riu BM, Nguyen LB, Seguin PO, Fourcade OA (2004) Boerhaave’s syndrome after postoperative vomiting. Anesth Analg 98: 1164–1166

    Article  PubMed  Google Scholar 

  3. Brauer RB, Libermann-Meffert D, Stein HJ (1997) Boerhaave’s syndrome: analysis of the literature and report of 18 new cases. Dis Esophagus 10: 64–68

    CAS  PubMed  Google Scholar 

  4. Braunwald E, Antman E, Beasley J (2002) ACC/AHA guideline update for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction- Summary article: A report of the American College of Cardiology/American Heart Association task force on practice guidelines (Committee on the Management of Patients With Unstable Angina). J Am Coll Cardiol 40: 1366–1374

    Google Scholar 

  5. Diamond GA, Forrester JS (1979) Analysis of probability as an aid in the clinical diagnosis of coronary-artery disease. N Engl J Med 300: 1350–1358

    CAS  PubMed  Google Scholar 

  6. Dietz R, B Rauch (2003) Leitlinie zur Diagnose und Behandlung der chronischen koronaren Herzerkrankung der Deutschen Gesellschaft für Kardiologie — Herz- und Kreislaufforschung (DGK). In Kooperation mit der Deutschen Gesellschaft für Prävention und Rehabilitation von Herz- Kreislauferkrankungen (DGPR) und der Deutschen Gesellschaft für Thorax-, Herz- und Gefäßchirurgie DGTHG. Z Kardiol 92: 501–521

    CAS  PubMed  Google Scholar 

  7. Erhardt L, Herlitz J, Bossaert L et al. (2002) Aetiology to chest pain in various clinical settings, Task force report: management of chest pain. Eur Heart J 23: 1153–1176

    Article  CAS  PubMed  Google Scholar 

  8. Ferrari E, Imbert A, Chevalier T, Mihoubi A, Morand P, Baudouy M (1997) The ECG in pulmonary embolism. Predictive value of negative T waves in precordial leads — 80 case reports. Chest 111: 537–543

    CAS  PubMed  Google Scholar 

  9. Giannitsis E, Katus HA (2002) Acute posterior myocardial infarct. A typical diagnostic error. Internist (Berl) 43: 618–623

    Google Scholar 

  10. Giannitsis E, Muller-Bardorff M, Kurowski V, Weidtmann B, Wiegand U, Kampmann M, Katus HA (2000) Independent prognostic value of cardiac troponin T in patients with confirmed pulmonary embolism. Circulation 102: 211–217

    CAS  PubMed  Google Scholar 

  11. Goldhaber SZ, Visani L, De Rosa M (1999) Acute pulmonary embolism: clinical outcomes in the International Cooperative Pulmonary Embolism Registry (ICOPER) Lancet 353: 1386–1389

    Google Scholar 

  12. Hagan PG, Nienaber CA, Isselbacher EM (2000) The international registry of acute aortic dissection (IRAD): new insights into an old disease. JAMA 283: 897–903

    Article  CAS  PubMed  Google Scholar 

  13. Hamm CW (2004) Deutsche Gesellschaft für Kardiologie — Herz- und Kreislaufforschung. Leitlinien: Akutes Koronarsyndrom (ACS) Teil 1: Akutes Koronarsyndrom ohne persistierende ST-Strecken-Hebung. Z Kardiol 93: 72–90

    Article  CAS  PubMed  Google Scholar 

  14. Hamm CW (2004) Deutsche Gesellschaft für Kardiologie — Herz- und Kreislaufforschung. Leitlinien: Akutes Koronarsyndrom (ACS) Teil 2: Akutes Koronarsyndrom mit ST-Hebung. Z Kardiol 93: 324–341

    Article  CAS  PubMed  Google Scholar 

  15. Henrikson CA, Howell EE, Bush DE, Miles JS, Meininger GR, Friedlander T (2003) Chest pain relief by nitroglycerin does not predict active coronary artery disease. Ann Intern Med 139: 979–986

    Google Scholar 

  16. Kasper W, Konstantinides S, Geibel A et al. (1997) Management strategies and determinants of outcome in acute major pulmonary embolism: results of a multicenter registry. J Am Coll Cardiol 30: 1165–1171

    Article  CAS  PubMed  Google Scholar 

  17. Knockaert DC, Buntinx F (2002) Chest pain in the emergency department: the broad spectrum of causes. Eur J Emerg Med 9: 25–30

    Article  CAS  PubMed  Google Scholar 

  18. Kurz K, Katus HA, Giannitsis E (2004) Ischämiediagnostik. Herz 29: 575–581

    Article  PubMed  Google Scholar 

  19. Langer A, Freeman MR, Armstrong PW (1989) ST segment shift in unstable angina: pathophysiology and association with coronary anatomy and hospital outcome. J Am Coll Cardiol 13: 1495–1502

    CAS  PubMed  Google Scholar 

  20. Lee TH, Rouan GW, Weisberg MC et al. (1987) Clinical characteristics and natural history of patients with acute myocardial infarction sent home from the emergency room. Am J Cardiol 60: 219–224

    Article  CAS  PubMed  Google Scholar 

  21. Lemke T, Jagminas L (1999) Spontaneous esophageal rupture: a frequently missed diagnosis. Am Surg 65: 449–452

    CAS  PubMed  Google Scholar 

  22. Ludwig J, Kienzle GD (1978) Pneumothorax in a large autopsy population. A study of 77 cases. Am J Clin Pathol 70: 24–26

    CAS  PubMed  Google Scholar 

  23. Mehta RH, O’Gara PT, Bossone E (2002) Acute type A aortic dissection in the elderly: clinical characteristics, management, and outcomes in the current era. J Am Coll Cardiol 40: 685–692

    Google Scholar 

  24. Meignan M, Rosso J, Gauthier H et al. (2000) Systematic lung scans reveal a high frequency of silent pulmonary embolism in patients with proximal deep venous thrombosis. Arch Intern Med 160: 159–164

    Article  CAS  PubMed  Google Scholar 

  25. Melton LJ, Hepper NG, Offord KP (1979) Incidence of spontaneous pneumothorax in Olmstead County, Minnesota: 1950 to 1974. Am Rev Respir Dis 120: 1379–1382

    PubMed  Google Scholar 

  26. Meyer FJ, Jöckel J, Borst MM (2000) Management von Pneumothorax und Hämatothorax auf der internistischen Intensivstation. Intensivmed 37: 334–340

    Article  Google Scholar 

  27. Meyer T, Binder L, Hruska N, Luthe H, Buchwald AB (2000) Cardiac troponin I elevation in acute pulmonary embolism is associated with right ventricular dysfunction. J Am Coll Cardiol 36: 1632–1636

    Article  CAS  PubMed  Google Scholar 

  28. Miltenburg-van Zijl AJ, Simoons ML, Veerhoek RJ, Bossuyt PM (1995) Incidence and follow-up of Braunwald subgroups in unstable angina pectoris. J Am Coll Cardiol 25(6): 1286–1292

    Article  PubMed  Google Scholar 

  29. Nienaber CA, Eagle KA (2003) Aortic dissection: new frontiers in diagnosis and management: Part I: from etiology to diagnostic strategies. Circulation 108: 628–635

    Article  PubMed  Google Scholar 

  30. Pope J, Aufderheide T, Ruthazer R (2000) Missed diagnoses of acute cardiac ischemia in the emergency department. NEJM 342: 1163–1170

    Article  CAS  PubMed  Google Scholar 

  31. Ryan TJ, Antman EM, Brooks NH et al. (1999) 1999 update: ACC/AHA guidelines for the management of patients with acute myocardial infarction. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Acute Myocardial Infarction). J Am Coll Cardiol 34: 890–911

    Article  CAS  PubMed  Google Scholar 

  32. Sreeram N, Cheriex EC, Smeets JL, Gorgels AP, Wellens HJ (1994) Value of the 12-lead electrocardiogram at hospital admission in the diagnosis of pulmonary embolism. Am J Cardiol 73: 298–303

    Article  CAS  PubMed  Google Scholar 

  33. Stein PD, Henry JW (1997) Clinical characteristics of patients with acute pulmonary embolism stratified according to their presenting syndromes. Chest 112: 974–979

    CAS  PubMed  Google Scholar 

  34. Stein PD, Terrin ML, Hales CA (1991) Clinical, laboratory, roentgenographic and electrocardiographic findings in patients with acute pulmonary embolism and no pre-existing cardiac or pulmonary disease. Chest 100: 598–603

    CAS  PubMed  Google Scholar 

  35. Walker WS, Cameron EW, Walbaum PR (1985) Diagnosis and management of spontaneous transmural rupture of the oesophagus (Boerhaave’s syndrome). Br J Surg 72: 204–207

    CAS  PubMed  Google Scholar 

  36. Wells PS, Anderson DR, Rodger M (2000) Derivation of a simple model to categorize patients probability of pulmonary embolism: Increasing the model’s utility with the SimpliRED D-dimer. Thromb Haemost 83: 416–420

    CAS  PubMed  Google Scholar 

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Kurz, K., Katus, H.A. & Giannitsis, E. Der akute Thoraxschmerz. Internist 46, 957–964 (2005). https://doi.org/10.1007/s00108-005-1456-z

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  • DOI: https://doi.org/10.1007/s00108-005-1456-z

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