Skip to main content
Log in

Hyperbare Oxygenierung bei Kohlenmonoxidintoxikation

Fallbericht einer schweren Intoxikation durch Autoabgase

Hyperbaric oxygen for carbon monoxide poisoning

Case report of severe poisoning due to exhaust fumes

  • Kasuistiken
  • Published:
Der Anaesthesist Aims and scope Submit manuscript

Zusammenfassung

Ein Patient mit schwerer Kohlenmonoxidvergiftung [Carboxyhämoglobin- (CO-Hb-)Konzentration 82%] wird nach Rettung und Transport an ein Druckkammerzentrum einer hyperbaren Oxygenierungs- (HBO-)Behandlung zugeführt. Während der Dekompression kommt es infolge massiver Acidose, Hyperkaliämie, Hämokonzentration und erhöhtem CO-Hb zum Herz-Kreislauf-Stillstand. Nach erfolgreicher Reanimation wird die HBO-Behandlung zur Prophylaxe neurologischer Spätfolgen im Anschluss an die kardiopulmonale Diagnostik bei fortbestehender Katecholaminpflichtigkeit fortgeführt. Drei Monate nach Abschluss der Behandlung bestehen keine neurologischen Folgeschäden.

Abstract

After rescue and transport a patient with severe carbon monoxide poisoning (CO-Hb concentration 82%) was treated by hyperbaric oxygen (HBO) therapy in a pressure chamber. During decompression the patient suffered cardiac arrest due to massive acidosis, hyperpotassaemia, haemoconcentration and elevated CO-Hb level. After successful resuscitation and cardiopulmonary diagnostics, HBO therapy was continued for prophylactic treatment of delayed neurological sequelae. Three months after completing treatment and discharge from hospital there were no neurological sequelae.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Abb. 1
Abb. 2
Abb. 3

Literatur

  1. Gandini C, Broccolino M, Scarpini S et al (1995) Heart damage caused by carbon monoxide poisoning. In: Oriani G, Marroni A, Wattel F (eds) Handbook on hyperbaric medicine. Springer, Berlin Heidelberg New York, pp 312–330

  2. Barker SJ, Curry J, Redford D, Morgan S (2006) Measurement of carboxyhemoglobin and methemoglobin by pulse oximetry. Anesthesiology 105:892–897

    Article  PubMed  Google Scholar 

  3. Masimo Corporation Website. Rad-57 Pulse CO-oximeter (2006). http://www.masimo.com/rad-57/index.htm

  4. Pace N, Strajman E, Walker EL (1950) Acceleration of carbon monoxide elimination in man by high pressure oxygen. Science 111:652–654

    Article  PubMed  CAS  Google Scholar 

  5. Satran D, Henry CR, Adkinson C et al (2005) Cardiovascular manifestations of moderate to severe carbon monoxide poisoning. J Am Coll Cardiol 45:1513–1516

    Article  PubMed  CAS  Google Scholar 

  6. Henry CR, Satran D, Lindgren B et al (2006) Myocardial injury and long-term mortality following moderate to severe carbon monoxide poisoning. JAMA 295:398–402

    Article  PubMed  CAS  Google Scholar 

  7. Thom SR, Bhopale VM, Han ST et al (2006) Intravascular neutrophil activation due to carbon monoxide poisoning. Am J Respir Crit Care Med 174:1239–1248

    Article  PubMed  CAS  Google Scholar 

  8. Brown SD, Piantadosi CA (1992) Recovery of energy metabolism in rat brain after carbon monoxide hypoxia. J Clin Invest 89:666–672

    Article  PubMed  CAS  Google Scholar 

  9. Thom SR, Bhopale VM, Fisher D et al (2004) Delayed neuropathology after carbon monoxide poisoning is immune-mediated. Proc Natl Acad Sci U S A 101(37):13660–13665

    Article  PubMed  CAS  Google Scholar 

  10. Thom SR (1993) Functional inhibition of leukocyte B2 integrins by hyperbaric oxygen in carbon monoxide-mediated brain injury in rats. Toxicol Appl Pharmacol 123(2):248–256

    Article  PubMed  CAS  Google Scholar 

  11. Weaver LK, Hopkins RO, Chan KJ et al (2002) Hyperbaric oxygen for acute carbon monoxide poisoning. N Engl J Med 347:1057–1067

    Article  PubMed  CAS  Google Scholar 

Download references

Interessenkonflikt

Es besteht kein Interessenkonflikt.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to M. Erdmann.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Erdmann, M., Schöppenthau, H. & Büttner, J. Hyperbare Oxygenierung bei Kohlenmonoxidintoxikation. Anaesthesist 58, 589–593 (2009). https://doi.org/10.1007/s00101-009-1518-z

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00101-009-1518-z

Schlüsselwörter

Keywords

Navigation