Skip to main content

Advertisement

Log in

Short-term outcome following significant trauma: increasing age per se has only a relatively low impact

  • Original Article
  • Published:
European Journal of Trauma and Emergency Surgery Aims and scope Submit manuscript

Abstract

Purpose

Ongoing demographic changes go hand in hand with an increasing number of elderly injured. Given the conflicting literature we wanted to know how much age per se, apart from other factors, actually explains the outcome for elderly trauma patients.

Methods

Retrospective analysis of prospectively collected data on all significantly injured (new injury severity score, NISS  ≥ 8) adult patients treated at a Swiss trauma center between 01.01.2010 and 31.12.2017. The association of age and other demographic, trauma or treatment-related variables on parameters of short-term outcome was examined using uni- and multivariate analyses (mean ± SD; R2; p < 0.05).

Results

2692 consecutive patients (33.4% female; mean age 58.1 ± 21.7; hospital mortality 10.1%) were studied. Detailed analysis of quinquennial age groups demonstrated a significant decline in outcome with regard to mortality or return-to-home rate following hospital discharge after the age of 60 years (p < 0.001). In univariate analysis, age explained 4.6% and the number of years ≥ 60 5.9% of hospital mortality. In multivariate analysis, the investigated demographic, trauma or treatment-related parameters contributed at 36.5% to prediction of mortality, age added another 1.5% and number of years  ≥ 60 another 2.1% (R2).

Conclusion

This monocenter evaluation showed a significant decline in short-term outcome and an increase in hospital resource requirements by the trauma patients investigated after the age of 60 years. Even so, after controlling for demographic, injury and treatment variables, age per se only added less than 2% to the prediction of hospital mortality.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Kehoe A, Smith JE, Edwards A, Yates D, Lecky F, et al. The changing face of major trauma in the UK. Emerg Med J. 2015;32:911–5.

    CAS  PubMed  Google Scholar 

  2. De Vries R, Reininga IHF, Pieske O, Lefering R, El Moumni M, Wendt K, et al. Injury mechanisms, patterns and outcomes of older polytrauma patients - An analysis of the Dutch Trauma Registry. PLoS ONE. 2018;13:e0190587.

    PubMed  PubMed Central  Google Scholar 

  3. WHO Global Report on Falls Prevention in Older Age. Ageing and Life Course, Family and Community Health, 2018, World Health Organisation Accessed Feb 14 2019

  4. Bhattacharya B, Maung A, Schuster K, Davis KA, et al. The older they are the harder they fall: Injury patterns and outcomes by age after ground falls. Injury. 2016;47:1955–9.

    PubMed  Google Scholar 

  5. Alberdi F, Garcia I, Atutxa L, Zabarte M, et al. Epidemiología del trauma grave. Med Intensiva. 2014;38:580–8.

    CAS  PubMed  Google Scholar 

  6. Braun BJ, Holstein J, Fritz T, Veith NT, Herath S, Mörsdorf P, Pohlemann T, et al. Polytrauma in the elderly: a review. EFORT Open Rev. 2016;1:146–51.

    PubMed  PubMed Central  Google Scholar 

  7. Dimitriou R, Calori GM, Giannoudis PV, et al. Polytrauma in the elderly: specific considerations and current concepts of management. Eur J Trauma Emerg Surg. 2011;37:539–48.

    CAS  PubMed  Google Scholar 

  8. Hashmi A, Ibrahim-Zada I, Rhee P, Aziz H, Fain MJ, Friese RS, Joseph B, et al. Predictors of mortality in geriatric trauma patients: a systematic review and meta-analysis. J Trauma Acute Care Surg. 2014;76:894–901.

    PubMed  Google Scholar 

  9. Goodmanson NW, Rosengart MR, Barnato AE, Sperry JL, Peitzman AB, Marshall GT, et al. Defining geriatric trauma: When does age make a difference? Surgery. 2012;152:668–75.

    PubMed  Google Scholar 

  10. Caterino JM, Valasek T, Werman HA, et al. Identification of an age cutoff for increased mortality in patients with elderly trauma. Am J Emerg Med. 2010;28:151–8.

    PubMed  Google Scholar 

  11. Lefering R, Huber-Wagner S, Nienaber U, Maegele M, Bouillon B, et al. Update of the trauma risk adjustment model of the TraumaRegister DGU™: the Revised Injury Severity Classification, version II. Crit Care. 2014;18:476.

    PubMed  PubMed Central  Google Scholar 

  12. Zhao ZF, Wolf SE, Nakonezny PA, Minhajuddin A, Rhodes RL, Paulk ME, Phelan HA, et al. Estimating geriatric mortality after injury using age, injury severity, and performance of a transfusion: The geriatric trauma outcome score. J Palliat Med. 2015;18:677–81.

    PubMed  PubMed Central  Google Scholar 

  13. Hranjec T, Sawyer RG, Young JS, Swenson BR, Calland JF, et al. Mortality factors in geriatric blunt trauma patients: creation of a highly predictive statistical model for mortality using 50,765 consecutive elderly trauma admissions from the National Sample Project. Am Surg. 2012;78:1369–75.

    PubMed  PubMed Central  Google Scholar 

  14. Kuhls DA, Malone DL, McCarter RJ, Napolitano LM, et al. Predictors of mortality in adult trauma patients: the physiologic trauma score is equivalent to the Trauma and Injury Severity Score. J Am Coll Surg. 2002;194:695–704.

    PubMed  Google Scholar 

  15. Caterino JM, Brown NV, Hamilton MW, Ichwan B, Khaligdina S, Evans DC, Darbha S, Panchal AR, Shah MN. Effect of geriatric-specific trauma triage criteria on outcomes in injured older adults, a statewide retrospective cohort study. J Am Geriatr Soc. 2016;64:1944–51.

    PubMed  PubMed Central  Google Scholar 

  16. Gross T, Morell S, Amsler F, et al. Longer-term quality of life following major trauma: age only significantly affects outcome after the age of 80 years. Clin Interv Aging. 2018;13:773–85.

    PubMed  PubMed Central  Google Scholar 

  17. Collins CE, Witkowski ER, Flahive JM, Anderson FE Jr, Santry HP, et al. Effect of preinjury warfarin use on outcomes after head trauma in Medicare beneficiaries. Am J Surg. 2014;208:544–9.

    PubMed  PubMed Central  Google Scholar 

  18. Ulvik A, Wentzel-Larsen T, Flaatten H, et al. Trauma patients in the intensive care unit: short- and long-term survival and predictors of 30-day mortality. Acta Anaesthesiol Scand. 2007;51:171–7.

    CAS  PubMed  Google Scholar 

  19. Grossman MD, Miller D, Scaff DW, Arcona S, et al. When is an elder old? effect of preexisting conditions on mortality in geriatric trauma. J Trauma. 2002;52:242–6.

    PubMed  Google Scholar 

  20. Nirula R, Gentilello LM, et al. Futility of resuscitation criteria for the “young” old and the “old” old trauma patient: a national trauma data bank analysis. J Trauma. 2004;57:37–41.

    PubMed  Google Scholar 

  21. Chang WH, Tsai SH, Su YJ, Huang CH, Chang KS, Tsai CH, et al. Trauma mortality factors in the elderly population. Int J Gerontol. 2008;1:11–7.

    Google Scholar 

  22. Hollis S, Lecky F, Yates DW, Woodford M, et al. The effect of pre-existing medical conditions and age on mortality after injury. J Trauma. 2006;61:1255–60.

    PubMed  Google Scholar 

  23. Fröhlich M, Lefering R, Probst C, Paffrath T, Schneider MM, Maegele M, Sakka SG, Bouillon B, Wafaisade A, et al. Epidemiology and risk factors of multiple-organ failure after multiple trauma: an analysis of 31,154 patients from the TraumaRegister DGU. J Trauma Acute Care Surg. 2014;76:921–8.

    PubMed  Google Scholar 

  24. Zietlow SP, Capizzi PJ, Bannon MP, Farnell MB, et al. Multisystem geriatric trauma. J Trauma. 1994;37:985–8.

    CAS  PubMed  Google Scholar 

  25. Jennett B, Bond M, et al. Assessment of outcome after severe brain damage: a practical scale. Lancet. 1975;1(7905):480–4.

    CAS  PubMed  Google Scholar 

  26. Charlson ME, Pompei P, Ales KL, MacKenzie CR, et al. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chron Dis. 1987;40(5):373–83.

    CAS  PubMed  Google Scholar 

  27. Kondo Y, Abe T, Kohshi K, Tokuda Y, Cook EF, Kukita I, et al. Revised trauma scoring system to predict in-hospital mortality in the mergency department: glasgow coma scale, age and systolic blood pressure score. Crit Care. 2011;15:191.

    Google Scholar 

  28. Baghi I, Shokrgozar L, Herfatkar MR, Nezhad Ehsan K, Mohtasham Amiri Z, et al. Mechanism of injury, glasgow coma scale, age, and systolic blood pressure: A new trauma scoring system to predict mortality in trauma patients. Trauma Mon. 2015;20:e24473.

    PubMed  PubMed Central  Google Scholar 

  29. Gennarelli T. The Abbreviated Injury Scale—1990 revision. Des Plaines: American Association for the Advancement of Automotive Medicine (AAAM); 1990.

    Google Scholar 

  30. Baker SP, O’Neill B, Haddon W Jr, Long WB, et al. The injury severity score: a method for describing patients with multiple injuries and evaluating emergency care. J Trauma. 1974;14:187–96.

    CAS  PubMed  Google Scholar 

  31. Lavoie A, Moore L, LeSage N, Liberman M, Sampalis JS, et al. The new injury severity score: a more accurate predictor of in-hospital mortality than the injury severity score. J Trauma. 2004;56:1312–20.

    PubMed  Google Scholar 

  32. Hagn S et al. Vergleich verschiedener Komorbiditäts-Scores in Routinedaten der stationären Versorgung. Medizinischen Fakultät der Ludwig-Maximilians-Universität zu München. Dissertation, 2014. https://edoc.ub.uni-muenchen.de/17118/1/Hagn_Stefan.pdf. Accessed 14 April 2019.

  33. OECD. Pensions at a Glance 2017: OECD and G20 Indicators, OECD Publishing, Paris. https://www.oecd-ilibrary.org/social-issues-migration-health/pensions-at-a-glance-2017_pension_glance-2017-en. Accessed 15 May 2019.

  34. WHO. World health statistics 2016: monitoring health for the SDGs, sustainable development goals.2017. https://www.who.int/gho/publications/world_health_statistics/2016/en/. Accessed 25 May 2019.

  35. Woodgate A et al. London Major Trauma System: Management of elderly major trauma patients - Second Edition. s.l. : NHS, 2018. https://www.c4ts.qmul.ac.uk/downloads/pan-london-major-trauma-system-elderly-trauma-guidancesecond-editiondecember-2018.pdf. Accessed 19 Jun 2019.

  36. Ouchi Y, Rakugi H, Arai H, Akishita M, Ito H, Toba K, Kai I, et al. Redefining the elderly as aged 75 years and older: Proposal from the Joint Committee of Japan Gerontological Society and the Japan Geriatrics Society. Geriatr Gerontol Int. 2017;17:1045–7.

    PubMed  Google Scholar 

  37. American College of Surgeons Committee on Trauma.Geriatric trauma. In: ATLS: student course manual. 8th Edition ACLS. Chicago: s.n., 2008; p. 247–57.

  38. Lefering R, Paffrath T, Bouamra O, Coats TJ, Woodford M, Jenks T, Wafaisade A, Nienaber U, Lecky F, et al. Epidemiology of in-hospital trauma deaths. Eur J Trauma Emerg Surg. 2012;38:3–9.

    CAS  PubMed  Google Scholar 

  39. Kuhne CA, Ruchholtz S, Kaiser GM, Nast-Kolb D, et al. Mortality in severely injured elderly trauma patients - when does age become a risk factor? World J Surgery. 2005;29:1476–82.

    Google Scholar 

  40. Jelodar S, Jafari P, Yadollahi M, Jahromi GS, Khalili H, Abbasi H, Bolandparvaz S, Paydar S, et al. Potential risk factors of death in multiple trauma patients. Emergency. 2017;2:170–3.

    Google Scholar 

  41. Campbell-Furtick MB, Moore BJ, Shafi S, et al. Post-trauma mortality increase at age 60: a cutoff for defining elderly? Am J Surg. 2016;212:781–5.

    PubMed  Google Scholar 

  42. Calland JF, Ingraham AM, Martin N, Marshall GT, Schulman CI, Stapelton T, Barraco RD et al. The Eastern Association for the Surgery of Trauma. Geriatric trauma (update). 2010. https://www.east.org/resources/teatment-guidelines/geriatric-trauma-(update) Accessed 28 Aug 2019.

  43. Beck B, Cameron P, Lowthian J, Fitzgerald M, Judson R, Gabbe BJ, et al. Major trauma in older persons. British J Surg. 2018;2:310–8.

    CAS  Google Scholar 

  44. Pape HC, Lefering R, Butcher N, Peitzman A, Leenen L, Marzi I, Lichte P, Josten C, Boullion B, Schmucker U, Stahel P, Giannoudis P, Balogh Z, et al. The definition of polytrauma revisited: an international consensus process and proposal of the new 'Berlin definition'. J Trauma Acute Care Surg. 2014;77:780–6.

    PubMed  Google Scholar 

  45. Schweizer Bevölkerungsdaten im Vergleich 1950–2017. Bundesamt für Statistik. 2018. https://www.bfs.admin.ch/bfs/de/home/statistiken/kataloge-datenbanken/tabellen.assetdetail.6046343.html Accessed 16 Dec 2018.

  46. Durchschnittliche Lebenserwartung Deutschland. Statistisches Bundesamt, Deutschland.2018. https://www.genesis.destatis.de/genesis/online/link/tabelleErgebnis/12613-0007. Accessed 12 Dec 2018.

  47. Williams TM, Sadjadi J, Harken AH, Victorino GP, et al. The necessity to assess anticoagulation status in elderly injured patients. J Trauma. 2008;65:772–6.

    PubMed  Google Scholar 

  48. Sammy I, Lecky F, Sutton A, Leaviss J, O’Cathain A, et al. Factors affecting mortality in older trauma patients - a systematic review and meta-analysis. Injury. 2016;47:1170–83.

    PubMed  Google Scholar 

  49. Schoeneberg C, Probst T, Schilling M, Wegner A, Hussmann B, Lendemans S, et al. Mortality in severely injured elderly patients: a retrospective analysis of a German level 1 trauma center (2002–2011). Scand J Trauma Resusc Emerg Med. 2014;22:45.

    PubMed  PubMed Central  Google Scholar 

  50. Franceschi C, Garagnani P, Morsiani C, Conte M, Santoro A, Grignolio A, Monti D, Capri M, Salvioli S, et al. The continuum of aging and age-related diseases: common mechanisms but different rates. Front Med. 2018;5:61.

    Google Scholar 

  51. Levine ME, Crimmins EM, et al. Is 60 the new 50? Examining changes in biological age over the past two decades. Demography. 2018;55:387–402.

    PubMed  Google Scholar 

  52. Shifflette VK, Lorenzo M, Mangram AJ, Truitt MS, Amos JD, Dunn EL, et al. Should age be a factor to change from a Level II to a Level I trauma activation? J Trauma. 2010;69:88–92.

    PubMed  Google Scholar 

  53. Demetriades D, Sava J, Alo K, Newton E, Velmahos GC, Murray JA, Belzberg H, Asensio JA, Berne TV, et al. Old age as a criterion for trauma team activation. J Trauma. 2001;51:754–7.

    CAS  PubMed  Google Scholar 

  54. Guidelines for field triage of injured patients: Recommendations of the National Expert Panel on Field Triage. Centers for Disease Control and Prevention. MMWR. 2011;2012(61):1–20.

    Google Scholar 

  55. Thompson HJ, McCormick WC, Kagan SH, et al. Traumatic brain injury in older adults: epidemiology, outcomes, and future implications. J Am Geriatr Soc. 2006;54:1590–5.

    PubMed  PubMed Central  Google Scholar 

  56. Labib N, Nouh T, Winocour S, Deckelbaum D, Banici L, Fata P, Razek T, Khwaja K, et al. Severly injured geriatric population: morbidity, mortality and risk factors. J Trauma. 2011;71(71):1908–14.

    PubMed  Google Scholar 

  57. Schoenborn CA, Heyman KM et al. Health characteristics of adults 55 years of age and over, United States, 2004–2007. 2008 https://stacks.cdc.gov/view/cdc/5335. Accessed 04 Sep 2019.

  58. Wihlke G, Strömmer L, Troëng T, Brattström O. Long-term follow-up of patients treated for traumatic injury regarding physical and psychological function and health-related quality of life. Eur J Trauma Emerg Surg. 2019. https://doi.org/10.1007/s00068-019-01170-w.

    Article  PubMed  Google Scholar 

  59. Gross T, Braken P, Amsler F. Trauma center need: the American College of Surgeons’ definition in contrast to Swiss highly specialized medicine regulations—a Swiss trauma center perspective. Eur J Trauma Emerg Surg. 2018. https://doi.org/10.1007/s00068-018-1027-3.

    Article  PubMed  Google Scholar 

  60. Gross T, Morell S, Amsler F. To what extent are main accident-insurer cases representative of all significantly injured? a swiss monocenter perspective. J Insur Med. 2019;48(1):65–78. https://doi.org/10.17849/insm-48-1-1-14.1.

    Article  PubMed  Google Scholar 

  61. Lee JS, Kim YH, Yun JS, Jung SE, Chae CS, Chung MJ. Characteristics of patients injured in road traffic accidents according to the new injury severity score. Ann Rehabil Med. 2016;40(2):288–93. https://doi.org/10.5535/arm.2016.40.2.288.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  62. Stevenson M, Segui-Gomez M, Lescohier I, Di Scala C, McDonald-Smith G. An overview of the injury severity score and the new injury severity score. Inj Prev. 2001;7(1):10–3. https://doi.org/10.1136/ip.7.1.10.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  63. Gross T, Morell S, Scholz SM, Amsler F. The capacity of baseline patient, injury, treatment and outcome data to predict reduced capacity to work and accident insurer costs – a Swiss prospective 4-year longitudinal trauma centre evaluation. Swiss Med Wkly. 2019;149:w20144.

    PubMed  Google Scholar 

Download references

Acknowlegements

The authors would like to thank all hospital collaborators, particularly Ms. F. Maeder and Ms. B. Wordel for the reliable management of data and Ms J. Buchanan for English language editing of the manuscript.

Funding

This study was funded by the Hospital (Kantonsspital Aarau AG).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Thomas Gross.

Ethics declarations

Conflict of interest

We have no conflict of interest to declare.

Ethical approval

All procedures performed in this study involving human participants were ininser accordance with the ethical standards of the institutional and/or national research committee. Furthermore, the 1964 Helsinki declaration and its later amendments and comparable ethical standards were obeyed. There were no animal studies performed by any of the authors.

Informed consent

Informed consent was obtained following the study protocol approved by the regional ethics committee.

Electronic supplementary material

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Fiumedinisi, F.A., Amsler, F. & Gross, T. Short-term outcome following significant trauma: increasing age per se has only a relatively low impact. Eur J Trauma Emerg Surg 47, 1979–1992 (2021). https://doi.org/10.1007/s00068-020-01357-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00068-020-01357-6

Keywords

Navigation