Zusammenfassung
In diesem Beitrag werden klinische Diagnostik, Differenzialdiagnostik, Laboruntersuchungen, multimodale Bildgebung sowie die medikamentöse Therapie der Vaskulitiden der kleinen, mittleren und großen Gefäße sowie granulomatöser und eosinophiler Erkrankungen in Anlehnung an die EULAR- und ACR-Empfehlungen beschrieben. Vaskulitiden sind ein Syndrom. Die einzelnen spezifischen Krankheitsbilder umfassen klinische Entitäten wie die Wegener-Granulomatose, die Polyangiitis, das Churg-Strauss-Syndrom, die Polyarteriitis (Panarteriitis) nodosa, die Kryglobulinämie und sonstige Vaskulitiden.
Abstract
In this article the diagnostics, differential diagnosis, laboratory findings, multimodal imaging and treatment of vasculitis of small, medium and large vessels as well as granulomatous and eosinophilic vascular diseases are described in the context of previous and current European League against Rheumatism (EULAR) and American College of Rheumatology (ACR) recommendations. Vasculitis is a syndrome which is part of various clinical disease entities, such as Wegener’s granulomatosis, polyangiitis, Churg-Strauss syndrome, polyarteritis nodosa, cryoglobulinemia and other forms of vasculitis.
Literatur
Hunder GG, Bloch DA, Michael BA et al (1990) The American College of Rheumatology 1990 criteria for the classification of giant cell arteritis. Arthritis Rheum 33:1122–1128
Jennette JC, Falk RJ, Andrassy K et al (1994) Nomenclature of systemic vasculitides. Proposal of an international consensus conference. Arthritis Rheum 37:187–192
Jennette JC, Falk RJ, Bacon PA et al (2013) 2012 revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides. Arthritis Rheum 65:1–11
Watts RA, Jolliffe VA, Carruthers DM et al (1996) Effect of classification on the incidence of polyarteritis nodosa and microscopic polyangiitis. Arthritis Rheum 39:1208–1212
Luqmani RA, Suppiah R, Grayson PC et al (2011) Nomenclature and classifification of vasculitis – update on the ACR/EULAR diagnosis and classification of vasculitis study (DCVAS). Clin Exp Immunol 164(Suppl 1):11–13
Watts RA, Suppish R, Merkel PA, Luqmani R (2011) Systemic vasculitis – is it time to reclassify? The way forward in approaching a diagnosis of vasculitis (Editorial). Rheumatology 50:643–645
Ozen S, Ruperto N, Dillon MJ et al (2005) EULAR/PReS endorsed consensus criteria for the classification of childhood vasculitides. Ann Rheum Dis 65:939–941
Yildiz C, Ozen S (2013) Childhood vasculitis. Acta Medica 2:16–22
Hernandez-Rodrıguez J, Molloy ES, Hoffman GS (2008) Single-organ vasculitis. Curr Opin Rheumatol 20(1):40–46
Classen M, Diehl V, Kochsiek K (2004) Innere Medizin, 5. Aufl. Urban & Fischer, München Jena
Numano F (2002) The story of Takayasu arteritis. Rheumatology 41(1):103–106
Horton BT, Magath TB, Brown GE (1932) An undescribed form of arteritis of the temporal vessels. Proc Mayo Clin 7:700–701
Ness T, Bley TA, Schmidt WA, Lamprecht P (2013) The diagnosis and treatment of giant cell arteritis. Dtsch Arztebl Int 110(21):376–386
Mukhtyar C, Guillevin L, Cid MC (2009) EULAR recommendations for the management of large vessel vasculitis. Ann Rheum Dis 68:318–323
Mazlumzadeh M, Hunder GG, Easley KA et al (2006) Treatment of giant cell arteritis using induction therapy with high-dose glucocorticoids: a double-blind, placebo-controlled, randomized prospective clinical trial. Arthritis Rheum 54:3310–3318
Lightfoot RW, Michel BA, Bloch DA et al (1990) The American College of Rheumatology 1990 criteria for the classification of polyarteritis nodosa. Arthritis Rheum 33:1088–1093
Mukhtyar C, Guillevin L, Cid MC et al (2009) EULAR recommendations for the management of primary small and medium vessel vasculitis. Ann Rheum Dis 68:310–317
Kussmaul A, Maier R (1866) Über eine bisher nicht beschriebene eigenthümliche Arterienerkrankung (Periarteriitis nodosa), die mit Morbus Brightii und rapid fortschreitender allgemeiner Muskellähmung einhergeht. Dtsch Arch Klin Med 1:484–515
Gross WL (ed) (1993) ANCA associated vasculitides, vol. 336. Plenum Press, New York London
Parrillo JE (1990) Heart disease and the eosinophil. N Engl J Med 323:1560–1561
Baandrup U (2012) Eosinophilic myocarditis. Herz 8:849–853
Ogbogu PU, Rosing DR, Horne MK (2007) Cardiovascular manifestations of hypereosinophilic syndromes. Immunol Allergy Clin North Am 27:457–475
Maisch B, Richter A, Koelsch S et al (2006) Management of patients with suspected (peri-) myocarditis and inflammatory dilated cardiomyopathy. Herz 31(9):881–890
Maisch B, Pankuweit S (2013) Standard and etiology-directed evidence-based therapies in myocarditis: state of the art and future perspectives. Heart Fail Rev 18(6):761–795
Maisch B, Ruppert V, Pankuweit S (2014) Management of fulminant myocarditis: a diagnosis in search of its etiology but with therapeutic options. Curr Heart Fail Rep 11(2):166–177
Maisch B, Seferovic PM, Ristic AD et al (2004) Guidelines on the diagnosis and management of pericardial diseases executive summary; The Task force on the diagnosis and management of pericardial diseases of the European Society of Cardiology. Eur Heart J 25(7):587–610
Maisch B, Ristic AD, Seferovic PM, Tsang TSM (2011) Interventional pericardiology. Springer, Berlin Heidelberg New York
Maisch B, Ristic AD, Pankuweit S (2002) Intrapericardial treatment of autoreactive pericardial effusion with triamcinolone; the way to avoid side effects of systemic corticosteroid therapy. Eur Heart J 23(19):1503–1508
Cogan DC (1945) Syndrome of nonsyphilitic interstitial keratitis and vestibuloauditory symptoms. Arch Ophthalmol 33:144–149
Lunardi C, Bason C, Leandri M et al (2002) Autoantibodies to inner ear and endothelial antigens in Cogan’s syndrome. Lancet 360(9337):915–921
Walter MA, Melzer RA, Schindler C et al (2005) The value of 18F-FDG PET in the diagnosis of large-vessel vasculitis and the assessment of activity and extent of disease. Eur J Nucl Med Mol Imaging 32:674–681
Balink H, Bruyn GA (2007) The role of PET/CT in Cogan’s syndrome. Clin Rheumatol 26:2177–2179
Maisch B, Ristic AD (2014) Diagnostik und Therapie der Perikarditis und des Perikardergusses. Herz 39:837–856
Dasgupta B, Cimmino MA, Maradit-Kremers H et al (2012) 2012 provisional classification criteria for polymyalgia rheumatica: a European League Against Rheumatism/American College of Rheumatology collaborative initiative. Ann Rheum Dis 71:484–492
Einhaltung ethischer Richtlinien
Interessenkonflikt. B. Maisch gibt an, dass kein Interessenkonflikt besteht.
Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Maisch, B. Vaskulitiden. Herz 40, 85–98 (2015). https://doi.org/10.1007/s00059-014-4200-4
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00059-014-4200-4
Schlüsselwörter
- Wegener-Granulomatose
- Polyangiitis
- Churg-Strauss-Syndrom
- Polyarteriitis (Panarteriitis) nodosa
- Kryglobulinämie