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Oculoauriculovertebral spectrum and maxillary sinus volumes

CT-based comparative evaluation

Okuloaurikulovertebrales Spektrum und Kieferhöhlenvolumina

Vergleichende CT-basierte Evaluation

  • Original Article
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Journal of Orofacial Orthopedics / Fortschritte der Kieferorthopädie Aims and scope Submit manuscript

Abstract

Objectives

To evaluate, by comparing maxillary sinus volumes, how asymmetries related to oculoauriculovertebral spectrum (OAVS) affect upper-jaw development.

Methods

From pre-existing multislice spiral computed tomography (MSCT) datasets, we selected 20 cases of 11 female and 9 male patients aged 6.1–24 years who were clinically and radiographically symmetrical (group 1) plus 20 cases of 8 female and 12 male patients aged 5.7–23.9 years who had OAVS (group 2). After three-dimensional reconstruction of the datasets, the volumes of the left and right maxillary sinuses were calculated and compared based on patient groups and based on the sides affected or unaffected by OAVS. To this end, the OAVS patients were subdivided into a group in whom both external acoustic pores were radiographically present (group 2a) and a group in whom the pore on the affected side was congenitally missing (group 2b).

Results

Intrarater reliability was very high (0.997). Significantly larger volumes of the maxillary sinuses, amounting to a mean of 13.4 ml, were observed in the control group than in the asymmetric OAVS groups where the volumes averaged 9.8 ml or 10.3 ml, respectively (p = 0.03). No statistically significant differences in sinus volumes were found between the two OAVS groups (p = 0.557) and between the sides affected or unaffected by the OAVS (p = 0.8311 in group 2a and 0.4961 in group 2b).

Conclusions

Overall, we found the volumes of both maxillary sinuses to be somewhat smaller in the asymmetric patients than in the symmetric control group. This might indicate that OAVS was associated with a mild generalized hypoplasia of the maxilla, but significantly different sinus volumes were not seen between the affected and unaffected sides.

Zusammenfassung

Zielsetzung

Das Ziel dieser Studie war die Untersuchung, inwieweit Asymmetrien des okuloaurikulovertebralen Spektrums (OAVS) die Entwicklung der Maxilla beeinflussen.

Methode

Aus vorhandenen MSCT(Mehrschicht-Spiral-Computertomographie)-Datensätzen wurden retrospektiv 20 Datensätze von Patienten mit OAVS (8 weiblich, 12 männlich, Altersbereich 5,7–23,9 Jahre) und 20 Datensätze von klinisch wie radiologisch symmetrischen Patienten (11 weiblich, 9 männlich, Altersbereich 6,1–24 Jahre) ausgewählt. Nach dreidimensionaler Rekonstruktion wurde das Volumen der beiden Sinus maxillares erfasst sowie patienten- und seitenspezifisch miteinander verglichen. Dabei wurde zwischen Patienten differenziert, bei denen beide Pori acustici externi angelegt waren (Gruppe 2a) und bei denen der Porus acusticus externus der betroffenen Seite nicht angelegt war (2b).

Ergebnisse

Die Intrauntersucherreliabilität war sehr hoch (0,997). Das Volumen der Kieferhöhlen war bei den Patienten der Kontrollgruppe mit 13,4 ml signifikant größer (p-Wert = 0,03) als bei den Patienten mit OAVS (Gruppe 2a: 9,8 ml; 2b: 10,3 ml). Die Unterschiede hinsichtlich der Volumina zwischen den beiden asymmetrischen Gruppen (p = 0,557) sowie zwischen betroffener und nichtbetroffener Seite stellten sich als nicht signifikant dar (2a p = 0,8311; 2b p = 0,4961).

Schlussfolgerung

Die Volumina der beiden Kieferhöhlen zeigten sich bei den untersuchten asymmetrischen Patienten – verglichen mit der symmetrischen Kontrollgruppe – insgesamt etwas kleiner, was auf eine dezente Unterentwicklung der Maxilla hindeuten kann. Zwischen der betroffenen und der nichtbetroffenen Seite gab es keine signifikanten Volumenunterschiede.

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Acknowledgements

This study was financially supported by the German Orthodontic Society (DGKFO).

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Authors and Affiliations

  1. Department of Orthodontics and Orofacial Orthopedics, Friedrich-Alexander University Erlangen-Nuernberg, Erlangen, Germany

    Elisabeth Hofmann, Andreas Detterbeck, Taras Chepura & Ursula Hirschfelder

  2. Department of Orthodontics, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, 93053, Regensburg, Germany

    Elisabeth Hofmann & Christian Kirschneck

  3. Department of Medical Biometry, Informatics and Epidemiology, Rheinische Friedrichs-Wilhelms University Bonn, Bonn, Germany

    Matthias Schmid

Authors
  1. Elisabeth Hofmann
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  2. Andreas Detterbeck
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  6. Ursula Hirschfelder
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Correspondence to Elisabeth Hofmann.

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Conflict of interest

E. Hofmann, A. Detterbeck, T. Chepura, C. Kirschneck, M. Schmid and U. Hirschfelder declare that they have no competing interests.

Ethical standards

This article does not contain any studies with human participants or animals performed by any of the authors. Consent was obtained from all patients identifiable from images or other information within the manuscript. In the case of underage patients, consent was obtained from a parent or legal guardian.

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Hofmann, E., Detterbeck, A., Chepura, T. et al. Oculoauriculovertebral spectrum and maxillary sinus volumes. J Orofac Orthop 79, 259–266 (2018). https://doi.org/10.1007/s00056-018-0141-5

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  • DOI: https://doi.org/10.1007/s00056-018-0141-5

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