Abstract
Sixteen novel thiadiazolium derivatives 6(a–h) and 12(a–h) were synthesized by conventional route starting from anthranilic acid using different acid chloride derivatives. The structure of all the newly synthesized compounds was established by IR, NMR, mass spectroscopy, and elemental analysis. The compounds were also screened for their antibacterial activity against some important bacterial species. Some of the compounds were found excellent active against these species.
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The authors express their sincere gratitude to Enzal Chemicals Ltd., Panoli and Chemcrux Enterprise Ltd., Ankleshwar for providing some important chemicals.
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Asundaria, S.T., Patel, N.S. & Patel, K.C. Synthesis, characterization, and antimicrobial studies of novel 1,3,4-thiadiazolium-5-thiolates. Med Chem Res 21, 1199–1206 (2012). https://doi.org/10.1007/s00044-011-9632-2
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DOI: https://doi.org/10.1007/s00044-011-9632-2