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Long-term results of laparoscopic adrenalectomy for primary aldosteronism

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Abstract

Background: The management of primary aldosteronism is currently achieved by both medical and surgical treatment. Laparoscopy has in recent years unquestionably become the gold standard in adrenal surgery for benign lesions. This study aims to evaluate our clinical results among patients who underwent laparoscopic adrenalectomy (LA) for primary aldosteronism. Methods: From January 1994 to January 2006, amid LA series, 59 primary aldosteronism patients were treated in our institution. Patients were 33 males and 26 females with mean age 49.3 yr (19–78). The mean body mass index was 25.9 kg/m2 (20.5–33.3). The mean size of lesion was 2.9 cm (1–5.5). Clinical symptoms were as follows: hypertension and symptomatic/asymptomatic hypokalemia (54), hypokalemia (5). Results: Thirty-five left and 24 right LA were performed. On the left side, 22 procedures were carried out by anterior approach, 9 by anterior sub-mesocolic route, and 4 by means of flank approach. All right procedures were completed by the anterior supine approach. The mean operative time was 103.5 min for left and 92.8 min for right adrenalectomy. There was one major complication, a colonic post-operative fistula, regarding a left adrenalectomy case. The mean post-operative hospital stay was 3 days (1–9). The cure rate of hypertension and hypokalemia was similar to the current literature results. Conclusions: LA is a safe and effective option in the treatment of primary aldosteronism. Appropriate selection of patients, larger adrenal masses and duration of symptoms are determining factors in the success rate of hypertension management.

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Authors and Affiliations

  1. General Surgery and Surgery Methodology Clinic, Polytechnic University of Marche, Hospitals of Ancona, Ancona

    R. Campagnacci MD, F. Crosta, A. De Sanctis, M. Baldarelli, M. Coletta & M. Guerrieri

  2. Endocrinology Clinic, Polytechnic University of Marche, Hospitals of Ancona, Ancona

    G. Giacchetti

  3. “Paride Stefanini” Surgery Department, II Surgery Clinic, “Sapienza” University, Rome, Italy

    A. M. Paganini

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  1. R. Campagnacci MD
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  2. F. Crosta
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  3. A. De Sanctis
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  4. M. Baldarelli
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  5. G. Giacchetti
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Correspondence to R. Campagnacci MD.

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Campagnacci, R., Crosta, F., De Sanctis, A. et al. Long-term results of laparoscopic adrenalectomy for primary aldosteronism. J Endocrinol Invest 32, 57–62 (2009). https://doi.org/10.1007/BF03345680

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