Abstract
Background and aims: Electrocardiographic (ECG) abnormalities are often found in older patients but relatively few epidemiological studies have been performed. This study describes: a) cross-sectional differences in ECG abnormalities among three 70-year-old cohorts born over a period of 30 years; b) longitudinal changes in ECG abnormalities from the age of 70 to 85; and c) the relationship between ECG abnormalities at age 70 and subsequent 10- and 15-year mortality in men and women. Methods: Trends in the prevalence of ECG abnormalities were investigated among 2100 70-year olds (994 men, 1106 women) from three cohorts born in 1901/02 (I), 1911/12 (III) and 1930 (VI). Longitudinal changes and mortality risks were investigated among 973 70-year olds (449 men and 524 women) from cohort I, which was followed from 1971 until 2001. Results: In both sexes, the prevalence of ECG abnormalites was significantly lower in the later-born cohorts. From age 70 to 85, there was an increase in both men and women of large or intermediate Q-waves, left axis deviation, negative T-waves (0-5 mm), complete right bundle branch block (RBBB), and atrial fibrillation or flutter. Compared with those with no ECG abnormalities, the mortality risk was higher among individuals with large and intermediate Q-waves and negative T-waves (>-1 mm) in both sexes, and STJ depression >-0.5 mm and complete LBBB together with complete RBBB and intraventricular block; QRS>-0.12 sec in men only. Conclusions: ECG abnormalities are frequent in the elderly, they increase with age, and are associated with increased mortality.
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References
Fye BW. A history of the origin, evolution, and impact of electrocardiography. Am J Cardiol 1994; 73: 937–49.
Furberg CD, Manolio TA, Psaty BM, et al. Major electrocardiographic abnormalities in persons aged 65 years and older (The Cardiovascular Health Study). Am J Cardiol 1992; 65: 1329–35.
Kennedy RD, Caird FI. The application of the Minnesota Code to population studies of the electrocardiogram in the elderly. Gerontol Clin 1972; 14: 5–16.
Tervahauta M., Perkkanen J., Punsar S., Nissinen A. Resting electrocardiographic abnormalities as predictors of coronary events and total mortality among elderly men. Am J Med 1996; 100: 641–5.
Rao X, Wu X, Folsom AR, Liu X, et al. Comparison of electrocardiographic findings between Northern and Southern Chinese population samples. Int J Epidemiol 2000; 29: 77–84.
Strogatz DS, Tyroler HA, Watkins LO, Hames CG. Electro graphic abnormalities and mortality among middle-aged black men and white men of Evans County, Georgia. J Chron Dis 1987; 40: 149–55.
Crow RS, Prineas RJ, Hannan PJ, Grandits G, Blackburn H. Prognostic associations of Minnesota Code serial electrocardiographic change classification with coronary heart disease mortality in the multiple risk factor intervention trial. Am J Cardiol 1997; 80: 138–44.
Bachman S, Sparrow D, Smith LK. Effect of aging on the electrocardiogram. Am J Cardiol 1981; 48: 513–6.
Casiglia E, Spolaore P, Ginocchio G, et al. Mortality in relation to Minnesota code items in elderly subjects. Sex-related differences in a cardiovascular study in the elderly. Jpn Heart J 1993; 34: 567–77.
Hedenrud B, Landahl S, Mellström D, et al. Electrocardiogram at age 70 and 75. A longitudinal study. I. General presentation of findings. J Clin Exp Gerontol 1980; 4: 231–3.
Ahto M, Isoaho R, Puolijoki H, et al. Prevalence of coronary heart disease, associated manifestations and electrographic findings in elderly Finns. Age Ageing 1998; 27: 729–37.
Blackburn H, Keys A, Simonsson E, et al. The electrocardiogram in population studies. A classification system. Circulation 1960; 21: 1160–75.
Prineas RJ, Crow RS, Blackburn H. The Minnesota Code manual of electrocardiographic findings: standards and procedures for measurement and classification. In Wright J, Ed. Boston: Little-john M, 1982.
Rinder L, Roupe S, Steen B, Svanborg A. Seventy-year-old people in Gothenburg. A population study in an industrialized Swedish city. I. General presentation of the study. Acta Med Scand 1975; 198: 397–407.
Steen B. The elderly yesterday, today and tomorrow: Aspects on cohort differences from the gerontological and geriatric population studies in Göteborg, Sweden (H70). Arch Gerontol Geriatr 2002; Suppl.8: 359–70.
Eriksson BG, Mellström D, Svanborg A. A medical-social intervention in a 70-year-old Swedish population. A general presentation of methodological experience. Compr Gerontol 1987; 1: 49–56.
Rose GA, Blackburn H. Cardiovascular survey methods. Monogr Ser WHO 1968; 56: 1–188.
Menotti A, Mulder I, Kromhout D, et al. The association of silent electrographic findings with coronary deaths among elderly men in three European countries. The Fine study. Acta Cardiol 2001; 56: 27–36.
Crow RS, Prineas RJ, Jacobs DR, Blackburn H. A new epidemiological classification system for interim myocardial infarction from serial electrocardiographic changes. Am J Cardiol 1989; 64: 454–6.
Steen G, Berg S, Steen B. Cognitive function in 70-year-old men and women. A 16-year cohort difference population study. Aging Exp Clin Res 1998; 10: 120–6.
Rothenberg E, Bosaeus I, Steen B. Food habits and nutrient intake in three 70-year-old free living populations in Gothenburg. Scand J Nutr/ Näringsforskning 1996; 312: 1459–62.
Oopik AJ, Dorogy M, Devereux RB, et al. Major electrographic abnormalities among American Indians aged 45 to 74 years (The Strong Heart Study). Am J Cardiol 1996; 78: 1400–5.
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Molander, U., Kumar Dey, D., Sundh, V. et al. ECG abnormalities in the elderly: Prevalence, time and generation trends and association with mortality. Aging Clin Exp Res 15, 488–493 (2003). https://doi.org/10.1007/BF03327371
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DOI: https://doi.org/10.1007/BF03327371