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The selection of double heterozygotes

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Summary

Selection in favour of double heterozygotes leads to different types of equilibrium according to the linkage between the loci concerned. For slight selection or loose linkage coupling and repulsion should be equally frequent. When the selection or the linkage becomes sufficiently intense there is an equilibrium when almost all or almost none of the double heterozygotes are in coupling.

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Reference

  • Haldane, J. B. S. (1924). A mathematical theory of natural and artificial selection, Part I.Trans Camb. Phil. Soc.,23, 19–41.

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Haldane, J.B.S. The selection of double heterozygotes. J Genet 58, 125–128 (1962). https://doi.org/10.1007/BF02986124

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  • DOI: https://doi.org/10.1007/BF02986124

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