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Expression of human immunodeficiency virus-1 in human colonic cells

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References

  1. Rodgers VD, Kagnoff MF: Acquired immunodeficiency syndrome and disease of the gastrointestinal tract. Immunol Allergy Clin North Am 1988;8: 451–467.

    Google Scholar 

  2. Maddon PJ, Dalgleish AG, McDougal JS, Clapham PR, Weiss RA, Axel R: The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain. Cell 1986;47:333–348.

    Article  PubMed  CAS  Google Scholar 

  3. Clapham PR, Weber JN, Whitby D, McIntosh K, Dalgleish AG, Maddon PJ, Deen KC, Sweet RW, Weiss RA: Soluble CD4 blocks the infectivity of diverse strains of HIV and SIV for T cells and monocytes but not for brain and muscle cells. Nature 1989;337:368–370.

    Article  PubMed  CAS  Google Scholar 

  4. Harouse JM, Kunsch C, Hartle HT, Laughlin MA, Hoxie JA, Wigdahl B, Gonzalez-Scarano F: CD4-independent infection of human neural cells by human immunodeficiency virus type 1. J Virol 1989;63:2527–2533.

    PubMed  CAS  Google Scholar 

  5. Tateno M, Gonzalez-Scarano F, Levy JA: Human immunodeficiency virus can infect CD4-negative human fibroblastoid cells. Proc Natl Acad Sci USA 1989;86:4287–4290.

    Article  PubMed  CAS  Google Scholar 

  6. Nelson JA, Wiley CA, Reynolds-Kohler C, Reese CE, Margaretten W, Levy JA: Human immunodeficiency virus detected in bowel epithelium from patients with gastrointestinal symptoms. Lancet 1988;i:259–262.

    Article  Google Scholar 

  7. Levy JA, Margaretten W, Nelson J: Detection of HIV in enterochromaffin cells in the rectal mucosa of an AIDS patient. Am J Gastroenterol 1989;84:787–789.

    PubMed  CAS  Google Scholar 

  8. Fox CH, Kotler D, Tierney A, Wilson CS, Fauci AS: Detection of HIV-1 RNA in the lamina propria of patients with AIDS and gastrointestinal disease. J Infect Dis 1989;159:467–471.

    PubMed  CAS  Google Scholar 

  9. Adachi A, Koenig S, Gendelman HE, Daugherty D, Gattoni-Celli S, Fauci AS, Martin MA: Productive, persistent infection of human colorectal cell lines with human immunodeficiency virus. J Virol 1986;61:209–213.

    Google Scholar 

  10. Chen C, Okayama H: High-efficiency transformation of mammalian cells by plasmid DNA. Mol Cell Biol 1987;7:2745–2752.

    PubMed  CAS  Google Scholar 

  11. Peterlin BM, Luciw PA, Barr PJ, Walker MD: Elevated levels of mRNA can account for the transactivation of human immunodeficiency virus. Proc Natl Acad Sci USA 1986;83:9734–9738.

    Article  PubMed  CAS  Google Scholar 

  12. Heisig V, Benter T, Josephs S, Sadale MR, Okamoto T, Gallo RC: Intoraction of viral and cellular factors with the HTLV-III LTR with target sequences in vitro: Neth R, Gallo RC, Greaves MF, Kabisch HM (eds): Berlin, Springer, 1987, pp 423–429.

    Google Scholar 

  13. Nabel G, Baltimore D: An inducible transcription factor activates expression of human immunodeficiency virus in T cells. Nature 1987;326:711–713.

    Article  PubMed  CAS  Google Scholar 

  14. Gorman CM, Moffat LF, Howard BH: Recombinant genomes which express chloramphenicol acetyl transferase in mammalian cells. Mol Cell Biol 1982;2:1044–1051.

    PubMed  CAS  Google Scholar 

  15. Vongkovit P, Dinh S, Kachintorn U, Beuerlein G, Dharmsathaphorn K: Dual effects on diacylglycerol and phorbol ester on Cl negative secretion in T84 cells. Gastroenterology 1989;96:A532.

    Google Scholar 

  16. Lenardo MJ, Baltimore D: NEκB: A pleiotropic mediator of inducible and tissue-specific gene control. Cell 1989;58:227–229.

    Article  PubMed  CAS  Google Scholar 

  17. Omary MB, Brenner DA, de Grandpre LY, Roebuck KA, Richman DD, Kagnoff MF: HIV-1 infection and expression in human colonic cells: infection and expression in CD4+ and CD4 cell lines. AIDS 1991;5:275–281.

    Article  PubMed  CAS  Google Scholar 

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This work was supported by a National Institutes of Health Grant DK40582.

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Kagnoff, M.F., Omary, M.B., de Grandpre, L.Y. et al. Expression of human immunodeficiency virus-1 in human colonic cells. Immunol Res 10, 452–455 (1991). https://doi.org/10.1007/BF02919741

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